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This handbook provides practical clinical guidance on effectively selecting, prescribing and monitoring antiepileptic drugs. It also discusses the advantages and disadvantages of various drug therapies.

Anticonvulsants --- Epilepsy --- Brain --- Developmental disabilities --- Convulsions --- Spasms --- Anti-epileptic drugs --- Anticonvulsant drugs --- Antiepileptic agents --- Antiepileptics --- Central nervous system depressants --- Muscle relaxants --- Chemotherapy --- Diseases --- therapeutic use --- drug therapy --- Anticonvulsants - therapeutic use - handbooks --- Epilepsy - drug therapy - handbooks

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

sudden death --- blood pressure --- apnea --- sleep --- ketogenic diet --- epilepsy --- seizures --- mortality

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Fifty million people worldwide have epilepsy and yet up to 35% of patients experience seizures that are resistant to anti-epileptic drugs. Patients with medication-resistant epilepsy have increased risks of premature death, psychosocial dysfunction and a reduced quality of life. This key resource delivers guidance for all clinicians involved in caring for patients with medication-resistant epilepsy in order to reduce these risks. Covering the epidemiology, biology, causes and potential treatments for medication-resistant epilepsy, this definitive and focused text reviews the clinical care needs of patients. Guidance is practical and includes treatment for specialized groups including pediatric patients and those with psychiatric comorbidities. Several promising non-pharmacologic interventions available for patients, such as surgery, neuromodulation diet therapy and botanical treatment are explored in detail. Leading international figures from a range of disciplines bring their expertise together holistically in this essential manual.

Epilepsy.