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This book addresses the design of emerging conceptual tools, technologies and systems including novel synthetic parts, devices, circuits, oscillators, biological gates, and small regulatory RNAs (riboregulators and riboswitches), which serve as versatile control elements for regulating gene expression. Synthetic biology, a rapidly growing field that involves the application of engineering principles in biology, is now being used to develop novel systems for a wide range of applications including diagnostics, cell reprogramming, therapeutics, enzymes, vaccines, biomaterials, biofuels, fine chemicals and many more. The book subsequently summarizes recent developments in technologies for assembling synthetic genomes, minimal genomes, synthetic biology toolboxes, CRISPR-Cas systems, cell-free protein synthesis systems and microfluidics. Accordingly, it offers a valuable resource not only for beginners in synthetic biology, but also for researchers, students, scientists, clinicians, stakeholders and policymakers interested in the potential held by synthetic biology.
Systems biology. --- Genetic engineering. --- Gene expression. --- Medical genetics. --- Electronic circuits. --- Systems Biology. --- Genetic Engineering. --- Gene Expression. --- Gene Function. --- Circuits and Systems. --- Electron-tube circuits --- Electric circuits --- Electron tubes --- Electronics --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Genes --- Genetic regulation --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic recombination --- Biotechnology --- Transgenic organisms --- Computational biology --- Bioinformatics --- Biological systems --- Molecular biology --- Genetic aspects --- Expression --- Synthetic biology. --- Biology --- Engineering --- Bioengineering --- Bioenginyeria --- Expressió gènica --- Enginyeria biomèdica --- Enginyeria clínica --- Enginyeria mèdica --- Biofísica --- Enginyeria --- Medicina --- Electrònica mèdica --- Enginyeria de teixits --- Materials biomèdics --- Aparells i instruments mèdics --- Expressió dels gens --- Expressió genètica --- Expressivitat genètica --- Expressivitat gènica --- Ressenya genètica --- Regulació genètica --- Vectors genètics --- Enginyeria biològica --- Biologia --- Biònica --- Biotelemetria --- Enginyeria agronòmica --- Guerra biològica
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"Offers basic understanding and a clear picture of various microbial cell factories. Explains state-of-the-art tools and technologies including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer aided design, OMICS tools and many. Harnesses the potential of engineered microbial cell factories for the production of a wide range of biomolecules for industrial, therapeutic, pharmaceuticals, nutraceutical, and biotechnological applications. Highlights the advances, challenges, future opportunities in designing microbial cell factories"--
Microbial biotechnology. --- Biomolecules. --- Biological molecules --- Molecules --- Molecular biology --- Microorganisms --- Biotechnology --- Industrial microbiology --- Biotechnological microorganisms
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New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more.
Synthetic biology. --- Biology --- Engineering --- Bioengineering --- Biotechnology --- Synthetic Biology
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This book addresses the design of emerging conceptual tools, technologies and systems including novel synthetic parts, devices, circuits, oscillators, biological gates, and small regulatory RNAs (riboregulators and riboswitches), which serve as versatile control elements for regulating gene expression. Synthetic biology, a rapidly growing field that involves the application of engineering principles in biology, is now being used to develop novel systems for a wide range of applications including diagnostics, cell reprogramming, therapeutics, enzymes, vaccines, biomaterials, biofuels, fine chemicals and many more. The book subsequently summarizes recent developments in technologies for assembling synthetic genomes, minimal genomes, synthetic biology toolboxes, CRISPR-Cas systems, cell-free protein synthesis systems and microfluidics. Accordingly, it offers a valuable resource not only for beginners in synthetic biology, but also for researchers, students, scientists, clinicians, stakeholders and policymakers interested in the potential held by synthetic biology.
Genetics --- Molecular biology --- Biology --- Human genetics --- Electrical engineering --- Biotechnology --- medische genetica --- biologie --- genetische manipulatie --- elektrische circuits --- genexpressie
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This book provides a comprehensive overview of genomics and its diverse applications. Chapters cover genomics data generation methods, computational tools, gene annotation, transcriptomics, DNA barcoding, next-generation sequencing, functional genomics, metagenomics, synthetic genomics, microarray analysis, nutrigenomics, genome editing, and more. This book offers a valuable source of information for not only beginners in genomics, but also for students, researchers, scientists, clinicians, practitioners, policymakers, and stakeholders who are interested in harnessing the potential of genomics in many areas.
Genetics. --- Genomics. --- Genetic transcription. --- Pharmacovigilance. --- Synthetic Biology. --- Biology --- Genetics and Genomics. --- Gene Transcription. --- Drug Safety and Pharmacovigilance. --- Biological Techniques. --- Technique.
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Biological techniques --- Genetics --- Pharmacology. Therapy --- Biotechnology --- biologische technieken --- genetica --- biotechnologie --- drugbeleid
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Bioinformatics. --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Data processing --- Bioinformàtica
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This book presents the latest developments in bioinformatics, highlighting the importance of bioinformatics in genomics, transcriptomics, metabolism and cheminformatics analysis, as well as in drug discovery and development. It covers tools, data mining and analysis, protein analysis, computational vaccine, and drug design. Covering cheminformatics, computational evolutionary biology and the role of next-generation sequencing and neural network analysis, it also discusses the use of bioinformatics tools in the development of precision medicine. This book offers a valuable source of information for not only beginners in bioinformatics, but also for students, researchers, scientists, clinicians, practitioners, policymakers, and stakeholders who are interested in harnessing the potential of bioinformatics in many areas. .
Qualitative chemical analysis --- Quantitative chemical analysis --- Chemistry --- Biomathematics. Biometry. Biostatistics --- Artificial intelligence. Robotics. Simulation. Graphics --- analytische chemie --- bio-informatica --- KI (kunstmatige intelligentie) --- proteïnen --- AI (artificiële intelligentie)
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The second edition of Advances in Bioinformatics presents the latest developments in bioinformatics in gene discovery, genome analysis, genomics, transcriptomics, proteomics, metabolomics, metabolic flux analysis, drug discovery, and drug repurposing. It includes advancements in the applications of bioinformatics in the analysis of non-coding RNA, next-generation sequencing, gene synthesis, genome-scale modeling, high throughput drug screening, precision medicine, automation, artificial intelligence, and machine learning. Additionally, the book highlights some of the areas in which bioinformatics resources and methods are being developed to support the drug discovery pipeline. The chapter also discusses the role of bioinformatics in modeling and simulations of molecular biology systems in pathways identification and design. It is a valuable source of information for beginners in bioinformatics and students, researchers, scientists, clinicians, practitioners, policymakers, and stakeholders who are interested in harnessing the potential of bioinformatics in biomedical and allied sciences.
Bioinformatics. --- Proteins. --- Genomics. --- Chemoinformatics. --- Artificial intelligence. --- Cheminformatics. --- Artificial Intelligence.
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This book introduces the rapidly evolving field of multi-omics in understanding the human microbiome. The book focuses on the technology used to generate multi-omics data, including advances in next-generation sequencing and other high-throughput methods. It also covers the application of artificial intelligence and machine learning algorithms to the analysis of multi-omics data, providing readers with an overview of the powerful computational tools that are driving innovation in this field. The chapter also explores the various bioinformatics databases and tools available for the analysis of multi-omics data. The book also delves into the application of multi-omics technology to the study of microbial diversity, including metagenomics, metatranscriptomics, and metaproteomics. The book also explores the use of these techniques to identify and characterize microbial communities in different environments, from the gut and oral microbiome to the skin microbiome and beyond. Towards the end, it focuses on the use of multi-omics in the study of microbial consortia, including mycology and the viral microbiome. The book also explores the potential of multi-omics to identify genes of biotechnological importance, providing readers with an understanding of the role that this technology could play in advancing biotech research. Finally, the book concludes with a discussion of the clinical applications of multi-omics technology, including its potential to identify disease biomarkers and develop personalized medicine approaches. Overall, this book provides readers with a comprehensive overview of this exciting field, highlighting the potential for multi-omics to transform our understanding of the microbial world.
Microbiology. --- Medical microbiology. --- Bioinformatics. --- Medical Microbiology. --- Human body
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