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This book provides a comprehensive survey of the pharmacokinetic models used for the quantitative interpretation of contrast-enhanced imaging. It discusses all the available imaging technologies and the problems related to the calibration of the imaging system and accuracy of the estimated physiological parameters. Enhancing imaging modalities using contrast agents has opened up new opportunities for going beyond morphological information and enabling minimally invasive assessment of tissue and organ functionality down to the molecular level. In combination with mathematical modeling of the contrast agent kinetics, contrast- enhanced imaging has the potential to provide clinically valuable additional information by estimating quantitative physiological parameters. The book presents the broad spectrum of diagnostic possibilities provided by quantitative contrast-enhanced imaging, with a particular focus on cardiology and oncology, as well as novel developments in the area of quantitative molecular imaging along with their potential clinical applications. Given the variety of available techniques, the choice of the appropriate imaging modality and the most suitable pharmacokinetic model is often challenging. As such, the book provides a valuable technical guide for researchers, clinical scientists, and experts in the field who wish to better understand and properly apply tracer-kinetic modeling for quantitative contrast-enhanced imaging.
Contrast-enhanced magnetic resonance imaging. --- Contrast media (Diagnostic imaging) --- Contrast agents (Diagnostic imaging) --- Contrast media --- Diagnostic imaging --- Contrast-enhanced MRI --- Magnetic resonance imaging --- Equipment and supplies --- Radiology, Medical. --- Oncology. --- Imaging / Radiology. --- Signal, Image and Speech Processing. --- Cancer Research. --- Biological and Medical Physics, Biophysics. --- Tumors --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Radiology. --- Signal processing. --- Image processing. --- Speech processing systems. --- Cancer research. --- Biophysics. --- Biological physics. --- Biological physics --- Biology --- Medical sciences --- Physics --- Cancer research --- Computational linguistics --- Electronic systems --- Information theory --- Modulation theory --- Oral communication --- Speech --- Telecommunication --- Singing voice synthesizers --- Pictorial data processing --- Picture processing --- Processing, Image --- Imaging systems --- Optical data processing --- Processing, Signal --- Information measurement --- Signal theory (Telecommunication) --- Radiological physics --- Radiation
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This book provides a comprehensive survey of the pharmacokinetic models used for the quantitative interpretation of contrast-enhanced imaging. It discusses all the available imaging technologies and the problems related to the calibration of the imaging system and accuracy of the estimated physiological parameters. Enhancing imaging modalities using contrast agents has opened up new opportunities for going beyond morphological information and enabling minimally invasive assessment of tissue and organ functionality down to the molecular level. In combination with mathematical modeling of the contrast agent kinetics, contrast- enhanced imaging has the potential to provide clinically valuable additional information by estimating quantitative physiological parameters. The book presents the broad spectrum of diagnostic possibilities provided by quantitative contrast-enhanced imaging, with a particular focus on cardiology and oncology, as well as novel developments in the area of quantitative molecular imaging along with their potential clinical applications. Given the variety of available techniques, the choice of the appropriate imaging modality and the most suitable pharmacokinetic model is often challenging. As such, the book provides a valuable technical guide for researchers, clinical scientists, and experts in the field who wish to better understand and properly apply tracer-kinetic modeling for quantitative contrast-enhanced imaging.
General biophysics --- Oncology. Neoplasms --- Physical methods for diagnosis --- Computer. Automation --- beeldverwerking --- biofysica --- spraaktechnologie --- pneumologie --- oncologie --- radiologie --- medische beeldvorming --- moleculaire biologie --- signaalverwerking
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