Narrow your search

Library

AP (2)

EhB (2)

KDG (2)

KU Leuven (2)

LUCA School of Arts (2)

Odisee (2)

Thomas More Kempen (2)

Thomas More Mechelen (2)

UCLL (2)

ULB (2)

More...

Resource type

book (4)

digital (2)


Language

English (6)


Year
From To Submit

2007 (3)

2006 (3)

Listing 1 - 6 of 6
Sort by

Digital
35th Hemophilia Symposium : Hamburg 2004
Authors: ---
ISBN: 9783540285465 Year: 2006 Publisher: Berlin, Heidelberg Springer Verlag Berlin Heidelberg

Loading...
Export citation

Choose an application

Bookmark

Abstract


Digital
36th Hemophilia Symposium Hamburg 2005
Authors: ---
ISBN: 9783540367154 Year: 2007 Publisher: Berlin, Heidelberg Springer Verlag Berlin Heidelberg

Loading...
Export citation

Choose an application

Bookmark

Abstract

35th Hemophilia Symposium Hamburg 2004 : Epidemiology;Risk of Infections and Inhibitors in Hemophilia; Chronic lic Synovitis and Long-term Results of Orthopedic Treatment;Laboratory Diagnostics:Coagulation Factors; Inhibitors, Monitoring;Pediatric Hemostaseology;Free Lectures
Authors: --- ---
ISBN: 1280610484 9786610610488 3540285466 3540285431 Year: 2006 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

Loading...
Export citation

Choose an application

Bookmark

Abstract

Motion analysis as introduced 2 years ago on a national basis effectively identifies individual functional disorders and provides a means for describing them on the basis of a score. Individual therapy planning is possible. More treatment tends to produce better function scores and thus helps to lower the strain on the joint. Further study is required in order to determine whether this reduces the incidence of bleeding. Knee function is age-dependent. Height, weight and sporting activity seem to be influencing factors.Demeanor,pain,fatigue and parental motivation do not seem to have an impact. The roll-and-glide pattern is not age-dependent and probably shows functional abnormalities of the knee.Functional benchmarking of the sites is possible but d- ficult because each site selects the children differently.Age differences also render an overall assessment difficult. Some sites performed negative screening so as to only test children with more severe problems,while other sites performed no such selection.In other sites,the only children to show up for motion analysis were those with well informed parents and who are always involved in all the other activities on offer too.

36th Hemophilia Symposium Hamburg 2005 : Epidemiology; Hemophilia Therapy - Management of Bleedings and Inhibitors; Orthopedic Treatment in Hemophiliacs; Hemostaseologic Diagnosis; Pediatric Hemostaseology; Free Lectures
Authors: --- ---
ISBN: 1280803800 9786610803804 3540367152 3540367144 Year: 2007 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

Loading...
Export citation

Choose an application

Bookmark

Abstract

This book contains the contribution to the 36th Hemophilia Symposium, Hamburg 2005. The main topics are epidemiolgy, hemophilia therapy, orthopedic treatment in hemophiliacs, hemostaseologic diagnosis and pediatric hemostaseology. The volume is rounded off by numerous free papers and posters on hemophilia, inhibitors in hemophilia and diagnostics.


Book
35th Hemophilia Symposium : Hamburg 2004
Authors: --- ---
ISBN: 9783540285465 Year: 2006 Publisher: Berlin Heidelberg Springer Berlin Heidelberg

Loading...
Export citation

Choose an application

Bookmark

Abstract

Motion analysis as introduced 2 years ago on a national basis effectively identifies individual functional disorders and provides a means for describing them on the basis of a score. Individual therapy planning is possible. More treatment tends to produce better function scores and thus helps to lower the strain on the joint. Further study is required in order to determine whether this reduces the incidence of bleeding. Knee function is age-dependent. Height, weight and sporting activity seem to be influencing factors.Demeanor,pain,fatigue and parental motivation do not seem to have an impact. The roll-and-glide pattern is not age-dependent and probably shows functional abnormalities of the knee.Functional benchmarking of the sites is possible but d- ficult because each site selects the children differently.Age differences also render an overall assessment difficult. Some sites performed negative screening so as to only test children with more severe problems,while other sites performed no such selection.In other sites,the only children to show up for motion analysis were those with well informed parents and who are always involved in all the other activities on offer too.


Book
36th Hemophilia Symposium Hamburg 2005
Authors: --- ---
ISBN: 9783540367154 Year: 2007 Publisher: Berlin Heidelberg Springer Berlin Heidelberg

Loading...
Export citation

Choose an application

Bookmark

Abstract

About 31% of the patients with a factor VIII replacement therapy develop a factor VIII inhibitor.From these are 23% low-responder (< 5BE) and 77% high-responder (> 5BE) [8].In the case of severe hemophilia B,about 10.5% of the patients develop inhibitory antibodies [9]. Anti-factor VIII-antibodies are also seen in 15-78% healthy people without hemophilia [7, 17, 19]. Lacroix-Desmazes et al. [10, 11] showed anti-idiotypic antibodies neutralizing the inhibitory activity of the an- factor VIII antibodies in healthy people. Well-known predisposing factors for inhibitor formation are genetic features of factor VIII,which include large deletions,nonsense mutations or intrachromosomal recombinations [5, 23].Also, ethnic groups other than Caucasians (e.g.Africans) have a higher risk of developing inhibitors.Other risk factors are presumably de- ved from the immune system. For instance, a reduction of the inhibitor was seen with lower CD4+ T helper cell counts in HIV positive hemophilic patients [3,4].The development of inhibitors is very likely to be a Th-2 mediated event where cyto- nes and their receptors,T-cell receptors and the Major Histocompatibility Complex may also play an important role. Theoretical Background The substituted factor is an unknown protein for patients with a severe he- philia. Fig. 1. The normal immunoresponse (according to BAENKLER [2]) Abbreviations: TCR - T cell-receptor; APC - antigen presenting cell 36 I.Wieland et al.

Listing 1 - 6 of 6
Sort by