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Book
Tumor Deposits : Mechanism, Morphology and Prognostic Implications
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ISBN: 3319685821 3319685813 Year: 2018 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Abstract

This book presents the morphology, possible mechanisms of formation, and clinical relevance of tumor deposits (TDs) in different organs and parts of the body. It also describes the diagnostic features that are currently available for TDs and discusses the prognostic impact of TDs. The poor prognostic and predictive values of TDs were found to be as strong as distant metastasis in different series.  TDs, best characterized by colorectal cancer, are irregular discrete tumor masses that are discontinuous from the leading edge of the tumor. However, even in colorectal cancers, the place of TDs in tumor staging (tumor, lymph node and distant metastasis categories) remains controversial. This book presents the possible mechanisms of TD formation, including neurotrophic and angiotrophic extravascular migratory metastasis, in comparison with the well-known mechanisms of metastasis. It also shows that TDs were identified in esophageal, gastric, salivary gland, head and neck, and breast carcinomas. The possible mechanisms leading to the frequent association of TDs and peritoneal carcinomatosis are discussed.  This is a valuable resource for pathologists, oncologists, and surgeons who are looking for detailed information on the latest scientific insights into the pathology and prognostic implications of TDs.


Digital
Tumor Deposits : Mechanism, Morphology and Prognostic Implications
Author:
ISBN: 9783319685823 Year: 2018 Publisher: Cham Springer International Publishing

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Abstract

This book presents the morphology, possible mechanisms of formation, and clinical relevance of tumor deposits (TDs) in different organs and parts of the body. It also describes the diagnostic features that are currently available for TDs and discusses the prognostic impact of TDs. The poor prognostic and predictive values of TDs were found to be as strong as distant metastasis in different series.  TDs, best characterized by colorectal cancer, are irregular discrete tumor masses that are discontinuous from the leading edge of the tumor. However, even in colorectal cancers, the place of TDs in tumor staging (tumor, lymph node and distant metastasis categories) remains controversial. This book presents the possible mechanisms of TD formation, including neurotrophic and angiotrophic extravascular migratory metastasis, in comparison with the well-known mechanisms of metastasis. It also shows that TDs were identified in esophageal, gastric, salivary gland, head and neck, and breast carcinomas. The possible mechanisms leading to the frequent association of TDs and peritoneal carcinomatosis are discussed.  This is a valuable resource for pathologists, oncologists, and surgeons who are looking for detailed information on the latest scientific insights into the pathology and prognostic implications of TDs.


Book
Biomarkers in carcinoma of unknown primary
Authors: --- ---
ISBN: 3030844315 3030844323 Year: 2022 Publisher: Cham, Switzerland : Springer,

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Keywords

Biochemical markers. --- Neoplasms, Unknown Primary. --- Biomarkers, Tumor. --- Carcinoma. --- Epithelial Tumors, Malignant --- Malignant Epithelial Neoplasms --- Neoplasms, Malignant Epithelial --- Carcinoma, Anaplastic --- Carcinoma, Spindle-Cell --- Carcinoma, Undifferentiated --- Carcinomatosis --- Epithelial Neoplasms, Malignant --- Epithelioma --- Anaplastic Carcinoma --- Anaplastic Carcinomas --- Carcinoma, Spindle Cell --- Carcinomas --- Carcinomatoses --- Epithelial Neoplasm, Malignant --- Epithelial Tumor, Malignant --- Epitheliomas --- Malignant Epithelial Neoplasm --- Malignant Epithelial Tumor --- Malignant Epithelial Tumors --- Neoplasm, Malignant Epithelial --- Spindle-Cell Carcinoma --- Spindle-Cell Carcinomas --- Tumor, Malignant Epithelial --- Undifferentiated Carcinoma --- Undifferentiated Carcinomas --- Biochemical Tumor Markers --- Biological Tumor Marker --- Biological Tumor Markers --- Biomarkers, Cancer --- Marker, Biochemical Tumor --- Marker, Biologic Tumor --- Marker, Biological Tumor --- Marker, Neoplasm Metabolite --- Marker, Tumor Metabolite --- Markers, Biochemical Tumor --- Markers, Biological Tumor --- Markers, Neoplasm Metabolite --- Markers, Tumor Metabolite --- Metabolite Markers, Tumor --- Neoplasm Metabolite Markers --- Tumor Markers, Biologic --- Tumor Metabolite Marker --- Biochemical Tumor Marker --- Cancer Biomarker --- Carcinogen Markers --- Markers, Tumor --- Metabolite Markers, Neoplasm --- Tumor Biomarker --- Tumor Marker --- Tumor Markers, Biochemical --- Tumor Markers, Biological --- Biologic Tumor Marker --- Biologic Tumor Markers --- Biomarker, Cancer --- Biomarker, Tumor --- Cancer Biomarkers --- Marker, Tumor --- Markers, Biologic Tumor --- Markers, Carcinogen --- Metabolite Marker, Neoplasm --- Metabolite Marker, Tumor --- Neoplasm Metabolite Marker --- Tumor Biomarkers --- Tumor Marker, Biochemical --- Tumor Marker, Biologic --- Tumor Marker, Biological --- Tumor Markers --- Tumor Metabolite Markers --- Neoplasm Proteins --- Unknown Primary Neoplasm Metastasis --- Unknown Primary Neoplasms --- Neoplasm Metastasis, Unknown Primary --- Neoplasms, Occult Primary --- Occult Primary Neoplasms --- Unknown Primary Tumors --- Neoplasm, Occult Primary --- Neoplasm, Unknown Primary --- Occult Primary Neoplasm --- Primary Neoplasm, Occult --- Primary Neoplasm, Unknown --- Primary Neoplasms, Occult --- Primary Neoplasms, Unknown --- Primary Tumor, Unknown --- Primary Tumors, Unknown --- Tumor, Unknown Primary --- Tumors, Unknown Primary --- Unknown Primary Neoplasm --- Unknown Primary Tumor --- Biologic markers --- Biological markers --- Biomarkers --- Markers, Biochemical --- Biochemistry --- Indicators (Biology) --- Càncer --- Marcadors bioquímics


Digital
Biomarkers in Carcinoma of Unknown Primary
Authors: --- ---
ISBN: 9783030844325 9783030844318 9783030844332 9783030844349 Year: 2022 Publisher: Cham Springer International Publishing

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Abstract

This book aims to examine all immunohistochemical and molecular pathological biomarkers that can be useful and effective in patient diagnosis, prognosis and treatment decision, especially when faced with a carcinoma of unknown primary. For this purpose, epithelial malignancies of all systems and related biomarkers are examined one by one, and to look at the subject through the metastatic regions window, biomarkers that can be used to determine the primary focus for carcinomas seen in the areas most frequently metastasized are emphasized. With this bi-directional perspective, the reader is able to find biomarkers of any type of carcinoma on a system basis, as well as access to which biomarkers can be used when faced with a metastatic carcinoma. The importance of biomarkers in patient follow-up and treatment is also conveyed through the clinician's eye, and so biomarkers are handled with a holistic approach in all aspects. This book primarily targets pathologists, as well as clinicians (oncologists and surgeons) who manage cancer patients.


Book
Biomarkers in Carcinoma of Unknown Primary
Authors: --- --- ---
ISBN: 9783030844325 Year: 2022 Publisher: Cham Springer International Publishing :Imprint: Springer

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Abstract

Keywords

Biochemical markers. --- Neoplasms, Unknown Primary. --- Biomarkers, Tumor. --- Carcinoma. --- Biologic markers --- Biological markers --- Biomarkers --- Markers, Biochemical --- Biochemistry --- Indicators (Biology) --- Biochemical Tumor Markers --- Biological Tumor Marker --- Biological Tumor Markers --- Biomarkers, Cancer --- Marker, Biochemical Tumor --- Marker, Biologic Tumor --- Marker, Biological Tumor --- Marker, Neoplasm Metabolite --- Marker, Tumor Metabolite --- Markers, Biochemical Tumor --- Markers, Biological Tumor --- Markers, Neoplasm Metabolite --- Markers, Tumor Metabolite --- Metabolite Markers, Tumor --- Neoplasm Metabolite Markers --- Tumor Markers, Biologic --- Tumor Metabolite Marker --- Biochemical Tumor Marker --- Cancer Biomarker --- Carcinogen Markers --- Markers, Tumor --- Metabolite Markers, Neoplasm --- Tumor Biomarker --- Tumor Marker --- Tumor Markers, Biochemical --- Tumor Markers, Biological --- Biologic Tumor Marker --- Biologic Tumor Markers --- Biomarker, Cancer --- Biomarker, Tumor --- Cancer Biomarkers --- Marker, Tumor --- Markers, Biologic Tumor --- Markers, Carcinogen --- Metabolite Marker, Neoplasm --- Metabolite Marker, Tumor --- Neoplasm Metabolite Marker --- Tumor Biomarkers --- Tumor Marker, Biochemical --- Tumor Marker, Biologic --- Tumor Marker, Biological --- Tumor Markers --- Tumor Metabolite Markers --- Neoplasm Proteins --- Unknown Primary Neoplasm Metastasis --- Unknown Primary Neoplasms --- Neoplasm Metastasis, Unknown Primary --- Neoplasms, Occult Primary --- Occult Primary Neoplasms --- Unknown Primary Tumors --- Neoplasm, Occult Primary --- Neoplasm, Unknown Primary --- Occult Primary Neoplasm --- Primary Neoplasm, Occult --- Primary Neoplasm, Unknown --- Primary Neoplasms, Occult --- Primary Neoplasms, Unknown --- Primary Tumor, Unknown --- Primary Tumors, Unknown --- Tumor, Unknown Primary --- Tumors, Unknown Primary --- Unknown Primary Neoplasm --- Unknown Primary Tumor --- Epithelial Tumors, Malignant --- Malignant Epithelial Neoplasms --- Neoplasms, Malignant Epithelial --- Carcinoma, Anaplastic --- Carcinoma, Spindle-Cell --- Carcinoma, Undifferentiated --- Carcinomatosis --- Epithelial Neoplasms, Malignant --- Epithelioma --- Anaplastic Carcinoma --- Anaplastic Carcinomas --- Carcinoma, Spindle Cell --- Carcinomas --- Carcinomatoses --- Epithelial Neoplasm, Malignant --- Epithelial Tumor, Malignant --- Epitheliomas --- Malignant Epithelial Neoplasm --- Malignant Epithelial Tumor --- Malignant Epithelial Tumors --- Neoplasm, Malignant Epithelial --- Spindle-Cell Carcinoma --- Spindle-Cell Carcinomas --- Tumor, Malignant Epithelial --- Undifferentiated Carcinoma --- Undifferentiated Carcinomas

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