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Robust control mechanisms customarily require knowledge of the system’s describing equations which may be of the high order differential type.  In order to produce these equations, mathematical models can often be derived and correlated with measured dynamic behavior.  There are two flaws in this approach one is the level of inexactness introduced by linearizations and the other when no model is apparent.  Several years ago a new genre of control systems came to light that are much less dependent on differential models such as fuzzy logic and genetic algorithms. Both of these soft computing solutions require quite considerable a priori system knowledge to create a control scheme and sometimes complicated training program before they can be implemented in a real world dynamic system. Michie and Chambers’ BOXES methodology created a black box system that was designed to control a mechanically unstable system with very little a priori system knowledge, linearization or approximation.  All the method needed was some notion of maximum and minimum values for the state variables and a set of boundaries that divided each variable into an integer state number.  The BOXES Methodology applies the method to a variety of systems including continuous and chaotic dynamic systems, and discusses how it may be possible to create a generic control method that is self organizing and adaptive that learns with the assistance of near neighbouring states. The BOXES Methodology introduces students at the undergraduate and master’s level to black box dynamic system control , and gives lecturers access to background materials that can be used in their courses in support of student research and classroom presentations in novel control systems and real-time applications of artificial intelligence. Designers are provided with a novel method of optimization and controller design when the equations of a system are difficult or unknown. Researchers interested in artificial intelligence (AI) research and models of the brain and practitioners from other areas of biology and technology are given an insight into how AI software can be written and adapted to operate in real-time.

Automatic control. --- Machine learning. --- Microprogramming. --- Mechanical Engineering --- Engineering & Applied Sciences --- Mechanical Engineering - General --- Industrial & Management Engineering --- Artificial intelligence. --- Learning, Machine --- AI (Artificial intelligence) --- Artificial thinking --- Electronic brains --- Intellectronics --- Intelligence, Artificial --- Intelligent machines --- Machine intelligence --- Thinking, Artificial --- Engineering. --- System theory. --- Algorithms. --- Vibration. --- Dynamical systems. --- Dynamics. --- Control engineering. --- Control. --- Vibration, Dynamical Systems, Control. --- Control Structures and Microprogramming. --- Systems Theory, Control. --- Artificial Intelligence (incl. Robotics). --- Bionics --- Cognitive science --- Digital computer simulation --- Electronic data processing --- Logic machines --- Machine theory --- Self-organizing systems --- Simulation methods --- Fifth generation computers --- Neural computers --- Artificial intelligence --- Systems theory. --- Control and Systems Theory. --- Artificial Intelligence. --- Computer programming --- Algorism --- Algebra --- Arithmetic --- Cycles --- Mechanics --- Sound --- Foundations --- Microprogramming . --- Systems, Theory of --- Systems science --- Science --- Dynamical systems --- Kinetics --- Mathematics --- Mechanics, Analytic --- Force and energy --- Physics --- Statics --- Control engineering --- Control equipment --- Control theory --- Engineering instruments --- Automation --- Programmable controllers --- Philosophy

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Classical mechanics. Field theory --- Engineering sciences. Technology --- Computer science --- Programming --- Computer architecture. Operating systems --- Artificial intelligence. Robotics. Simulation. Graphics --- machinetalen --- programmeren (informatica) --- systeemtheorie --- controleleer --- algoritmen --- KI (kunstmatige intelligentie) --- systeembeheer --- robots --- dynamica

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Nuclear Receptors are inducible transcription factors that mediate complex effects on development, differentiation and homeostasis. They regulate the transcription of their target genes through binding to DNA sequences.*Analysis of Nuclear Receptor Ligands*Structure/Function Analysis of Nuclear Receptors*Analysis of Nuclear Receptor Co-Factors and Chromatin Remodeling

Nuclear receptors (Biochemistry). --- Laboratory Chemicals --- Proteins --- DNA-Binding Proteins --- Investigative Techniques --- Transcription Factors --- Biochemical Phenomena --- Pharmacological Phenomena --- Physiological Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Amino Acids, Peptides, and Proteins --- Specialty Uses of Chemicals --- Chemical Phenomena --- Phenomena and Processes --- Chemical Actions and Uses --- Chemicals and Drugs --- Receptors, Cytoplasmic and Nuclear --- Structure-Activity Relationship --- Models, Animal --- Ligands --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Experimental Animal Models --- Laboratory Animal Models --- Animal Model --- Animal Model, Experimental --- Animal Model, Laboratory --- Animal Models --- Animal Models, Experimental --- Animal Models, Laboratory --- Experimental Animal Model --- Laboratory Animal Model --- Model, Animal --- Model, Experimental Animal --- Model, Laboratory Animal --- Models, Experimental Animal --- Models, Laboratory Animal --- Animal Experimentation --- Relationship, Structure-Activity --- Relationships, Structure-Activity --- Structure Activity Relationship --- Structure-Activity Relationships --- Cytoplasmic Hormone Receptors --- Cytoplasmic Receptors --- Cytosol and Nuclear Receptors --- Intracellular Membrane Receptors --- Nuclear Hormone Receptors --- Nuclear Receptors --- Receptors, Cytoplasmic --- Receptors, Cytosol and Nuclear --- Receptors, Cytosolic and Nuclear --- Receptors, Intracellular Membrane --- Receptors, Nuclear --- Receptors, Nuclear and Cytoplasmic --- Cytoplasmic and Nuclear Receptors --- Cytosolic and Nuclear Receptors --- Hormone Receptors, Cytoplasmic --- Hormone Receptors, Nuclear --- Nuclear and Cytoplasmic Receptors --- Membrane Receptors, Intracellular --- Receptors, Cytoplasmic Hormone --- Receptors, Nuclear Hormone --- Hormones --- Chemical Phenomenon --- Chemical Process --- Physical Chemistry Phenomena --- Physical Chemistry Process --- Physicochemical Phenomenon --- Physicochemical Process --- Chemical Concepts --- Chemical Processes --- Physical Chemistry Concepts --- Physical Chemistry Processes --- Physicochemical Concepts --- Physicochemical Phenomena --- Physicochemical Processes --- Chemical Concept --- Chemistry Process, Physical --- Chemistry Processes, Physical --- Concept, Chemical --- Concept, Physical Chemistry --- Concept, Physicochemical --- Concepts, Chemical --- Concepts, Physical Chemistry --- Concepts, Physicochemical --- Phenomena, Chemical --- Phenomena, Physical Chemistry --- Phenomena, Physicochemical --- Phenomenon, Chemical --- Phenomenon, Physicochemical --- Physical Chemistry Concept --- Physicochemical Concept --- Process, Chemical --- Process, Physical Chemistry --- Process, Physicochemical --- Processes, Chemical --- Processes, Physical Chemistry --- Processes, Physicochemical --- Specialty Chemicals and Products --- Physiological Concepts --- Physiological Phenomenon --- Physiological Process --- Physiological Processes --- Concept, Physiological --- Concepts, Physiological --- Phenomena, Physiological --- Phenomenas, Physiological --- Phenomenon, Physiological --- Physiological Concept --- Process, Physiological --- Processes, Physiological --- Pharmacologic Phenomena --- Pharmacologic Phenomenon --- Pharmacologic Process --- Pharmacological Concepts --- Pharmacological Phenomenon --- Pharmacologic Processes --- Pharmacological Processes --- Concept, Pharmacological --- Concepts, Pharmacological --- Pharmacological Concept --- Phenomena, Pharmacologic --- Phenomena, Pharmacological --- Phenomenon, Pharmacologic --- Phenomenon, Pharmacological --- Process, Pharmacologic --- Processes, Pharmacologic --- Processes, Pharmacological --- Biochemical Concepts --- Biochemical Phenomenon --- Biochemical Process --- Phenomena, Biochemical --- Biochemical Processes --- Biochemical Concept --- Concept, Biochemical --- Concepts, Biochemical --- Phenomenon, Biochemical --- Process, Biochemical --- Processes, Biochemical --- Molecular Biology --- Transcription Factor --- Factor, Transcription --- Factors, Transcription --- Gene Expression Regulation --- Transcription, Genetic --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- DNA Binding Protein --- DNA Single-Stranded Binding Protein --- SS DNA BP --- Single-Stranded DNA-Binding Protein --- DNA Helix Destabilizing Proteins --- Single-Stranded DNA Binding Proteins --- Binding Protein, DNA --- DNA Binding Proteins --- DNA Single Stranded Binding Protein --- DNA-Binding Protein, Single-Stranded --- Single Stranded DNA Binding Protein --- Single Stranded DNA Binding Proteins --- Gene Products, Protein --- Gene Proteins --- Protein Gene Products --- Proteins, Gene --- Molecular Mechanisms of Pharmacological Action --- Chemicals, Laboratory --- Ligand --- Cytoplasmic Receptor --- Nuclear Hormone Receptor --- Nuclear Receptor --- Hormone Receptor, Nuclear --- Receptor, Cytoplasmic --- Receptor, Nuclear --- Receptor, Nuclear Hormone --- DNA-Binding Protein --- Protein, DNA-Binding --- Protein

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Industrial economics --- Business policy --- Japan

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Chemical laboratory practice --- Molecular biology --- genetische manipulatie --- DNA (deoxyribonucleic acid) --- klonen --- moleculaire biologie --- Molecular cloning --- Cloning, Molecular --- Basic Sciences. Biology --- Basic Sciences. Molecular Biology --- Cellular Biology. --- Genetic Engineering. --- molecular cloning --- plasmids --- Bacteriophages --- Electrophoresis --- DNA. --- DNA --- eukaryotic cells --- PCR --- In vitro culture --- RNA. --- RNA --- Sampling --- Tracer techniques --- Nucleotides --- Gene pools --- genes --- identification. --- identification --- genetic engineering --- Mutagens --- gene expression --- Escherichia coli --- cloning --- Transgenic animals --- proteins --- technology --- Biotechnologie --- Klonen --- 57.08 --- 577.2 --- 57.08 Biological techniques. Experimental methods. Equipment --- Biological techniques. Experimental methods. Equipment --- 577.2 Molecular bases of life. Molecular biology --- Molecular bases of life. Molecular biology --- Molecular Cloning --- Cosmids --- Cloning, Organism --- DNA cloning --- Gene cloning --- Cloning --- Genetic engineering --- Molecular genetics --- Clone cells --- Moleculaire genetica --- Clonage moléculaire --- Laboratory Manuals. --- Laboratory manuals. --- Manuels de laboratoire --- Molecular cloning - Laboratory manuals --- Cloning, Molecular - laboratory manuals --- Cloning, molecular --- Electrophoresis, agar gel --- Gene library --- Plasmids --- Rna, messenger