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Hepatocellular carcinoma (HCC) currently ranks as the third most common cause of death. As the primary malignancy of the liver is directly related to an underlying liver condition, its incidence and profile are expected to change soon. While effective prevention programs and antiviral therapies for hepatitis B and C will lower the incidence of HCC, emerging socioeconomic issues will deliver new at-risk populations. Moreover, diagnostic techniques and protocols have undergone significant advancements. Reliance on contrast enhanced ultrasound has been re-evaluated, imaging methods being considered as sufficient diagnostic tools. Molecular characterization remains desirable, since chemotherapeutic agents still have limited applicability. In light of recent diagnostic advancements and novel therapeutic solutions, it is our belief that a comprehensive update on recent paradigm shifts and interesting upcoming developments is highly needed.

Liver --- Cancer. --- Hepatocellular carcinoma --- Medicine --- Gastrointestinal Oncology --- Oncology --- Health Sciences

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This book discusses the various therapeutic agents and pathologies that can have a negative impact on liver function. The profound changes such agents may exert on the liver, an essential organ, can severely alter a patient's metabolism, negatively impacting the course of a disease and thus significantly shortening life expectancy and negatively affecting outcomes. This book provides a comprehensive overview of these selected issues with chapters on epidemiology, pathogenesis, clinical manifestations, diagnostic methods, and treatment options in the context of hepatotoxicity.

Hepatotoxicology. --- Pathologies.

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This book discusses the various therapeutic agents and pathologies that can have a negative impact on liver function. The profound changes such agents may exert on the liver, an essential organ, can severely alter a patient's metabolism, negatively impacting the course of a disease and thus significantly shortening life expectancy and negatively affecting outcomes. This book provides a comprehensive overview of these selected issues with chapters on epidemiology, pathogenesis, clinical manifestations, diagnostic methods, and treatment options in the context of hepatotoxicity.

Hepatotoxicology. --- Pathologies.