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Cancer Immunology is intended as an up-to-date, clinically relevant review of cancer immunology and immunotherapy. The rapid flow of studies in the field of cancer immunology during the last decade has increased our understanding of the interactions between the immune system and cancerous cells. In particular, it is now well known that such interactions result in the induction of epigenetic changes in cancerous cells and the selection of less immunogenic clones as well as alterations in immune responses. Understanding the cross-talk between nascent transformed cells and cells of the immune system has led to the development of combinatorial immunotherapeutic strategies to combat cancer. This volume is focused on interactions between cancerous cells and various components of the innate and adaptive immune system are fully described. Notably, the principal focus is very much on clinical aspects, the aim being to educate clinicians on the clinical implications of the most recent findings and novel developments in the field. This is to be hoped that this translational book will be comprehensible, cogent and of special value for researchers and clinicians who wish to extend their knowledge on cancer immunology. .
Medicine & Public Health. --- Internal Medicine. --- Immunology. --- Oncology. --- Hematology. --- Medicine. --- Internal medicine. --- Médecine --- Immunologie --- Médecine interne --- Hématologie --- Cancérologie --- Medicine --- Health & Biological Sciences --- Internal Medicine --- Cancer --- T cells. --- Immunological aspects. --- Immunotherapy. --- T lymphocytes --- Thymus-dependent cells --- Thymus-dependent lymphocytes --- Thymus-derived cells --- Carcinogenesis --- Immunological aspects --- Lymphocytes --- Treatment --- Oncology . --- Haematology --- Internal medicine --- Blood --- Tumors --- Immunobiology --- Life sciences --- Serology --- Medicine, Internal --- Diseases
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This translational book describes in detail the clinical application of novel approaches in cancer immunotherapy with the aim of educating clinicians in the implications of the most recent research and new developments in the field. The scope is broad, encompassing, for example, prognostic biomarkers for personalized cancer treatment, strategies for targeting tumor immunosuppression, gene therapy, virus-based vaccines, targeting of cancer stem cells, hematopoietic stem cell transplantation, the role of T lymphocytes in cancer immunotherapy, use of monoclonal antibodies, and many more innovative approaches. Clinical immunologists, hematologists, and oncologists in particular will find the book to be of value in expanding their knowledge. The book is the second in a three-volume series, Cancer Immunology, which offers an up-to-date review of cancer immunology and immunotherapy. The remaining volumes focus on the immunopathology of cancers and cancer immunotherapy for organ-specific tumors. In total the series, designed for both clinicians and researchers, includes contributions from more than 250 scientists working at leading universities and institutes from across the world.
Medicine & Public Health. --- Internal Medicine. --- Immunology. --- Oncology. --- Medicine. --- Internal medicine. --- Médecine --- Immunologie --- Médecine interne --- Cancérologie --- Medicine --- Health & Biological Sciences --- Internal Medicine --- Cancer --- Immunological aspects. --- Treatment. --- Carcinogenesis --- Cancer therapy --- Cancer treatment --- Immunological aspects --- Therapy --- Oncology . --- Tumors --- Immunobiology --- Life sciences --- Serology --- Medicine, Internal
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Cancer Immunology is intended as an up-to-date, clinically relevant review of cancer immunology and immunotherapy. This volume focuses on the immunopathology and immunotherapy of organ cancers in detail. It clearly explains their immunology and describes novel immunotherapy for specific cancers, including pediatric solid tumors, hematologic malignancies, gastrointestinal tumors, skin cancers, bone and connective tissue tumors, central nervous system tumors, lung cancers, genitourinary tract tumors, and breast cancers. In so doing, it builds on the previous two volumes in Cancer Immunology, placing basic knowledge on tumor immunology and immunotherapy into a clinical perspective with the aim of educating clinicians on advances in cancer immunology and the most recent approaches in the immunotherapy of various tumors. This translational, clinically oriented book will be of special value to clinical immunologists, hematologists, and oncologists.
Medicine & Public Health. --- Internal Medicine. --- Immunology. --- Oncology. --- Medicine. --- Internal medicine. --- Médecine --- Immunologie --- Médecine interne --- Cancérologie --- Medicine --- Health & Biological Sciences --- Internal Medicine --- Cancer --- Immunotherapy. --- Immunological aspects --- Treatment --- Oncology . --- Tumors --- Immunobiology --- Life sciences --- Serology --- Medicine, Internal
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This book comprises a collection of case-based chapters, submitted by physicians and pediatricians in all specialties and meticulously refined and selected to cover the most common and important aspects of Pediatric Allergy knowledge. Commonly encountered disorders such as allergic rhinitis, food allergy, and atopic dermatitis are covered among many others. Each chapter starts with a brief of the initial presentation and lab data of the patient, followed by a series of 3-6 multiple choice questions (MCQs), leading the reader to the diagnosis and best of practice in a step-wise manner. Clinical pearls presented as "practical points", and the MCQ format along with detailed answers, makes Pediatrc Allergy an essential reading material that a pediatric allergologist cannot afford to miss.
Allergy in children. --- Pediatrics. --- Allergy. --- Emerging infectious diseases. --- Immunology. --- Allergology. --- Infectious Diseases. --- Immunobiology --- Life sciences --- Serology --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunologic diseases --- Immunoglobulin E --- Paediatrics --- Pediatric medicine --- Medicine --- Children --- Diseases --- Health and hygiene --- Infectious diseases. --- Immunologic diseases. --- Hypersensitivity. --- Immune System Diseases --- Pediatrics --- Child. --- Diseases of Immune System --- Immune Diseases --- Immunological Diseases --- Immune Disorders --- Immune System Disorders --- Immunologic Diseases --- Disease, Immune --- Disease, Immune System --- Disease, Immunologic --- Disease, Immunological --- Disorder, Immune System --- Immune Disease --- Immune Disorder --- Immune System Disease --- Immune System Disorder --- Immunologic Disease --- Immunological Disease --- Allergic Reaction --- Allergy --- Allergic Reactions --- Hypersensitivities --- Reaction, Allergic --- Reactions, Allergic --- Immune diseases --- Immune disorders --- Immune system --- Immunologic disorders --- Immunological diseases --- Immunologic diseases in children --- Pediatric allergy --- Minors --- Diseases. --- Human beings --- Illness --- Illnesses --- Morbidity --- Sickness --- Sicknesses --- Epidemiology --- Health --- Pathology --- Sick
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This book comprises a collection of categorized case-based questions, directed and meticulously selected to cover the most common and most important aspects of immunodeficiency diseases. Immunodeficiency disorders of infancy and childhood such as antibody deficiencies, phagocyte defects and defects in innate immunity are addressed among others. Each chapters starts with a brief of the initial presentation and lab data of the patient, followed by a series of 5-6 multiple choice questions (MCQs), leading the reader to the diagnosis and best of practice in a step-wise manner. This MCQ format along with precise, yet detailed answer ensures a quick, case-based, reality learning to the reader. This comprehensive MCQ series, is an essential reading material that a pediatric clinician, hematologist, immunologist, transplant specialist, or pulmonologist, can not afford to miss.
Pediatrics. --- Hematology. --- Immunology. --- Immunobiology --- Life sciences --- Serology --- Haematology --- Internal medicine --- Blood --- Paediatrics --- Pediatric medicine --- Medicine --- Children --- Diseases --- Health and hygiene --- Immunological deficiency syndromes in children. --- Immunologic diseases in children
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This book focusing on the immunopathology of cancers is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Readers will find detailed descriptions of the interactions between cancerous cells and various components of the innate and adaptive immune system. The principal focus, however, is very much on clinical aspects, the aim being to educate clinicians in the clinical implications of the latest research and novel developments in the field. In the new edition of this very well received book, first published in 2015, the original chapters have been significantly updated and additional chapters included on, for example, current knowledge on the roles of T-helper cells and NK cells in tumor immunity, the part played by oncoviruses in the development of various cancers, and the applications of fluorescent in situ hybridization, bioluminescence, and cancer molecular and functional imaging. Cancer Immunology: A Translational Medicine Context will be of special value to clinical immunologists, hematologists, and oncologists.
Oncology . --- Immunology. --- Hematology. --- Oncology. --- Haematology --- Internal medicine --- Blood --- Immunobiology --- Life sciences --- Serology --- Tumors --- Diseases --- Cancer --- Immunological aspects. --- Carcinogenesis --- Immunological aspects
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Thymus. --- Thymus gland --- Endocrine glands --- Lymphoid tissue
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Cell receptors. --- Proteins. --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Cell membrane receptors --- Cell surface receptors --- Receptors, Cell --- Binding sites (Biochemistry) --- Cell membranes --- Proteins
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This translational, clinically oriented book describes in detail novel approaches to cancer immunotherapy, current strategies to target tumor immunosuppression, and prognostic biomarkers for personalized cancer treatments. Since the first, very successful edition of the book was published in 2015, the original chapters have been significantly updated and entirely new chapters are included on, for example, cancer immunoprevention, aptamer-mediated cancer gene therapy, haploidentical bone marrow transplantation for pediatric malignancies, and nanoimmunotherapy. The book is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Other volumes in the series address the translational medicine context and cancer immunotherapy for organ-specific tumors. Cancer Immunology: Bench to Bedside Immunotherapy of Cancers will be of special value to clinical immunologists, hematologists, and oncologists. .
Cancer --- Neoplasms --- Immunotherapy. --- Immunological aspects. --- therapy. --- Oncology . --- Immunology. --- Internal medicine. --- Oncology. --- Internal Medicine. --- Medicine, Internal --- Medicine --- Immunobiology --- Life sciences --- Serology --- Tumors --- Carcinogenesis --- Immunological aspects
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This book explains the immunology of organ-specific malignancies and discusses novel immunotherapy strategies for their treatment. Since the first, very successful edition of the book was published in 2015, a number of entirely new chapters have been included. The range of cancers considered has accordingly been extended, with coverage of the latest immunotherapy approaches for skin cancers, ocular malignancies, endocrine malignancies, cardiac cancers, vascular cancers, and HPV-associated cancers. In addition, the original chapters have been updated to document the latest advances in immunotherapy for pediatric solid tumors, hematologic malignancies, gastrointestinal tumors, bone tumors, CNS tumors, lung cancer, genitourinary tract tumors, and breast cancer, among others. The book is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Other volumes in the series address the translational medicine context and bench to bedside immunotherapy. Cancer Immunology: Cancer Immunotherapy for Organ-Specific Tumors will be of special value to clinical immunologists, hematologists, and oncologists. .
Oncology . --- Internal medicine. --- Immunology. --- Oncology. --- Internal Medicine. --- Immunobiology --- Life sciences --- Serology --- Medicine, Internal --- Medicine --- Tumors --- Cancer --- Immunotherapy. --- Immunological aspects. --- Carcinogenesis --- Immunological aspects --- Treatment
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