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This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.

Drug discrimination (Pharmacology). --- Drug therapy. --- Pharmacological phenomena. --- Pharmacology -- Sex differences. --- Sex factors. --- Drug discrimination (Pharmacology) --- Epidemiologic Factors --- Therapeutics --- Physiological Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Phenomena and Processes --- Quality of Health Care --- Public Health --- Environment and Public Health --- Health Care Quality, Access, and Evaluation --- Health Care --- Sex Factors --- Drug Therapy --- Pharmacological Phenomena --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Pharmacology --- Medical care --- Sex differences. --- Delivery of health care --- Delivery of medical care --- Health care --- Health care delivery --- Health services --- Healthcare --- Medical and health care industry --- Medical services --- Personal health services --- Drug effects --- Medical pharmacology --- Medicine. --- Molecular biology. --- Pharmacology. --- Pharmaceutical technology. --- Biomedicine. --- Pharmacology/Toxicology. --- Molecular Medicine. --- Pharmaceutical Sciences/Technology. --- Public health --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect --- Toxicology. --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Medicine --- Poisoning --- Poisons --- Toxicology --- Health Workforce --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology

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Prior to 2000, gender medicine was not a popular term, but in the past 10 years and analogous to the growth in the need to consider Personalised Medicine, it has become hugely important to understand that “women are not small men”. There is no more doubt that clinical manifestations of prevalent diseases differ in women and men and this is at least partially due to sex differences in pathophysiology. While the majority of diagnostic and therapeutic strategies were aimed at males 30 years ago, endocrine and reproductive systems were the logical areas for the observation of the effects of gender on medicine. It has been know for some time that women and men also differ in diseases such as diabetes and various cardiovascular syndromes, which has pushed research in these directions. Nevertheless, it is still a challenge to define gender medicine clearly, since it is characterized by an unbiased comparison between women and men and the inclusion of gender as a sociocultural process into medical hypotheses. It includes the recognition of biological differences among women and men, i.e. sex differences, but goes well beyond this.   Sex and Gender Aspects in Clinical Medicine defines the concepts and practical clinical meaning of gender medicine. As such it is a highly complex yet hugely important reference for all professional medical personnel, from clinicians in cardiology, endocrinology, oncology, reproductive medicine, diabetology, rheumatology, plus also a number of specialists who deal with pharmacotherapy, pathophysiology, genomics, as well as researchers investigating any of the above disciplines. Many medical authors use gender as an inclusive term that can include the biological notion of sex as well as the sociocultural notion of gender. In this book, the Editors use sex and gender in their more stringent sense. If a clear distinction is not possible gender is used in a broader sense to include biological phenomena   The US Institute of Medicine declared in its 2001 and 2010 statements that being a woman or being a man significantly influences the course of diseases. Gender medicine aims at better management and treatment of both women and men, and this book is an ideal reference for anyone wanting to understand the intricate relationship between gender and health.

Clinical medicine. --- Clinical Medicine -- methods. --- Geschlechtsunterschied. --- Klinische Medizin. --- Men’s Health. --- Sex Factors. --- Women’s Health. --- Clinical medicine --- Health --- Epidemiologic Factors --- Investigative Techniques --- Medicine --- Health Occupations --- Public Health --- Quality of Health Care --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Population Characteristics --- Environment and Public Health --- Health Care Quality, Access, and Evaluation --- Disciplines and Occupations --- Health Care --- Sex Factors --- Men's Health --- Women's Health --- Clinical Medicine --- Methods --- Health & Biological Sciences --- Pathology --- Internal Medicine --- Sex factors in disease --- Research. --- Medicine, Clinical --- Diseases --- Sex differences --- Sex factors --- Medicine. --- Internal medicine. --- Medicine & Public Health. --- Internal Medicine. --- Medicine, Internal

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Prior to 2000, gender medicine was not a popular term, but in the past 10 years and analogous to the growth in the need to consider Personalised Medicine, it has become hugely important to understand that women are not small men . There is no more doubt that clinical manifestations of prevalent diseases differ in women and men and this is at least partially due to sex differences in pathophysiology. While the majority of diagnostic and therapeutic strategies were aimed at males 30 years ago, endocrine and reproductive systems were the logical areas for the observation of the effects of gender on medicine. It has been know for some time that women and men also differ in diseases such as diabetes and various cardiovascular syndromes, which has pushed research in these directions. Nevertheless, it is still a challenge to define gender medicine clearly, since it is characterized by an unbiased comparison between women and men and the inclusion of gender as a sociocultural process into medical hypotheses. It includes the recognition of biological differences among women and men, i.e. sex differences, but goes well beyond this.   Sex and Gender Aspects in Clinical Medicine defines the concepts and practical clinical meaning of gender medicine. As such it is a highly complex yet hugely important reference for all professional medical personnel, from clinicians in cardiology, endocrinology, oncology, reproductive medicine, diabetology, rheumatology, plus also a number of specialists who deal with pharmacotherapy, pathophysiology, genomics, as well as researchers investigating any of the above disciplines. Many medical authors use gender as an inclusive term that can include the biological notion of sex as well as the sociocultural notion of gender. In this book, the Editors use sex and gender in their more stringent sense. If a clear distinction is not possible gender is used in a broader sense to include biological phenomena   The US Institute of Medicine declared in its 2001 and 2010 statements that being a woman or being a man significantly influences the course of diseases. Gender medicine aims at better management and treatment of both women and men, and this book is an ideal reference for anyone wanting to understand the intricate relationship between gender and health.

geneeskunde --- Human medicine --- Clinical Medicine --- Men's Health. --- Sex Factors. --- Women's Health. --- Clinical medicine. --- Sex factors in disease --- Médecine clinique --- Maladies --- methods. --- Facteurs sexuels --- EPUB-LIV-FT LIVMEDEC SPRINGER-B