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This book focuses on the envelope of Gram-positive bacteria including its composition, the latest discoveries in the mechanisms behind its assembly, and its role in pathogenesis. Furthermore, new applications in biotechnology and vaccine development involving these bacteria are discussed in detail. This concise volume consists of eleven chapters by prominent experts in the field, which review the latest findings and current state of knowledge on a range of diverse yet interlinked aspects. This book is written for all researchers, clinicians and technicians engaged in basic or applied science projects on Gram-positive bacteria. .
Medicine. --- Medical microbiology. --- Molecular biology. --- Medical biochemistry. --- Biomedicine. --- Medical Microbiology. --- Medical Biochemistry. --- Molecular Medicine. --- Gram-positive bacterial infections. --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Pathology --- Molecular biochemistry --- Molecular biophysics --- Biophysics --- Biomolecules --- Systems biology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Physicians --- Bacterial diseases --- Microbiology. --- Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Microbial biology --- Microorganisms --- Composition --- Health Workforce --- Clinical biochemistry. --- Medicine --- Biomedical Research. --- Research. --- Biological research --- Biomedical research
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Many bacteria, animals, and plants produce toxins that can prove lethal to other organisms. Toxins are a form of "biological warfare" that helps their producer to survive and so confer an evolutionary advantage. They display an extraordinary range of complexity, from the formic acid provided by ants to bacterial proteins composed of thousands of amino acids. This Guidebook considers the more complex protein and peptide toxins and groups them according to their mode of action. Topics covered include: membrane-permeabilizing toxins; toxins affecting signal transduction and protein synthesis; cytoskeleton-affecting toxins; toxins affecting the immune and inflammatory response. This class of biomolecules will be of interest to a wide range of researchers in cell biology, neuroscience, and toxicology.
Toxins --- Handbooks, manuals, etc. --- Handbooks, manuals, etc --- Natural toxicants --- Toxicants, Natural --- Toxins and antitoxins --- Antigens --- Metabolites --- Poisons --- Antitoxins --- Detoxification (Health)
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Many bacteria, animals, and plants produce toxins that can prove lethal to other organisms. Toxins are a form of "biological warfare" that helps their producer to survive and so confer an evolutionary advantage. They display an extraordinary range of complexity, from the formic acid provided by ants to bacterial proteins composed of thousands of amino acids. This Guidebook considers the more complex protein and peptide toxins and groups them according to their mode of action.; Topics covered include: membrane-permeabilizing toxins; toxins affecting signal transduction and protein synthesis; cytoskeleton-affecting toxins; toxins affecting the immune and inflammatory response. This class of biomolecules will be of interest to a wide range of researchers in cell biology,; neuroscience, and toxicology.
Toxins. --- Natural toxicants --- Toxicants, Natural --- Toxins and antitoxins --- Antigens --- Metabolites --- Poisons --- Antitoxins --- Detoxification (Health) --- Toxins - Handbooks, manuals, etc.
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This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.
Medicine --- Research. --- Health Workforce --- Immunology. --- Cancer. --- Regenerative medicine. --- Stem cells. --- Cytology --- Cancer Biology. --- Regenerative Medicine and Tissue Engineering. --- Stem Cell Biology. --- Cytological Techniques. --- Enginyeria biomèdica --- Organogènesi --- Investigació mèdica --- Technique. --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells --- Regeneration (Biology) --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors --- Immunobiology --- Life sciences --- Serology
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Vaccines. --- Drug development. --- Vaccines. --- Drug Design.
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This book focuses on the envelope of Gram-positive bacteria including its composition, the latest discoveries in the mechanisms behind its assembly, and its role in pathogenesis. Furthermore, new applications in biotechnology and vaccine development involving these bacteria are discussed in detail. This concise volume consists of eleven chapters by prominent experts in the field, which review the latest findings and current state of knowledge on a range of diverse yet interlinked aspects. This book is written for all researchers, clinicians and technicians engaged in basic or applied science projects on Gram-positive bacteria. .
General microbiology --- General biochemistry --- Molecular biology --- Human biochemistry --- Medical microbiology, virology, parasitology --- Pathological biochemistry --- Human medicine --- medische microbiologie --- biochemie --- geneeskunde --- microbiologie --- biotechnologie --- vaccinatie --- moleculaire biologie
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Vaccines --- Drug development --- Vaccines. --- Biomedical Research. --- Drug Design. --- Immunity, Active. --- Vaccination. --- Drug development. --- Vaccines --- Vaccins. --- Vaccination. --- Médicaments --- Médicaments --- Immunité. --- Research --- Research. --- Mise au point. --- Conception.
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The threat constituted by the multiple outbreaks of avian influenza during the last few years is urgently calling for the development of new influenza vaccines. Fortunately, a quantum leap in technology has revolutionized the study of influenza and the engineering of new vaccine strains by reverse genetics. This volume provides a historical background and state-of-the-art information about the recent advances in the biology of influenza and the design of new influenza vaccines.
Influenza vaccines. --- Influenza. --- Influenza viruses. --- Orthomyxoviruses --- Flu --- Flu, Respiratory --- Grippe --- Respiratory flu --- Respiratory infections --- Virus diseases --- Influenza virus vaccines --- Viral vaccines --- Medical virology. --- Life sciences. --- Virology. --- Life Sciences, general. --- Biosciences --- Sciences, Life --- Science --- Medical microbiology --- Virology --- Microbiology
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The emergence of H5N1 avian influenza in 1997 and of the influenza A H1N1 of swine origin in 2009 calls for new, rapid and sustainable solutions for both seasonal and pandemic influenza viruses. During the last ten years, science and technology have made enormous progress, and we are now able to monitor in real time the genetics of viruses while they spread globally, to make more powerful vaccines using novel adjuvants, and to generate viruses in the laboratory using reverse genetics. This volume not only provides state-of-the-art information on the biology of influenza viruses and on influenza vaccines, but is also designed to be a resource to face the present H1N1 pandemic and to plan for long-term global and sustainable solutions.
Influenza A virus -- Immunology. --- Influenza B virus -- Immunology. --- Influenza Vaccines -- Therapeutic use. --- Influenza vaccines. --- Influenza viruses. --- Influenza, Human. --- Influenza vaccines --- Influenza --- Influenza viruses --- Orthomyxoviridae Infections --- Influenza A virus --- Respiratory Tract Infections --- Viral Vaccines --- Respiratory Tract Diseases --- Vaccines --- RNA Virus Infections --- Influenzavirus A --- Influenza A Virus, H1N1 Subtype --- Influenza Vaccines --- Influenza, Human --- Orthomyxoviridae --- Virus Diseases --- Diseases --- Biological Products --- RNA Viruses --- Complex Mixtures --- Chemicals and Drugs --- Vertebrate Viruses --- Viruses --- Organisms --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Influenza. --- Flu --- Flu, Respiratory --- Grippe --- Respiratory flu --- Influenza virus vaccines --- Medicine. --- Virology. --- Life sciences. --- Biomedicine. --- Life Sciences, general. --- Orthomyxoviruses --- Respiratory infections --- Virus diseases --- Viral vaccines --- Medical virology. --- Biosciences --- Sciences, Life --- Science --- Medical microbiology --- Virology --- Microbiology
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Biology --- Medical microbiology, virology, parasitology --- biologie --- virologie --- influenza --- vaccinatie
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