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Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leading NSAID in over 50 countries worldwide. This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including comparisons with anti-inflammatory, analgesic and antipyretic agents. The emphasis is on the action of nimesulide in relation to its therapeutic and side effects in comparison with other established NSAIDs, including the new class of Coxibs. The chapters are written by leading experts and cover development of nimesulide, including synthesis and production, introduction, and approved uses and applications, followed by pharmacokinetics and toxicological properties, adverse reactions and their mechanisms.

Nimesulide. --- Pharmacology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect --- Analgesics --- Antipyretics --- Cyclooxygenase 2 --- Nonsteroidal anti-inflammatory agents --- Sulfonamides --- Inhibitors --- Toxicology. --- Pain Medicine. --- Rheumatology. --- Immunology. --- Human physiology. --- Anesthesiology. --- Pharmacology/Toxicology. --- Human Physiology. --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Anaesthesiology --- Surgery --- Human biology --- Physiology --- Human body --- Immunobiology --- Life sciences --- Serology --- Internal medicine --- Connective tissues --- Joints --- Toxicology --- Diseases --- Algiatry --- Pain medicine.

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Salicylates --- Aspirin --- Aspirin. --- 2-(Acetyloxy)benzoic Acid --- Acetysal --- Acylpyrin --- Aloxiprimum --- Colfarit --- Dispril --- Easprin --- Ecotrin --- Endosprin --- Magnecyl --- Micristin --- Polopirin --- Polopiryna --- Solprin --- Solupsan --- Zorprin --- Acetylsalicylic Acid --- Acid, Acetylsalicylic --- pharmacology. --- Acetylsalicylic acid --- Analgesics --- Nonsteroidal anti-inflammatory agents --- Salicylic acid --- pharmacology --- Salicylates. --- Benzoates

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Immunology. Immunopathology --- Human physiology --- Anesthesiology --- Pharmacology. Therapy --- Pathology of the organs of movement --- immunologie --- farmacologie --- anesthesie --- toxicologie --- reumatologie --- analgesie --- pijn --- fysiologie

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• Reference Manager
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Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leading NSAID in over 50 countries worldwide. This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including comparisons with anti-inflammatory, analgesic and antipyretic agents. The emphasis is on the action of nimesulide in relation to its therapeutic and side effects in comparison with other established NSAIDs, including the new class of Coxibs. The chapters are written by leading experts and cover development of nimesulide, including synthesis and production, introduction, and approved uses and applications, followed by pharmacokinetics and toxicological properties, adverse reactions and their mechanisms.

Immunology. Immunopathology --- Human physiology --- Anesthesiology --- Pharmacology. Therapy --- Pathology of the organs of movement --- immunologie --- farmacologie --- anesthesie --- toxicologie --- reumatologie --- analgesie --- pijn --- fysiologie