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Theatrical science --- anno 500-1499 --- 82-251 --- German drama --- -Religious drama, German --- -Mysteries and miracle plays, German --- -Theater --- -Dramatics --- Histrionics --- Professional theater --- Stage --- Theatre --- Performing arts --- Acting --- Actors --- German miracle-plays --- German mysteries and miracle-plays --- German religious drama --- German literature --- Religieus toneel --- History and criticism --- History --- -German drama --- Mysteries and miracle plays, German --- Religious drama, German --- Theater --- History and criticism. --- -Religieus toneel --- -82-251 --- 82-251 Religieus toneel --- Dramatics
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Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, long-term application of this program leads to typical disease sequelae such as fatigue / depressive symptoms, sleep disturbances, anorexia, malnutrition, muscle wasting - cachexia, cachectic obesity, insulin resistance, dyslipidemia, alterations of steroid hormone axes, disturbances of the hypothalamic-pituitary-gonadal axis, elevated sympathetic tone, hypertension, volume expansion, decreased parasympathetic tone, inflammation-related anemia, bone loss, hypercoagulability, circadian rhythms of symptoms, and disease exacerbation by stress . The Origin of Chronic Inflammatory Systemic Diseases and Their Sequelae demonstrates concepts of neuroendocrine immunology, energy and water regulation, and evolutionary medicine in order to show that the uniform response that regulates systemic energy and water provision, has been positively selected for acute physiological responses and short-lived disease states, but is a misguided program in chronic inflammatory diseases and aging. Offers a broad conceptual framework with a strong clinical link, written in an easy to grasp style and demonstrating the link to aging research Describes the important principles derived from basic immunology that are used to explain pathogenesis of chronic inflammatory systemic diseases with a focus on autoimmunity Defines the bioenergetics and energy regulation of the body explaining common response pathways typical for systemic inflammation Makes use of evolutionary medicine theory to demonstrate the uniformity of the systemic response Explains the appearance of typical disease sequelae on the basis of the three pillars: neuroendocrine immunology, energy regulation, and evolutionary medicine theory Contains color figures and tables that explain the field to newcomers.
Inflammation --- Aging --- Inflammation. --- Immunological aspects. --- Diseases. --- Inflammatory process --- Pathology --- Anti-inflammatory agents --- Age --- Ageing --- Senescence --- Developmental biology --- Gerontology --- Longevity --- Age factors in disease --- Immunology of inflammation --- Immune response --- Physiological effect --- Immunology
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Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, long-term application of this program leads to typical disease sequelae such as fatigue / depressive symptoms, sleep disturbances, anorexia, malnutrition, muscle wasting - cachexia, cachectic obesity, insulin resistance, dyslipidemia, alterations of steroid hormone axes, disturbances of the hypothalamic-pituitary-gonadal axis, elevated sympathetic tone, hypertension, volume expansion, decreased parasympathetic tone, inflammation-related anemia, bone loss, hypercoagulability, circadian rhythms of symptoms, and disease exacerbation by stress . The Origin of Chronic Inflammatory Systemic Diseases and Their Sequelae demonstrates concepts of neuroendocrine immunology, energy and water regulation, and evolutionary medicine in order to show that the uniform response that regulates systemic energy and water provision, has been positively selected for acute physiological responses and short-lived disease states, but is a misguided program in chronic inflammatory diseases and aging.
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Neue Produkte und neue Märkte sind für Unternehmen wichtige Wachstumsfaktoren. Doch die meisten Innovationen erweisen sich als Flops und scheitern bereits bei der Einführung. „Von der Produktidee zum Markterfolg“ liefert eine systematische Gebrauchsanweisung, mit der die gezielte Suche nach neuen Produktideen, deren Entwicklung und Markteinführung gelingt. Rainer H. G. Großklaus beschreibt Schritt für Schritt, wie Sie klug Chancen im Markt aufspüren, systematisch Ideen finden, die Akzeptanz Ihres Produkts im Vorfeld testen, marktfähige Preise kalkulieren, einen detaillierten Marketingplan erarbeiten und Innovationen im Unternehmen erfolgreich managen. Checklisten und konkrete Beispiele aus B-to-C- und B-to-B-Unternehmen lassen sich direkt auf die eigene Praxis übertragen. Außerdem: Der Beitrag "Neue Produkte für ältere Zielgruppen" von Prof. Dr. Thomas Jendrosch erklärt, wie Sie erfolgreich Innovationen für die immer größer werdende Generation 50plus einführen. Der Inhalt Die Innovationsidee und der Innovationsprozess.- Externe und interne Analyse.- Techniken zur Ideengenerierung, -bewertung und -auswertung.- Testphase, Preiskalkulation und Markteinführungsplan. Die Zielgruppe Geschäftsführer in Unternehmen, Produktmanager, Marketingleiter und Mitarbeiter in Agenturen, die ihre Produktideen zum Erfolg führen wollen. Der Autor Rainer H.G. Großklaus war mehrere Jahre bei internationalen Markenartiklern und als Supervisor in einer großen Werbeagentur tätig, bevor er sich als Marketingberater selbstständig machte.
Leadership. --- Marketing. --- Business Strategy/Leadership.
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