Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Flow cytometric analysis of molecular, biochemical, genetic and developmental parameters using cellular fluorescence techniques as well as fluorescence-activated (FACS) or magnetic (MACS) cell sorting technologies provide unique options for molecular and cellular biology. In recent years, these technologies have been considerably advanced. 

In this second edition, all chapters have been updated according to the recent improvements and modifications. Further, new protocols have been added, such as on magnetic selection, magnetofluorescent liposomes, the cytometry of secreted products and microbead assays, as well as reporter gene assays for cytometry and cell selection. The recent technical developments allow diagnostic differentiation of cells according to specific gene expression, identification of rare disease-associated cells and isolation of well-defined cells at high purity for cell therapies. In basic research, analysis and isolation of cells according to the correlated expression of up to 10 gene products, expressed within, on or around the cell have become possible.

DIF (directe immunofluorescentie) --- Histology. Cytology --- DNA (deoxyribonucleic acid) --- flowcytometrie --- immunologie --- Immunology. Immunopathology --- Flow cytometry. --- Flow cytometry --- moleculaire biologie --- IMMUNOFLUORESCENCE --- CELL SORTING --- Deoxypentose Nucleic Acid DNA --- Monograph --- Immunofluorescence. --- Cell counting, Laser --- Cell separation, Laser --- Cell sorting, Laser --- Flow cytofluorometry --- Flow cytophotometry --- Laser cell counting --- Laser cell separation --- Laser cell sorting --- Cytometry --- Fluorescence --- Immunocytochemistry --- Immunoglobulins --- Immunology --- Technique

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with update.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

From 22 to 24 October 2006, internationally renowned scientists from the European Union and the United States met in Potsdam near Berlin, Germany, to discuss the future of chronic in?ammatory disease tre- ment.Thetitleofthesymposium,organizedbytheErnstScheringFo- dation,wasImmunotherapyin2020 VisionsandTrendsforTargeting In?ammatory Diseases . The presentations covered the main mechanisms of immunoregu- tion such as peripheral and central tolerance, epigenetic programming, immunologic memory, and regulatory networks in in?ammation as well as novel experimental and clinical approaches for targeting in?am- tion in autoimmunity and transplantation. Group discussions focused on the question of how recent ?ndings in immunological research can lead to improved diagnostics, new drugs, and better therapies. In this regard, beside novel approaches, the individualization of immunomodulatory therapies and the establishment of reliable biomarkers for assessing the speci?c immune situation along with patient response to therapies were discussed. In this volume, the symposium speakers give their view on current topics of immunopathophysiology and immunotherapy. The chapter by Prof. Rikard Holmdahl (Section for In?ammation Research, Lund University, Sweden) deals with the genetic basis of VI Preface in?ammatory diseases by means of gene polymorphisms and its - plications for the ?nding of new therapies. He describes how, based on the proven genetic component of rheumatoid arthritis demonstrated by clinical studies, a search for susceptibility genes in mice m- els was performed, which led to the de?nition of novel pathways - volvedintheimmunopathology ofarthritis.Concludingfromthis,novel therapeutic approaches are proposed which are experimentally proven yet.

Immunology. Immunopathology --- Pathology of the organs of movement --- immunologie --- reumatologie