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Platelet function, or clot formation, is difficult to assess, but extremely important because inadvertent or excessive platelet activation underlies many common cardiovascular disorders, such as myocardial infarction, unstable angina, and stroke. In Platelet Function: Assessment, Diagnosis, and Treatment, a panel of leading researchers and clinicians review the latest findings on the complexities of platelet function and the various means of inhibiting platelet clot formation. The authors delineate an up-to-date picture of platelet biology and describe methods for assessing platelet function, including the commonly used platelet aggregation, thromboxane production, procoagulant function, platelet function under flow, and the expression of platelet activation markers. The focus is both on the technology and the outcome of research on platelets, including the fast developing fields of proteomics and genomics and their application to platelet research. The clinical applications of the various methods for the assessment of platelet function in vivo, as well as antiplatelet therapy, are fully discussed. Comprehensive and state of the art, Platelet Function: Assessment, Diagnosis, and Treatment offers vascular researchers and clinicians a sound foundation for understanding platelet biology, assessing thrombotic risk in patients, and determining the rational dosing of antiplatelet agents.
Blood platelet disorders --- Blood platelets --- Diagnosis. --- Examination. --- Thrombocytopathy --- Blood --- Diseases --- Cardiology. --- Heart --- Internal medicine
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"The Routledge Handbook of Accounting Information Systems is a prestige reference work offering a comprehensive overview of the state of current knowledge and emerging scholarship in the discipline of AIS. The pace of technological driven change is rapid, and this revised edition provides a deeper focus on the technical underpinnings and organisational consequences of accounting information systems. It has been updated to capture the changes in technology since the previous edition. It now includes chapters and scholarly thought on artificial intelligence, predictive analytics and data visualisation, among others. Contributions from an international cast of authors provide a balanced overview of established and developing themes, identifying issues and discussing relevant debates. The chapters are analytical and engaging. Many chapters include cases or examples, and some provide additional resources for readers. The chapters also provide a reflection on where the research agenda is likely to advance in the future. This is a complete and indispensable guide for students and researchers in accounting and accounting information systems, academics and students seeking convenient access to an unfamiliar area, as well as established researchers seeking a single repository on the current debates and literature in the field"--
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Consumption of alcohol is a globally ubiquitous, often controversial activity, and business organizations in this sector are of significant social and economic relevance. This book draws on accounting records from the sector to reveal fresh and unique insights into the historic development of the production of alcoholic beverages.Offering a historic overview of the three major areas of the alcohol industry – brewing, distilling and wine – this book reveals the commonalities and differences which are present in the industry, while also highlighting its social impact. The editors bring together contributions from around the world, including Mexico, France, Japan and Ireland, to demonstrate how accounting has developed over time. Offering diverse geographical and historical perspectives, it explores multiple aspects of accounting within the industry, including internal control, earnings management, competition, and regulatory aspects. The fascinating insights into breweries, wineries, spirit distillers, vineyards and other related organizations provides a unique historic perspective of accounting systems, techniques and practices.Drawing on an international range of examples and rich archival material, this valuable research collection will be of great interest to researchers and advanced students of accounting and business history.
Alcoholic beverage industry --- Brewing industry --- Wine industry --- Accounting.
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Platelet function, or clot formation, is difficult to assess, but extremely important because inadvertent or excessive platelet activation underlies many common cardiovascular disorders, such as myocardial infarction, unstable angina, and stroke. In Platelet Function: Assessment, Diagnosis, and Treatment, a panel of leading researchers and clinicians review the latest findings on the complexities of platelet function and the various means of inhibiting platelet clot formation. The authors delineate an up-to-date picture of platelet biology and describe methods for assessing platelet function, including the commonly used platelet aggregation, thromboxane production, procoagulant function, platelet function under flow, and the expression of platelet activation markers. The focus is both on the technology and the outcome of research on platelets, including the fast developing fields of proteomics and genomics and their application to platelet research. The clinical applications of the various methods for the assessment of platelet function in vivo, as well as antiplatelet therapy, are fully discussed. Comprehensive and state of the art, Platelet Function: Assessment, Diagnosis, and Treatment offers vascular researchers and clinicians a sound foundation for understanding platelet biology, assessing thrombotic risk in patients, and determining the rational dosing of antiplatelet agents.
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