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Prion Diseases --- Prions --- Prions. --- Prions (virologie). --- Infections à prions --- genetics. --- Genetics.

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Medical microbiology, virology, parasitology --- Neuropathology --- Infectious diseases. Communicable diseases

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"Infectious proteins called prions are responsible for the devastating transmissible spongioform encephalopathy Creutzfeldt-Jakob disease. Prions are misfolded versions of proteins that replicate by converting their normal cellular counterparts into new prions and may play an important role in numerous other conditions, including Alzheimer and Parkinson's disease. Highlights include: Structural biology of PrP prions - Genetics of APP in Alzheimer's disease - Challenges of therapeutics for prion diseases and blood-brain barrier "--

Prions --- Prion diseases

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"Prions are infectious proteins responsible for diseases such as Creutzfeldt-Jakob disease and "mad cow" disease. They are misfolded versions of normal proteins that replicate by converting their normal cellular counterparts into abnormal prion proteins that disrupt cell function and can be transmitted to other cells and individuals. This book examines our under-standing of their structure, biochemistry, and pathophysiology. Highlights include: - Experimental approaches to neurodegeneration - Prions, Chaperones, and Proteostasis in Yeast - The Aggregation and Prion-like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion-like Disease? - Neuropathology of NDs"-- "Prions are infectious proteins responsible for diseases such as Creutzfeldt-Jakob disease and "mad cow" disease. They are misfolded versions of normal proteins that replicate by converting their normal cellular counterparts into abnormal prion proteins that disrupt cell function and can be transmitted to other cells and individuals. This book examines our under-standing of their structure, biochemistry, and pathophysiology"--

Prions. --- Prion diseases. --- Nervous System Diseases. --- Infections à prions. --- Prions (virologie)

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