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This volume is a concise yet comprehensive resource for physicians dealing with, and interested in, the field of molecular pathology in dermatopathology. The book includes descriptions of the techniques and their application to cutaneous diseases and describes possible future techniques and their use in dermatopathology. Special emphasis is also given to the practical application of these techniques to particular situations illustrated by demonstrative cases. Written by experts in their fields, Precision Molecular Pathology of Dermatologic Diseases is of great value to pathologists, dermatologists, resident and fellows, internists, and general practitioners who deal with dermatologic diseases.

Medicine & Public Health. --- Pathology. --- Dermatology. --- Molecular Medicine. --- Medicine. --- Médecine --- Dermatologie --- Pathologie --- Skin -- Diseases. --- Skin -- Histopathology. --- Skin --- Pathology --- Skin Diseases --- Pathology, Molecular --- Methods --- Molecular Diagnostic Techniques --- Molecular Biology --- Clinical Laboratory Techniques --- Investigative Techniques --- Skin and Connective Tissue Diseases --- Medicine --- Biochemistry --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Occupations --- Diseases --- Disciplines and Occupations --- Biological Science Disciplines --- Natural Science Disciplines --- Health & Biological Sciences --- Molecular aspects --- Histopathology --- Diseases. --- Histopathology. --- Cutaneous diseases --- Dermatoses --- Molecular biology. --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Molecular biochemistry --- Molecular biophysics --- Biophysics --- Biomolecules --- Systems biology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Physicians --- Dermatology --- Health Workforce

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This book provides a comprehensive, state-of-the-art account of the role of immunohistochemistry in the diagnosis of skin tumors, which is crucial given that overlapping histologic features and unusual morphologic changes can lead to considerable diagnostic uncertainty. The book reviews in detail the sensitivity and specificity of commonly available antibodies and their pattern of immunostaining. Readers will learn when to order antibodies and how to interpret findings. In addition, prognostic markers are evaluated and emphasis placed on the pitfalls commonly encountered when evaluating these neoplasms. The informative text is complemented by a wealth of superb images. Helpful histograms and algorithms are included, and clear guidance is provided on the application and interpretation of less commonly used antibodies and immunostains. With the emergence of many immunomarkers, immunohistochemistry has become a vital ancillary diagnostic tool in dermatopathology and an essential adjunct for the correct identification of skin neoplasms. Indeed, immunohistochemistry has replaced simple morphologic evaluation as the definitive diagnostic method for various tumor types. The complexity of some skin neoplasms makes it imperative that the role of immunohistochemistry in subtyping these conditions is clearly understood. Against this background, Applied Immunohistochemistry in the Evaluation of Skin Neoplasms will serve as an extremely valuable resource for practicing dermatopathologists and pathologists.

Medicine. --- Laboratory medicine. --- Dermatology. --- Pathology. --- Medicine & Public Health. --- Laboratory Medicine. --- Skin --- Immunohistochemistry. --- Tumors --- Diagnosis. --- Immunohistology --- Cutis --- Integument (Skin) --- Beauty, Personal --- Body covering (Anatomy) --- Histochemistry --- Immunochemistry --- Medical laboratories. --- Diagnosis, Laboratory --- Health facilities --- Laboratories --- Medicine --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Clinical medicine --- Clinical pathology --- Diagnostic laboratory tests --- Laboratory diagnosis --- Laboratory medicine --- Medical laboratory diagnosis --- Diagnosis --- Pathology

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The Demos Surgical Pathology Guides series presents in summary and visual form thebasic knowledge base that every practicing pathologist needs every working day. Seriesvolumes cover the major specialty areas of surgical pathology, and coverage emphasizesthe key entities and diagnoses that pathologists will see in practice, and that they mustknow whether in training or practice. The emphasis is on the basic morphology with newertechniques represented where they are frequently used. The series provides a handy summaryand quick reference that any pathology resident or fellow will find useful. Exp

Skin --- Cutaneous diseases --- Dermatoses --- Dermatology --- Dermatitis --- Inflammation --- Inflammation. --- Diseases. --- Diseases

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This book offers a practical approach to the histologic analysis of a wide range of melanocytic skin lesions, including various nevi and different forms of melanoma, as well as pigmented non-melanocytic lesions. In addition, sentinel node biopsy findings and the use of special ancillary studies are covered in detail. Each chapter presents illustrative cases that document the route to correct diagnosis. An important feature of the book is the clinical-pathologic correlation of challenging melanocytic tumors; accordingly, it will appeal not only to pathologists (general surgical pathologists and dermatopathologists) but also to dermatologists (including dermatopathologists). The book contains some 250 color photos as well as tables and algorithms designed to assist in the diagnosis of difficult cases.

Oncology. Neoplasms --- Pathological dermatology --- Pathology --- tumoren --- pathologie --- dermatologie --- oncologie

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Pathology of Challenging Melanocytic Neoplasms offers a dynamic text where readers will encounter a broad spectrum of challenging melanocytic lesions, both benign and malignant, and acquire a solid, working knowledge that they can immediately apply to daily diagnosis. The volume emphasizes the practical application of basic morphologic principles, immunohistochemistry, and ancillary methods in order to secure a confident diagnosis. Rather than being yet another encyclopedic work of reference, this volume takes a fresh approach as it resembles a series of stimulating seminars employing exemplary case material to highlight, illustrate, and succinctly discuss the key points. To this end, the reader is presented first with a section of introductory chapters and is then guided through a series of cases that pose a significant diagnostic challenge. By comprehensively comparing and contrasting two or more related entities, each such chapter illuminates an intellectual pathway through which an important diagnostic puzzle can be solved. To broaden the differential diagnosis even further, additional illustrative cases are added to each discussion. Tables also summarize key points. Written by experts in the field, Pathology of Challenging Melanocytic Neoplasms is of great value to surgical pathologists in practice and dermatologists as well as residents and fellows training in these specialties.

Molecular biology --- Pathological dermatology --- Pathology --- pathologie --- dermatologie --- moleculaire biologie