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Sphingolipids are lipid components of the plasma membrane of eukaryotic cells with an important function in signaling mechanisms in the cell. This book provides insight into the physiological and pathophysiological role of sphingolipids and in particular its derivative ceramide. The function of Sphingolipids in cell signaling with regard to infectious and lung diseases, cancer, cardiovascular diseases and neuropsychiatric disorders are described and treated in distinct parts. Together with Volume 215 from the same Editors, the collection represents a unique, comprehensive work on Sphingolipids, providing information on both: Sphingolipid basic biology as well as its important function in a (patho)physiological context. The book is written for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians in pharmacology, oncology, cardiology, neurology and infectious disease. .
Sphingolipids. --- Sphingolipids --- Cellular signal transduction. --- Pathophysiology. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Lipids --- Sphingosine --- Toxicology. --- Cardiology. --- Oncology. --- Immunology. --- Neurosciences. --- Lipids. --- Pharmacology/Toxicology. --- Cancer Research. --- Lipidology. --- Lipides --- Lipins --- Lipoids --- Biomolecules --- Steroids --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Immunobiology --- Life sciences --- Serology --- Tumors --- Heart --- Internal medicine --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Diseases --- Toxicology --- Pharmacology. --- Cancer research. --- Cancer research --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect
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Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of important enzymes, sphingolipid metabolism and synthesis. The second part of this first volume focuses on drug development and pharmacology. The book is intended for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians working in pharmacology, oncology, cardiology, neurology and infectious disease. Together with Volume 216 by the same editors, the collection represents a unique, comprehensive work on sphingolipids, providing information on both sphingolipids’ basic biology (including synthesis, metabolism and cell biology) and their important function in a (patho-)physiological context.
Cell adhesion molecules. --- Cellular signal transduction. --- Sphingolipids -- Physiological effect. --- Sphingolipids. --- Sphingolipids --- Lipids --- Metabolic Phenomena --- Membrane Lipids --- Phenomena and Processes --- Chemicals and Drugs --- Metabolism --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Lipids. --- Lipides --- Lipins --- Lipoids --- Medicine. --- Cancer research. --- Molecular biology. --- Pharmacology. --- Oncology. --- Cell biology. --- Cell membranes. --- Biomedicine. --- Pharmacology/Toxicology. --- Membrane Biology. --- Cancer Research. --- Molecular Medicine. --- Cell Biology. --- Biomolecules --- Steroids --- Sphingosine --- Toxicology. --- Cytology. --- Oncology . --- Tumors --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Cell surfaces --- Cytoplasmic membranes --- Plasma membranes --- Plasmalemma --- Membranes (Biology) --- Glycocalyces --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Health Workforce --- Cell membranes . --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Systems biology --- Cancer research --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect
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Sphingolipids --- Ceramides --- Physiological effect. --- Physiological effect.
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Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of important enzymes, sphingolipid metabolism and synthesis. The second part of this first volume focuses on drug development and pharmacology. The book is intended for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians working in pharmacology, oncology, cardiology, neurology and infectious disease. Together with Volume 216 by the same editors, the collection represents a unique, comprehensive work on sphingolipids, providing information on both sphingolipids’ basic biology (including synthesis, metabolism and cell biology) and their important function in a (patho-)physiological context.
Biomembranes --- Histology. Cytology --- Molecular biology --- Toxicology --- Pharmacology. Therapy --- Pathological biochemistry --- Human medicine --- celmembranen --- membranen (biologie) --- medische biochemie --- farmacologie --- biochemie --- biologie --- biomedische wetenschappen --- multimedia --- toxicologie --- cytologie --- histologie --- moleculaire biologie --- enzymen
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Sphingolipids are lipid components of the plasma membrane of eukaryotic cells with an important function in signaling mechanisms in the cell. This book provides insight into the physiological and pathophysiological role of sphingolipids and in particular its derivative ceramide. The function of Sphingolipids in cell signaling with regard to infectious and lung diseases, cancer, cardiovascular diseases and neuropsychiatric disorders are described and treated in distinct parts. Together with Volume 215 from the same Editors, the collection represents a unique, comprehensive work on Sphingolipids, providing information on both: Sphingolipid basic biology as well as its important function in a (patho)physiological context. The book is written for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians in pharmacology, oncology, cardiology, neurology and infectious disease. .
Immunology. Immunopathology --- Toxicology --- Pharmacology. Therapy --- Oncology. Neoplasms --- Semiology. Diagnosis. Symptomatology --- Pathological biochemistry --- Pathology of the circulatory system --- Neuropathology --- Human medicine --- immunologie --- lipiden --- medische biochemie --- neurologie --- farmacologie --- biochemie --- biomedische wetenschappen --- multimedia --- toxicologie --- cholesterol --- oncologie --- cardiologie --- besmettelijke ziekten
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