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The microbiological burden on an aging host is enormous, and clinically significant. As humans are living longer there is a greater propensity to infection. This risk is substantially heightened in elderly individuals who are predisposed to infection. Do the microbiological changes that occur within and upon the host influence the process of ageing or is it the biological changes of the host that affects the host’s microbiology? Do such changes therefore affect the host’s propensity to disease? Are there ways of enhancing life expectancy by reducing certain bacteria from proliferating or conversely by enhancing the survival of beneficial bacteria? Microbiology & Aging: Clinical Manifestations encompasses a collection of reviews that highlight the significance of, and the crucial role, that microorganisms play in the human life cycle and considers the microbiology of the host in different regions of the body during the aging process.

Aging. --- Aging --- Molecular microbiology --- Disease Susceptibility --- Age Factors --- Infection --- Aged --- Physiology --- Disease Attributes --- Growth and Development --- Epidemiologic Factors --- Biological Science Disciplines --- Adult --- Body Constitution --- Bacterial Infections and Mycoses --- Age Groups --- Public Health --- Physiological Phenomena --- Diseases --- Quality of Health Care --- Physiological Processes --- Pathologic Processes --- Natural Science Disciplines --- Health Care Quality, Access, and Evaluation --- Pathological Conditions, Signs and Symptoms --- Disciplines and Occupations --- Environment and Public Health --- Persons --- Phenomena and Processes --- Health Care --- Named Groups --- Microbiology & Immunology --- Human Anatomy & Physiology --- Biology --- Health & Biological Sciences --- Molecular aspects --- Molecular microbiology. --- Molecular aspects. --- Microorganisms --- Molecular bacteriology --- Molecular aging --- Medicine. --- Medical microbiology. --- Biomedicine. --- Medical Microbiology. --- Microbiology --- Molecular biology --- Microbiology. --- Microbial biology

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Biofilms in Infection and Disease Control: A Healthcare Handbook outlines the scientific evidence and rationale for the prevention of infection, the role biofilms play in infection control, and the issues concerning their resistance to antimicrobials. This book provides practical guidance for healthcare and infection control professionals, as well as students, for preventing and controlling infection. Biofilms are the most common mode of bacterial growth in nature. Highly resistant to antibiotics and antimicrobials, biofilms are the source of more than 65 percent of health care associated infections (HCAI), which, according to the WHO, affect 1.4 million people annually. Biofilms are involved in 80 percent of all microbial infections in the body, including those associated with medical devices such as catheters, endotracheal tubes, joint prostheses, and heart valves. Biofilms are also the principle causes of infections of the middle-ear, dental caries, gingivitis, prostatitis and cystic fibrosis. Importantly, biofilms also significantly delay wound healing and reduce antimicrobial efficiency in at-risk or infected skin wounds.

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Wounds and injuries --- Wound Infection --- Biofilms. --- Chronic Disease. --- Wound Healing --- Infections --- Microbiology --- microbiology. --- prevention & control. --- physiology.

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Biofilms are implicated in many common medical problems including urinary tract infections, catheter infections, middle-ear infections, dental plaque, gingivitis, and some less common but more lethal processes such as endocarditis and infections in cystic fibrosis.  However, the true importance of biofilms in the overall process of disease pathogenesis has only recently been recognized. Bacterial biofilms are one of the fundamental reasons for incipient wound healing failure in that they may impair natural cutaneous wound healing and reduce topical antimicrobial efficiency in infected skin wounds.  Their existence explains many of the enigmas of microbial infection and a better grasp of the process may well serve to establish a different approach to infection control and management.   Biofilms and their associated complications have been found to be involved in up to 80% of all infections.  A large number of studies targeted at the bacterial biofilms have been conducted, and many of them are referred to in this book, which is the first of its kind.   These clinical observations emphasize the importance of biofilm formation to both superficial and systemic infections, and the inability of current antimicrobial therapies to ‘cure’ the resulting diseases even when the in vitro tests suggest that they should be fully effective. In veterinary medicine the concept of biofilms and their role in the pathogenesis of disease has lagged seriously behind that in human medicine.  This is all the more extraordinary when one considers that much of the research has been carried out using veterinary species in experimental situations.   The clinical features of biofilms in human medicine is certainly mimicked in the veterinary species but there is an inherent and highly regrettable indifference to the failure of antimicrobial therapy in many veterinary disease situations, and this is probably at its most retrograde in veterinary wound management.  Biofilms and Veterinary Medicine is specifically focused on discussing the concerns of biofilms to health and disease in animals and provides a definitive text for veterinary practitioners, medical and veterinary students, and researchers.

Veterinary bacteriology --- Bacterial diseases in animals --- Biofilms --- Veterinary medicine --- Veterinary therapeutics --- Biology --- Health & Biological Sciences --- Veterinary Medicine --- Microbiology & Immunology --- Biofilms. --- Veterinary medicine. --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Life sciences. --- Microbiology. --- Bacteriology. --- Life Sciences. --- Veterinary Medicine. --- Medicine --- Animal health --- Animals --- Domestic animals --- Livestock --- Diseases --- Losses --- Microbial aggregation --- Microbial ecology --- Veterinary Medicine/Veterinary Science. --- Microbial biology --- Microorganisms --- Microbiology

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This comprehensive text describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. It also details the methods for detecting and identifying waterborne microorganisms, the ways in which they are removed from water, and the risks they present to water users. This handbook will serve as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students.