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Veterans who have served in the military since September 11, 2001, are at particularly high risk for co-occurring substance use disorders (SUDs) and mental health disorders, such as posttraumatic stress disorder and depression. Many treatment facilities require abstinence from substances prior to admission for mental health care, but the combination of symptoms that these disorders present makes them difficult to treat separately. Thus, integrated care—in which both SUDs and mental health problems are addressed concurrently—is a recommended form of treatment for these veterans. To help improve access to effective treatment for these veterans, the authors review the literature on efficacious approaches to treating SUDs alone and alongside mental health disorders. They also present findings from an analysis of the availability of treatment centers that offer SUD care for veterans and from a series of interviews and site visits with treatment providers. The authors conclude with guidance and recommendations to support the delivery of quality care for veterans with SUDs and, ultimately, to help expand and enhance treatment opportunities for veterans with co-occurring SUDs and mental health disorders.