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Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease.The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins

Cancer -- Diagnosis. --- Cancer -- Therapy. --- Cancer -- Treatment. --- Neoplasms -- Therapy. --- Cancer --- Tumors --- Biomedical materials --- Biomedical and Dental Materials --- Manufactured Materials --- Diseases --- Drug Therapy --- Chemicals and Drugs --- Specialty Uses of Chemicals --- Technology, Industry, and Agriculture --- Therapeutics --- Technology, Industry, Agriculture --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemical Actions and Uses --- Biocompatible Materials --- Nanostructures --- Drug Delivery Systems --- Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Treatment --- Diagnosis --- Prevention --- Treatment. --- Cancer therapy --- Cancer treatment --- Therapy --- Biomedical materials. --- Diagnosis. --- Prevention.

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Human biochemistry

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Hydrogels are networks of polymer chains which can produce a colloidal gel containing over 99 per cent water. The superabsorbency and permeability of naturally occurring and synthetic hydrogels give this class of materials an amazing array of uses. These uses range from wound dressings and skin grafts to oxygen-permeable contact lenses to biodegradable delivery systems for drugs or pesticides and scaffolds for tissue engineering and regenerative medicine. Biomedical Applications of Hydrogels Handbook provides a comprehensive description of this diverse class of materials, covering both synthesis and properties and a broad range of research and commercial applications. The Handbook is divided into four sections: Stimuli-Sensitive Hydrogels, Hydrogels for Drug Delivery, Hydrogels for Tissue Engineering, and Hydrogels with  Unique Properties. Key Features: Provides comprehensive coverage of the basic science and applications of a diverse class of materials Includes both naturally occurring and synthetic hydrogels Edited and written by worldwide leaders in the field Editorial Advisory Board: Nicholas A. Peppas, Chair (The University of Texas at Austin)   Allan Hoffman (University of Washington) Emo Chiellini (University of Pisa)   Fu-Zhai Cui (Tsinghua University)   Karel Dusek (Academy of Sciences of the Czech Republic)   Jindrich Kopecek (University of Utah)   Claudio Migliaresi (University of Trento)   Yoshihito Osada (Hokkaido University)   Buddy D. Ratner (University of Washington) Nathan Ravi (Washington University in St. Louis)   Etienne Schacht (Ghent University)   Tianwei Tan (Bejing University of Chemical Technology).

Biomedical materials. --- Colloids. --- Colloids in medicine --- Prostheses and Implants --- Biomedical and Dental Materials --- Gels --- Drug Therapy --- Culture Techniques --- Culture Media --- Natural Science Disciplines --- Investigative Techniques --- Hydrogels --- Drug Delivery Systems --- Tissue Scaffolds --- Biocompatible Materials --- Chemistry --- Methods --- Tissue Engineering --- Disciplines and Occupations --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Colloids --- Therapeutics --- Equipment and Supplies --- Manufactured Materials --- Specialty Uses of Chemicals --- Clinical Laboratory Techniques --- Chemicals and Drugs --- Technology, Industry, and Agriculture --- Complex Mixtures --- Chemical Actions and Uses --- Dosage Forms --- Technology, Industry, Agriculture --- Pharmaceutical Preparations --- Health & Biological Sciences --- Biomedical Engineering --- Nanomedicine. --- Dispersoids --- Sols --- Materials science. --- Biomaterials. --- Materials Science. --- Medicine --- Nanotechnology --- Amorphous substances --- Chemistry, Physical and theoretical --- Diffusion --- Matter --- Micelles --- Particles --- Rheology --- Solution (Chemistry) --- Surface chemistry --- Properties --- Biocompatible materials --- Biomaterials --- Medical materials --- Biomedical engineering --- Materials --- Biocompatibility --- Prosthesis --- Bioartificial materials --- Hemocompatible materials --- Biomaterials (Biomedical materials)

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This book was conceived from a simple question as to why cancer is so difficult to treat.  Ultimately we want to find ways to cure cancers, but that may be an elusive dream at least with the technologies we have now and expect to have in the near future.  This leads the question of whether it is possible to improve current cancer treatment methods, especially from the perspective of enhancing targeted drug delivery to tumors.  This volume is designed to provide information related to the difficulties in treating cancers through targeted drug delivery, our current understanding of cancer biology, and potential technologies that might be used to achieve enhanced drug delivery to tumors. An ideal drug delivery system for treating cancers would maximize the therapeutic efficacy with minimal side effects in clinical applications.  The seemingly improved anticancer efficacy of the current nanoparticle-based formulations needs to be viewed from the context of very poor success rates for translation to human applications.  The results of in vitro cell culture models and small animal in vivo experiments have not been extrapolated to clinical applications.  Finding the reasons for the lack of successful translation is required if we are to discover approaches to substantially extend the survival time of cancer patients, and hopefully identify cures. Cancer Targeted Drug Delivery: Elusive Dream describes some answers of achieving the so far elusive dream of treating cancers like other chronic diseases with therapies that focus using improved drug delivery systems designed to better align with the unique biological and physiological properties of cancer.

Cancer --- Antineoplastic agents --- Drug delivery systems --- Therapeutic Uses --- Therapeutics --- Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Pharmacologic Actions --- Chemical Actions and Uses --- Chemicals and Drugs --- Drug Therapy --- Antineoplastic Agents --- Drug Delivery Systems --- Neoplasms --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Chemotherapy --- Pharmaceutical technology. --- Toxicology. --- Chemicals --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Toxicology --- Medicine. --- Pharmacology. --- Biomedicine. --- Pharmaceutical Sciences/Technology. --- Pharmacology/Toxicology. --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Technology --- Drug effects --- Medical pharmacology --- Medical sciences --- Drugs --- Pharmacy --- Physiological effect