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 Among the many GPCRs discovered, the calcitonin family of receptors comprise of members that regulate a number of physiological processes and are involved in many pathological conditions. Therefore, understanding how these receptors function is a critical question in the field. When Foord and his colleagues discovered that a single transmembrane protein called Receptor Activity Modifying Proteins (RAMPs) could modulate the surface expression of GPCRs of the calcitonin family, it widely opened the field of receptor life cycle. Hundreds of studies have confirmed the importance of RAMPs in the life cycle of this receptor family. Receptor biology is a rapidly expanding field and with the advances in cell and molecular biology and in vivo techniques, it is very likely that the field of RAMPs will explode further and many unanswered questions will be answered with in the next few years.

Cell receptors. --- Cellular signal transduction. --- G proteins -- Receptors. --- Adaptor Proteins, Signal Transducing --- Membrane Proteins --- Proteins --- Intracellular Signaling Peptides and Proteins --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Receptor Activity-Modifying Proteins --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- G proteins --- G proteins. --- Receptors. --- GTP-binding proteins --- GTP regulatory proteins --- Guanine nucleotide-binding proteins --- Guanine nucleotide regulatory proteins --- Medicine. --- Molecular biology. --- Cell biology. --- Biomedicine. --- Biomedicine general. --- Cell Biology. --- Molecular Medicine. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Membrane proteins --- Cytology. --- Health Workforce --- Biomedicine, general.

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Histology. Cytology --- Molecular biology --- Human biochemistry --- medische biochemie --- biochemie --- cytologie --- histologie --- moleculaire biologie

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Histology. Cytology --- Molecular biology --- Human biochemistry --- medische biochemie --- biochemie --- cytologie --- histologie --- moleculaire biologie