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The somatotropic axis is one of the major hormonal systems regulating postnatal growth in mammals. It interacts with the central nervous system on several levels. Growth hormone (GH) and insulin-like growth factor-I (IGF-I) receptors are expressed in many brain areas including the hippocampus, pituitary and hypothalamus. GH and IGF-I are important factors in the development and differentiation of the CNS and have protective properties in dementia, as well as in traumatic and ischaemic injury of the CNS. Also GH has an important impact on mood and well-being with GH secretory capacity being red

Growth hormone releasing factor. --- Neuroendocrinology. --- Somatotropin. --- Growth hormone --- Pituitary growth hormone --- Somatotrophic hormone --- Somatotrophin --- Somatotropic hormone --- Somatropin --- Pituitary hormones --- Endocrinology --- Neurology --- Neurohormones --- GH-RH (Hormone) --- GHRH (Hormone) --- GRF (Hormone) --- Growth hormone releasing hormone --- Somatoliberin --- Somatotropin releasing factor --- Somatotropin releasing hormone --- Pituitary hormone releasing factors