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This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid to the exciting developments in the fields of proton irradiation and frameless image-guided ablative radiotherapy. The book documents fully how refined combined modality approaches and significant technical advances in radiation treatment planning and delivery have facilitated the re-irradiation of previously exposed volumes, allowing both palliative and curative approaches to be pursued at various disease sites. Professionals involved in radiation treatment planning and multimodal oncology treatment will find it to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.

Medicine. --- Radiotherapy. --- Oncology. --- Medicine & Public Health. --- Combined modality therapy. --- Combined modality treatment --- Multi-modal therapy --- Multimodal therapy --- Multimodal treatment --- Radiation therapy --- Therapeutics --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Radiological services --- Oncology  . --- Tumors

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A look at the recent oncology literature or a search of one of the common databases reveals a steadily increasing number of nomograms and other prognostic models, some of which are also available in the form of web-based tools. These models may predict the risk of relapse, lymphatic spread of a given malignancy, toxicity, survival, etc. Pathology information, gene signatures, and clinical data may all be used to compute the models. This trend reflects increasingly individualized treatment concepts and also the need for approaches that achieve a favorable balance between effectiveness and side-effects. Moreover, optimal resource utilization requires prognostic knowledge, for example to avoid lengthy and aggressive treatment courses in patients with a short survival expectation. In order to avoid misuse, it is important to understand the limits and caveats of prognostic and predictive models. This book provides a comprehensive overview of such decision tools for radiation oncology, stratified by disease site, which will enable readers to make informed choices in daily clinical practice and to critically follow the future development of new tools in the field.

Cancer --- Oncology. --- Radiotherapy. --- Tumors --- Treatment --- Oncology  . --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Radiological services

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New developments such as refined combined modality approaches and significant technical advances in radiation treatment planning and delivery are facilitating the re-irradiation of previously exposed volumes. As a consequence, both palliative and curative approaches can be pursued at various disease sites. Re-irradiation: New Frontiers is the first book to provide a comprehensive overview on current re-irradiation strategies. Re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance are all discussed in detail. In addition, disease-specific chapters document recent clinical results and future research directions. Professionals involved in radiation treatment planning and multimodal oncology treatment will find this book to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.

Cancer -- Treatment. --- Electronic books. -- local. --- Irradiation -- Research. --- Irradiation. --- Neoplastic Processes --- Therapeutics --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Neoplasms --- Pathologic Processes --- Pathological Conditions, Signs and Symptoms --- Diseases --- Combined Modality Therapy --- Neoplasm Recurrence, Local --- Radiotherapy --- Medicine --- Health & Biological Sciences --- Radiology, MRI, Ultrasonography & Medical Physics --- Oncology --- Cancer --- Irradiation --- Treatment. --- Research. --- Cancer therapy --- Cancer treatment --- Therapy --- Medicine. --- Radiology. --- Radiotherapy. --- Oncology. --- Medicine & Public Health. --- Imaging / Radiology. --- Radiation --- Radiology, Medical. --- Oncology  . --- Tumors --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Radiological services --- Radiological physics --- Physics

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A look at the recent oncology literature or a search of one of the common databases reveals a steadily increasing number of nomograms and other prognostic models, some of which are also available in the form of web-based tools. These models may predict the risk of relapse, lymphatic spread of a given malignancy, toxicity, survival, etc. Pathology information, gene signatures, and clinical data may all be used to compute the models. This trend reflects increasingly individualized treatment concepts and also the need for approaches that achieve a favorable balance between effectiveness and side-effects. Moreover, optimal resource utilization requires prognostic knowledge, for example to avoid lengthy and aggressive treatment courses in patients with a short survival expectation. In order to avoid misuse, it is important to understand the limits and caveats of prognostic and predictive models. This book provides a comprehensive overview of such decision tools for radiation oncology, stratified by disease site, which will enable readers to make informed choices in daily clinical practice and to critically follow the future development of new tools in the field.

Radiotherapy. Isotope therapy --- Oncology. Neoplasms --- Physical methods for diagnosis --- farmacologie --- pneumologie --- radiotherapie --- oncologie --- gentherapie --- radiologie --- medische beeldvorming

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New developments such as refined combined modality approaches and significant technical advances in radiation treatment planning and delivery are facilitating the re-irradiation of previously exposed volumes. As a consequence, both palliative and curative approaches can be pursued at various disease sites. Re-irradiation: New Frontiers is the first book to provide a comprehensive overview on current re-irradiation strategies. Re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance are all discussed in detail. In addition, disease-specific chapters document recent clinical results and future research directions. Professionals involved in radiation treatment planning and multimodal oncology treatment will find this book to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.

Radiotherapy. Isotope therapy --- Oncology. Neoplasms --- Physical methods for diagnosis --- farmacologie --- radiotherapie --- oncologie --- radiologie --- medische beeldvorming