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Systematic Evidence Reviews to Answer Health Care Questions provides accessible, concise information about the state-of-the-art methods of systematic review, from key question formulation and selecting evidence to assessing the quality of included studies and reporting results. Key topics are organized around essential steps in conducting reviews as well as important issues or dilemmas encountered during the process. Although the state-of-the-art methods serve as core material, the book also presents different approaches that are sometimes needed when basic rules do not apply. Its perspective is practical and patient-centered. The book incorporates information from sources representing standards in the field, as well as from teaching and training materials developed at the Oregon Evidence-based Practice Center. Examples from existing projects are used to illustrate specific issues throughout the book. Medical practice guidelines, health care policies, and insurance coverage decisions are increasingly informed by evidence from clinical trials and other research of the benefits, harms, and comparisons of treatments, tests, and procedures. Systematic reviews provide a scientific approach to collecting and synthesizing biomedical information to answer questions that are essential to developing these guidelines and policies. However, standards for conducting systematic reviews have been lacking, and translation of evidence to practice has often been derailed when researchers hand off their systematic reviews to users who are unfamiliar with how to effectively use them. Several types of systematic reviews have evolved depending on the scope and goals of the review, such as technology assessments, comparative effectiveness reviews, and state-of-the-science reviews, for example. Although the different types of systematic reviews have much in common, they also vary in important ways. Each review requires methods appropriate to the specific clinical and health care questions it addresses, its scope, and the existing body of research. For example, a comparative effectiveness review of two or more medications previously studied in several high-quality randomized controlled trials would most likely use methods of statistical meta-analysis to pool trials to compare medications. In contrast, a state-of-the-science review to determine if specific symptoms are related to a health condition would qualitatively synthesize results of observational studies. As with all research, investigators are confronted with many decisions during the course of conducting a systematic evidence review. While investigators need to embrace the standards and accepted methodology of the discipline, they must also approach each question as unique in order to achieve meaningful results.

Biology --- Medicine --- Health Workforce --- Biological research --- Biomedical research --- Research. --- Biomedical Research --- Review Literature as Topic --- Medical care --- Systematic reviews (Medical research)

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Breast --- Cancer --- Treatment.

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Outside back cover : "Written by renowned epidemiologists and public health experts, this unique text provides complete, concise coverage of epidemiology, biostatistics, preventive medicine, and public health in clear, easy-to-understand terms. One convenient volume delivers must-know content in four complex areas-information that's sure to be covered in today's classrooms and on USMLE exams-presented with a clinical focus and real-life medical examples throughout. Depth of coverage, concise writing style, outstanding online review questions, a clinical emphasis . these features and more make Jekel's your go-to resource for learning, study, and review. Focuses on clinical problem solving and decision making using epidemiologic concepts and examples. Contains more clinical cases throughout, including global examples. Offers expanded coverage of the impact of big data and precision medicine, as well as an updated and reorganized biostatistics section. Features quick-reference boxes that showcase key concepts and calculations, and dynamic illustrations that facilitate learning using a highly visual approach. Provides almost 300 multiple-choice chapter review questions and answers in print, with additional questions and more online at Student Consult. Aligns content to board blueprints for the USMLE as well as the three specialties certified by the American Board of Preventive Medicine: Occupational Medicine, and Public Health & General Preventive Medicine-and is recommended by the ABPM as a top review source for its core specialty examination."

Epidemiology --- Biometry --- Preventive Health Services --- Public Health --- organization & administration --- Epidemiologic Methods --- Preventive Medicine --- Biométrie --- Épidémiologie --- Médecine préventive --- Méthodes épidémiologiques --- Santé publique --- Community Health --- Environment, Preventive Medicine & Public Health --- Environment, Preventive Medicine and Public Health --- Health, Community --- Health, Public --- Education, Public Health Professional --- Medicine, Preventive --- Preventative Care --- Preventative Medicine --- Preventive Care --- Care, Preventative --- Care, Preventive --- Medicine, Preventative --- Disease --- Primary Prevention --- Anthropology, Physical --- Statistics as Topic --- Epidemiologic Method --- Epidemiological Methods --- Methods, Epidemiologic --- Epidemiological Method --- Method, Epidemiologic --- Method, Epidemiological --- Methods, Epidemiological --- prevention & control --- methods --- Preventive Health Services - organization & administration --- Epidemiologic Methods. --- Epidemiology. --- Biometry. --- Preventive Medicine. --- Public Health. --- Preventive Health Services. --- Biométrie. --- Épidémiologie. --- Médecine préventive. --- Méthodes épidémiologiques. --- Santé publique.

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Suicide --- Prevention.

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Menopause --- Evidence-based medicine --- Clinical Medicine --- Epidemiologic Studies --- Investigative Techniques --- Evidence-Based Practice --- Pathological Conditions, Signs and Symptoms --- Hormone Replacement Therapy --- Climacteric --- Sexual Development --- Health Occupations --- Medicine --- Drug Therapy --- Diseases --- Reproductive Physiological Phenomena --- Health Care Evaluation Mechanisms --- Epidemiologic Methods --- Therapeutics --- Reproductive Physiological Processes --- Reproductive and Urinary Physiological Phenomena --- Quality of Health Care --- Public Health --- Environment and Public Health --- Health Care Quality, Access, and Evaluation --- Health Care --- Cohort Studies --- Cross-Sectional Studies --- Estrogen Replacement Therapy --- Methods --- Signs and Symptoms --- Evidence-Based Medicine --- Treatment --- North America --- Americas --- United States --- Evidence-based medicine. --- Clinical Medicine. --- Epidemiologic Studies. --- Investigative Techniques. --- Evidence-Based Practice. --- Pathological Conditions, Signs and Symptoms. --- Hormone Replacement Therapy. --- Climacteric. --- Sexual Development. --- Health Occupations. --- Medicine. --- Drug Therapy. --- Disease. --- Reproductive Physiological Phenomena. --- Health Care Evaluation Mechanisms. --- Epidemiologic Methods. --- Therapeutics. --- Reproductive and Urinary Physiological Phenomena. --- Quality of Health Care. --- Public Health. --- Environment and Public Health. --- Health Care Quality, Access, and Evaluation. --- Delivery of Health Care. --- Cohort Studies. --- Cross-Sectional Studies. --- Estrogen Replacement Therapy. --- Methods. --- Menopause. --- Signs and Symptoms. --- Treatment. --- North America. --- Americas. --- United States.