Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Nucleic acid --- DNA-ligand interactions. --- DNA-protein interactions. --- Interactions ADN-ligand --- Structure. --- -DNA-ligand interactions --- DNA-protein interactions --- DNA-protein binding --- Interactions, DNA-protein --- Protein-DNA interactions --- DNA-ligand interactions --- Protein binding --- Binding, DNA-ligand --- DNA-ligand binding --- Interactions, DNA-ligand --- Ligand binding (Biochemistry) --- Structure

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

"Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--P. [4] of cover.

Quadruplex nucleic acids --- Therapeutic use. --- G-quadruplexes --- G-tetrads --- Guanine quadruplexes --- Tetraplex nucleic acids --- Nucleic acids

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Antineoplastic agents --- Cancer --- Design. --- Chemotherapy. --- Anticancer agents --- Antineoplastic drugs --- Antineoplastics --- Antitumor agents --- Antitumor drugs --- Cytotoxic drugs --- Inhibitors, Neoplasm --- Neoplasm inhibitors --- Drugs --- Treatment --- Chemotherapy

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, the book includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest

Nucleic acids. --- Biomolecules. --- Biological molecules --- Molecules --- Molecular biology --- Polynucleotides --- Biomolecules

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, the book includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software. * Completely updated with expanded discussion of topics such as RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA) * Includes a complete list of resources, including relevant online databases and software * Defines technical lingo for novices.