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This textbook provides the tools for a modern post-graduate introductory course on system reliability theory. It focuses on probabilistic aspects of the theory, including recent results based on signatures, stochastic orders, aging classes, copulas and distortion (or aggregation) functions. The reader requires on an introductory knowledge on probability theory and mathematics. The book serves both for graduate students in mathematics and for engineering students in various disciplines as well as students learning survival analysis, network reliability or simple game theory. Included also are brief introductions to the basic aspects of lifetime modelling, stochastic comparisons, aging classes, mixtures and copula theory. The book develops this knowledge with worked examples and supplies code for the program R so that students can explore its lessons and techniques.

Methodology of economics --- Mathematics --- Business policy --- Planning (firm) --- Production management --- Business management --- Business economics --- financieel management --- industrie --- mathematische modellen --- risk management --- wiskunde

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Methodology of economics --- Mathematics --- Business policy --- Planning (firm) --- Production management --- Business management --- Business economics --- financieel management --- industrie --- mathematische modellen --- risk management --- wiskunde

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Neuropathology --- Human medicine

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Metabolic and Degenerative Diseases of the Central Nervous System is a comprehensive reference work that provides the neuroscience community with valuable, current, and scholarly summaries on every known degenerative disorder. Written by two world-renowned neuropathologists, the book provides an optimal basis for the understanding of metabolic and degenerative diseases of the central nervous system and presents a synthesis that serves the needs of today's investigators in neuropathology, neurology, neuroradiology, neurosurgery, neuropediatrics, general pathology, and geriatrics. This is the only comprehensive authoritative review of the neuropathology of metabolic and neurodegenerative diseases. In the future, genetic engineering is expected to provide effective molecular therapy for the countless diseases currently termed "metabolic" or "degenerative." Metabolic and Degenerative Diseases of the Central Nervous System is intended to provide a sound morphological platform for these forthcoming events. Key Features * Neuropathology of every disease correlated with an overview of the medical and general pathological changes * Authored by neuropathologists with international reputations as educators and scientists * Highlighted with illustrations from the authors' own archives and contributions from colleagues throughout the world.

Neuropathology --- Human medicine

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