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During the past decade, remarkable progress has been made in the development of newer drugs to prevent and treat thromboembolic disorders, such as oral direct anti-Xa and anti-IIa antagonists, as well as oral antiplatelet ADP antagonists with rapid onset and offset. In addition, there has been concentrated effort aimed at identifying novel uses of traditional antithrombotic drugs, such as aspirin, heparin, and oral anticoagulants, as well as combinations of agents, such as more than one antiplatelet, antiplatelet with anticoagulant, antiplatelet with or without thrombolytic. Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition provides updates on various strategies in thrombosis, experimental models, and clinical and recent advances in the discovery and development of novel antithrombotics. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Easy to use and up to date, Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition is an ideal guide for researchers aiming for the future of this vital field, focusing on the prevention of thromboembolic disorders and the protection of the vascular endothelium.

Medicine. --- Cardiology. --- Molecular Medicine. --- Heart --- Internal medicine --- Health Workforce --- Diseases --- Anticoagulants (Medicine) --- Blood platelets --- Thrombolytic therapy --- Fibrinolytic agents --- Thrombolytic therapy - Methods --- Fibrinolytic agents - Therapeutic use --- Heparin - Therapeutic use --- Medicine --- Biology --- Biomedical Research. --- Biological research --- Biomedical research --- Research. --- Heparin

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 This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets.

Blood vessels -- Growth. --- Neovascularization. --- Blood vessels --- Growth. --- Angiogenesis --- Medicine. --- Pharmacy. --- Neurosciences. --- Biotechnology. --- Life sciences. --- Cell biology. --- Biomedicine. --- Biomedicine general. --- Life Sciences, general. --- Cell Biology. --- Blood-vessels --- Growth --- Cytology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Chemical engineering --- Genetic engineering --- Biosciences --- Sciences, Life --- Science --- Chemistry --- Medicine --- Drugs --- Materia medica --- Pharmacology --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Biomedicine, general. --- Health Workforce

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

integrin αvβ3 --- angiogenesis --- anti-apoptosis --- thyroxine --- signal transduction --- driver genes --- tumor microenvironment --- tetrac