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The inappropriate use of antibiotics is a primary cause of the ongoing increase in drugresistance amongst pathogenic bacteria. The resulting decrease in the efficacy of antibiotics threatens the ability to combat infectious diseases. Rapid, point-of-caretests to identify pathogens and better target the appropriate treatment could greatlyimprove the use of antibiotics, yet few such tests are available or being developed, despite the rapid pace of medical innovation. Clearly, something is inhibiting the muchneededdevelopment of new and more convenient diagnostic tools.This study delineates priorities for developing diagnostics to improve antibiotic prescription and use, in order to manage and curb the expansion of drug resistance. Itcalls for new approaches, particularly in the provision of diagnostic devices, and, in doingso, outlines some of the inadequacies in health, science and policy initiatives that haveled to the dearth of such devices. The authors make the case that innovation is clearlyand urgently needed, not only in the technology of diagnosis but also in public policy andmedical practice to support the availability and use of better diagnostic tools.This book explores the complexities of the diagnostics market from the perspective ofboth supply and demand, unearthing interesting bottlenecks: some obvious, some moresubtle. It calls for a broad, multifaceted policy response, and an overhaul of currentpractice, so that the growth of bacterial resistance can be stemmed.

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