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The field of sleep medicine is growing rapidly, and the clinical pharmacology of sleep is gaining much attention from sleep physicians. Many new drugs are in the process of being developed and tested for their possible usefulness in the treatment of sleep disorders. The opportunity for further advancement in this field is very promising. This volume covers the clinical and pharmacological treatment of several important sleep disorders such as insomnia, sleep apnea, narcolepsy, restless legs syndrome, and periodic limb movement syndrome. It further addresses the use of sleep medications in children, adolescents, and in the elderly. It offers a comprehensive overview of the currently available hypnotic medications and covers aspects of chronopharmacology and its implications for the pharmacology of sleep. It also reviews the basic science of sleep and sleep disorders, and thus the potential development of new pharmacological approaches. The book will be useful for physicians, psychopharmacologists, psychiatrists, sleep disorder specialists and other healthcare professionals such as nurses, social workers and graduate medical students.

Sleep disorders. --- Sleep disorders --- Chemotherapy. --- Disorders of sleep --- Nervous system --- Psychology, Pathological --- Diseases --- Toxicology. --- Medicine. --- Psychiatry. --- Pharmacology/Toxicology. --- Medicine/Public Health, general. --- Medicine and psychology --- Mental health --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Health Workforce --- Pharmacology. --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect

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GABA (gamma-aminobutyric acid) is the main neurotransmitter regulating sleep. The majority of drugs presently in use for the treatment of sleep disorders act by enhancing GABAergic neuronal inhibition. This book brings together many of the world’s leading investigators to discuss current and anticipated developments in the areas of geriatric sleep medicine and provides a comprehensive examination of current principles and practice in this field. It is divided into three main sections: Section I: Basic Physiology and Pharmacology Section II: Sleep Science and Circuitry Section III: Neurotherapeutics The areas covered include findings from research investigations various aspects of GABAergic systems and the regulation of sleep. The book is suitable for basic and clinical neuropharmacologists, sleep researchers, psychiatrists, sleep disorders specialists, clinicians, medical students, and all professionals interested in the interdisciplinary areas of sleep and neuropharmacology.

GABA. --- Sleep disorders. --- Sleep. --- GABA --- Sleep --- Sleep disorders --- Aminobutyric Acids --- Therapeutics --- Biological Science Disciplines --- Nervous System Diseases --- Receptors, Amino Acid --- Neurologic Manifestations --- Mental Disorders --- Neurotransmitter Agents --- Psychiatry and Psychology --- Natural Science Disciplines --- Amino Acids --- Molecular Mechanisms of Pharmacological Action --- Signs and Symptoms --- Physiological Effects of Drugs --- Diseases --- Butyric Acids --- Receptors, Neurotransmitter --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Pharmacology --- gamma-Aminobutyric Acid --- Sleep Disorders --- GABA Agents --- Drug Therapy --- Physiology --- Receptors, GABA --- Pharmacologic Actions --- Disciplines and Occupations --- Amino Acids, Peptides, and Proteins --- Acids, Acyclic --- Receptors, Cell Surface --- Pathological Conditions, Signs and Symptoms --- Carboxylic Acids --- Chemical Actions and Uses --- Membrane Proteins --- Chemicals and Drugs --- Proteins --- Organic Chemicals --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Physiological effect. --- Physiological aspects. --- Disorders of sleep --- Gamma-aminobutyric acid --- Medicine. --- Human physiology. --- Biomedicine. --- Human Physiology. --- Nervous system --- Psychology, Pathological --- Amino acid neurotransmitters --- Aminobutyric acid --- Human biology --- Medical sciences --- Human body

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This book offers a compilation of papers on the role of melanin-concentrating hormone (MCH) in sleep, sleep disorders and neuroendocrine functions. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from the anatomical structure and physiology of the MCH system to the connection with other systems influencing sleep and diseases like anxiety and depression. The potential of MCHR-1 antagonists as anxiolytic/antidepressant drugs is also reviewed. The book will represent an interdisciplinary guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, psychologists, and behavioral sleep medicine specialists. .

Sleep substances. --- Neuropeptides. --- Sleep --- Physiological aspects. --- Medicine. --- Molecular biology. --- Neurosciences. --- Biomedicine. --- Molecular Medicine. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Brain peptides --- Nerve tissue proteins --- Neurotransmitters --- Peptides --- Endogeneous sleep factors --- Endogeneous sleep substances --- Sleep inducing substances --- Sleep peptides --- Sleep promoting substances --- Neurosecretion --- Health Workforce

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The field of sleep medicine is growing rapidly, and the clinical pharmacology of sleep is gaining much attention from sleep physicians. Many new drugs are in the process of being developed and tested for their possible usefulness in the treatment of sleep disorders. The opportunity for further advancement in this field is very promising. This volume covers the clinical and pharmacological treatment of several important sleep disorders such as insomnia, sleep apnea, narcolepsy, restless legs syndrome, and periodic limb movement syndrome. It further addresses the use of sleep medications in children, adolescents, and in the elderly. It offers a comprehensive overview of the currently available hypnotic medications and covers aspects of chronopharmacology and its implications for the pharmacology of sleep. It also reviews the basic science of sleep and sleep disorders, and thus the potential development of new pharmacological approaches. The book will be useful for physicians, psychopharmacologists, psychiatrists, sleep disorder specialists and other healthcare professionals such as nurses, social workers and graduate medical students.

Hygiene. Public health. Protection --- Pharmacology. Therapy --- Psychiatry --- psychiatrie --- farmacologie --- gezondheidszorg --- toxicologie

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This book offers a compilation of papers on the role of melanin-concentrating hormone (MCH) in sleep, sleep disorders and neuroendocrine functions. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from the anatomical structure and physiology of the MCH system to the connection with other systems influencing sleep and diseases like anxiety and depression. The potential of MCHR-1 antagonists as anxiolytic/antidepressant drugs is also reviewed. The book will represent an interdisciplinary guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, psychologists, and behavioral sleep medicine specialists. .

Molecular biology --- Neuropathology --- Human medicine --- neurologie --- geneeskunde --- moleculaire biologie