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La notion de biomarqueur est de plus en plus utilisee en oncologie. Elle consiste a identifier des elements biologiques pouvant avoir une utilite diagnostique, pronostique et therapeutique ; Les biomarqueurs sont au cœur du Plan Cancer et representent une evolution majeure en oncologie ouvrant la voie de la personnalisation therapeutique. Dans cet ouvrage, sera presentee la definition des biomarqueurs puis leur declinaison dans les domaines de la genetique tumorale, du polymorphisme genetique avec leurs consequences sur les therapies du cancer. Les biomarqueurs innovants en matiere de diagnost

Tumor markers --- Diagnostic use. --- Molecular diagnosis

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This book is a comprehensive guide to the techniques, clinical applications, and benefits of the different forms of liquid biopsy employed in patients with a variety of tumor types, including lung, breast and colorectal cancer. Offering detailed explanations, it discusses the how changes in tumors can be tracked using these cutting-edge technologies, which enable the detection and analysis of diverse circulating biomarkers: tumor cells, tumor DNA, tumor RNA (free or in exosomes), and fluid biomarkers identifiable by means of targeted proteomics. The use of such advanced technologies is enabling us to tackle questions and problems in a way that was not possible just a few years ago. We now have at our disposal an effective means of overcoming the problem of intratumor heterogeneity, which has limited the value of conventional biopsy approaches. As a consequence, oncology practice is about to change radically, toward truly personalized precision medicine. This book provides both clinicians and researchers with a thorough and up-to-date overview of progress in the field.

Tumors --- Diagnosis. --- Oncology  . --- Pathology. --- Cancer research. --- Oncology. --- Cancer Research. --- Cancer research --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive

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Oncology. Neoplasms --- Pathology --- pathologie --- oncologie