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This book is the first volume of a two-volume set summarizing 40 years of key research findings directly related to metal-resistant Cupriavidus/Ralstonia (Betaproteobacteria). In this first volume, the historical and geographical context of these bacteria, which are mostly found in industrial and polluted environments linked to zinc and other non-ferrous metallurgy, is sketched to illustrate the interactions between bacteria and human activities and the possible evolutionary consequences on bacterial genomes especially as far as the association of metal resistance genes with mobile genetic elements is concerned. A detailed description of the response and underlying genetic determinants of type strain Cupriavidus metallidurans CH34 to a variety of metals is provided. With high level resistance to cadmium, chromate, cobalt, copper, mercury, nickel, lead and zinc mediated by well-known genes for detoxification carried by its megaplasmids pMOL28 and pMOL30. This description is complemented with the genomic context of the metal response genes in C. metallidurans CH34 with a focus on its mobilome including insertion sequence elements, transposons, integrative and conjugative elements and genomic islands. In addition, in the second volume, structural and catalytic data from bacterial primary and secondary transporters (P-ATPases, tripartite chemiosmotic cation/proton efflux systems, cation diffusion facilitators, Major Facilitator Superfamily and some minor categories) are outlined and detailed for the corresponding C. metallidurans proteins. The available three-dimensional structures of C. metallidurans proteins are reviewed in detail, including RND and membrane fusion proteins (from tripartite chemiosmotic cation/proton efflux systems), sigma and anti-sigma regulatory proteins of the cnr efflux system (resistance to cobalt and nickel) and various periplasmic proteins mainly involved in the response to copper and mercury.

Chemistry. --- Applied Microbiology. --- Microbiology. --- Biogeosciences. --- Environmental Engineering/Biotechnology. --- Life sciences. --- Biotechnology. --- Chimie --- Microbiologie --- Sciences de la vie --- Biotechnologie --- Carrier proteins. --- Metal ions. --- Proteins -- Structure. --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Proteins --- Structure. --- Binding proteins --- Transport proteins --- Geobiology. --- Environmental engineering. --- Biological transport --- Protein binding --- Ions --- Chemical engineering --- Genetic engineering --- Microbial biology --- Microorganisms --- Monograph --- Environmental control --- Environmental effects --- Environmental stresses --- Engineering --- Environmental health --- Environmental protection --- Pollution --- Sustainable engineering --- Earth sciences --- Biosphere

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This book is the second volume of a two-volume set summarizing 40 years of key research findings directly related to metal-resistant Cupriavidus/Ralstonia (Betaproteobacteria). In this second volume, the structural and catalytic data from bacterial primary and secondary transporters (P-ATPases, tripartite chemiosmotic cation/proton efflux systems, cation diffusion facilitators, Major Facilitator Superfamily and some minor categories) are outlined and detailed for the corresponding C. metallidurans proteins. The available three-dimensional structures are reviewed in detail, including RND and membrane fusion proteins (from tripartite chemiosmotic cation/proton efflux systems), sigma and anti-sigma regulatory proteins of the cnr efflux system (resistance to cobalt and nickel) and various periplasmic proteins mainly involved in the response to copper and mercury. In addition, the first volume sketches the historical and geographical context of these bacteria, which are mostly found in industrial and polluted environments linked to zinc and other non-ferrous metallurgy, to illustrate the interactions between bacteria and human activities and the possible evolutionary consequences on bacterial genomes especially as far as the association of metal resistance genes with mobile genetic elements is concerned. It provides a detailed description of the response and underlying genetic determinants of type strain Cupriavidus metallidurans CH34 to a variety of metals. With high level resistance to cadmium, chromate, cobalt, copper, mercury, nickel, lead and zinc mediated by well-known genes for detoxification carried by its megaplasmids pMOL28 and pMOL30. This description is complemented with the genomic context of the metal response genes in C. metallidurans CH34 with a focus on its mobilome including insertion sequence elements, transposons, integrative and conjugative elements and genomic islands.

Chemistry. --- Applied Microbiology. --- Microbiology. --- Biogeosciences. --- Life sciences. --- Chimie --- Microbiologie --- Sciences de la vie --- Carrier proteins. --- Metal ions. --- Proteins -- Structure. --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Proteins --- Structure. --- Binding proteins --- Transport proteins --- Geobiology. --- Ions --- Biological transport --- Protein binding --- Microbial biology --- Microorganisms --- Monograph --- Earth sciences --- Biosphere

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Quatrième de couverture : "La 4e édition française d'un grand classique La traduction en français de la huitième édition du Prescott's Microbiology, est un ouvrage de référence qui décrit la microbiologie dans ses aspects fondamentaux, médicaux, écologiques, alimentaires et industriels. Dans cette nouvelle édition, une attention particulière est apportée à l'évolution des microbes, à leur diversité et leur écologie, à leur pouvoir pathogène, aux épidémies contemporaines et aux moyens de les combattre. Des outils informatiques et des animations en 3D La grande nouveauté réside en des outils informatiques et des animations en 3D accessibles sur le Web. Sur ce site, on peut trouver également de la documentation complémentaire, soit pointue, soit de vulgarisation. Les nouveautés de cette édition Parmi les thèmes nouveaux de cette édition, on retiendra l'attention portée sur les biocarburants d'origine microbienne, l'influence des microbes sur le changement climatique, l'explosion au XXIe siècle des techniques de génomique, la microbiologie de l'eau, la description du virus Hl N1. Nous pointerons également l'ajout des questions qui viennent illustrer la matière à partir d'articles pointus. Elles incitent les étudiants à consulter la littérature scientifique et à tester leurs connaissances. Enfin, la valeur pédagogique des diagrammes de concepts est fortement appréciée par les étudiants. Traduction de la 8e édition américaine Jacques Coyette est microbiologiste et docteur en sciences biomédicales expérimentales de l'Université de Liège. Il est chargé de cours honoraire de cette même université. Il a enseigné la biologie générale au premier cycle universitaire ainsi que la bactériologie fondamentale et la biochimie microbienne au second. Max Mergeay est microbiologiste et docteur en sciences chimiques de l'Université Libre de Bruxelles. Il est actuellement professeur honoraire de cette même université et collaborateur scientifique à l'Université de Mons. Pendant 30 ans, il a animé au Centre d'Etudes de l'Energie Nucléaire de Mol (Belgique) un groupe de recherches sur la microbiologie spatiale."

Microbiology --- Molecular biology --- Microbial ecology --- Microbiologie --- Biologie moléculaire --- Ecologie microbienne --- Textbooks --- Manuels d'enseignement supérieur --- Microbiologie. --- Microbiology. --- Molecular Biology --- Bacteria --- Virus --- viruses --- Micro-organisme --- microorganisms --- Génétique --- genetics --- Immunologie --- Immunology --- Métabolisme --- Metabolism --- Croissance --- Growth --- Biologie moléculaire --- Manuels d'enseignement supérieur --- viruses. --- Microbiology - handbooks --- Microbiology - textbooks --- Molecular Biology - textbooks --- Microbiology - Textbooks --- Bacteria. --- genetics. --- Growth. --- Immunology. --- Metabolism. --- microorganisms.