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The extracellular matrix : an overview
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ISBN: 3642165540 9786613080899 3642165559 1283080893 Year: 2011 Publisher: Berlin ; Heidelberg : Springer-Verlag,

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Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment.  Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.


Digital
The Extracellular Matrix: an Overview
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ISBN: 9783642165559 Year: 2011 Publisher: Berlin, Heidelberg Springer Berlin Heidelberg

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Periodical
Biology of extracellular matrix
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Year: 1986 Publisher: Orlando New York Toronto Academic Press

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Regulation of matrix accumulation
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ISBN: 0124874258 Year: 1986 Publisher: Orlando New York Toronto Academic Press

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Matrix metalloproteinases
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ISBN: 1281057045 9786611057046 0080535984 0125450907 Year: 1998 Publisher: San Diego, California : Academic Press,

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The chapters in this book thoroughly cover the structure, regulation, and function of matrix metalloproteinases, and provide information on the latest strategies to inhibit enzyme activity. This work will be an indispensable reference tool for investigators with an interest in extracellular matrix biology, matrix turnover, enzymology and biochemistry of proteinases, developmental biology, pathology, and therapeutic interventions.Key Features* Provides state-of-the-art information on a field with broad implications to many areas of biology* Includes detailed coverage of the stru

Organization and assembly of plant and animal extracellular matrix
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ISBN: 0120440601 1299193455 0323153224 Year: 1990 Publisher: San Diego, Calif. Academic Press

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Integrins : molecular and biological responses to the extracellular matrix
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ISBN: 0121711609 0080917291 9786613931337 1283618885 9780121711603 Year: 1994 Publisher: New York, NY : Academic Press,

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Integrins


Book
Extracellular matrix degradation
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ISBN: 3642168604 3642168612 Year: 2011 Publisher: New York : Springer,

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Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Biology of Extracellular Matrix series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases, meprins, serine proteases, and elastases. The volume also discusses the domains responsible for specific biochemical characteristics of the proteases and the physical interactions that occur when the protease interacts with substrate. The topics covered in this volume provide an important context for understanding the role that matrix-degrading proteases play in normal tissue remodeling and in diseases such as cancer and lung disease. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.

Keywords

Collagen. --- Connective Tissue. --- Connective tissues -- Congresses. --- Extracellular matrix. --- Polysaccharides. --- Extracellular Space --- Metalloendopeptidases --- Membrane Glycoproteins --- Antigens, Surface --- Proteins --- Amino Acids, Peptides, and Proteins --- Cellular Structures --- Endopeptidases --- Glycoproteins --- Membrane Proteins --- Antigens --- Metalloproteases --- Peptide Hydrolases --- Biological Factors --- Cells --- Chemicals and Drugs --- Hydrolases --- Anatomy --- Enzymes --- Enzymes and Coenzymes --- Cell Adhesion Molecules --- Extracellular Matrix --- Matrix Metalloproteinases --- Tissue Inhibitor of Metalloproteinases --- Biology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Cytology --- Physiology --- Cement substance (Anatomy) --- Ground substance (Anatomy) --- Ground substance (Histology) --- Intercellular matrix --- Interstitial substance --- Matrix, Extracellular --- Life sciences. --- Molecular biology. --- Biochemistry. --- Proteins. --- Cell biology. --- Life Sciences. --- Cell Biology. --- Biochemistry, general. --- Protein Science. --- Molecular Medicine. --- Connective tissues --- Extracellular space --- Cytology. --- Medicine. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Cell biology --- Cellular biology --- Cytologists --- Composition --- Health Workforce --- Proteins . --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Proteids --- Polypeptides --- Proteomics

The vascular smooth muscle cell
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ISBN: 1281054453 9786611054458 0080543502 0126323100 9780126323108 9780080543505 Year: 1995 Publisher: San Diego Academic Press

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In the last several years, the development of reagents that recognize smooth muscle-specific proteins has enabled researchers to identify smooth muscle cells (SMC) in tissue undergoing both differentiation and repair. These developments have led to increased research on SMC. The latest volume in the Biology of the Extracellular Matrix Series takes a current and all-encompassing look at this growing area of research. Devoted entirely to the subject of SMC, the book covers a diversity of topics-from SMC architecture and contractility to differentiation and gene expression in development. It also


Book
The Extracellular Matrix: an Overview
Authors: ---
ISBN: 9783642165559 Year: 2011 Publisher: Berlin, Heidelberg Springer Berlin Heidelberg

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Abstract

Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series Biology of Extracellular Matrix  provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment.  Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

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