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This book discusses the importance of oxidative stress, related biomarkers, and its diagnostic methods including bio-analytical and advanced detection systems. Oxidative stress is associated with diminished capacity of a biological system to overcome the overproduction of reactive oxygen species. Since oxidative stress has been suggested as a causative factor in many diseases, its prevention is vital, and there is an urgent need for oxidative stress monitoring using in vitro and in vivo models. Interdisciplinary approaches have lead to the development of various oxidative stress monitoring models for real-world clinical and biomedical applications. The development of such methods requires a broad understanding of biology, chemistry, molecular biology, immunology and microbiology. As such, the book is a valuable resource for students, researchers and clinicians interested in the fundamental as well as applied aspects of oxidative stress associated diseases.

Life sciences. --- Human physiology. --- Biomedical engineering. --- Cell physiology. --- Oxidative stress. --- Biology --- Nanotechnology. --- Life Sciences. --- Oxidative Stress. --- Human Physiology. --- Cell Physiology. --- Biomedical Engineering/Biotechnology. --- Biological Techniques. --- Nanotechnology and Microengineering. --- Molecular technology --- Nanoscale technology --- Cell function --- Clinical engineering --- Medical engineering --- Biosciences --- Sciences, Life --- Technique. --- Oxidation-reduction reaction --- Stress (Physiology) --- Science --- Cytology. --- Cytology --- Engineering. --- Research --- Methodology. --- Construction --- Industrial arts --- Technology --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Physiology --- Human biology --- Medical sciences --- Human body --- Biology—Technique. --- High technology

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Nanotechnology. --- Molecular technology --- Nanoscale technology --- High technology

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Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-Oncology: From Basic Research to Advanced Study analyzes the emerging the field of cardio-oncology, reviewing recent advancements in the field, discussing how to monitor and treat cancer survivors for cardiotoxicity, and identifying potential cardiac side effects in novel cancer therapies. By adopting a translational approach, the book first comprehensively covers the basic science, mechanisms and concepts, which is followed by advanced state-of-art of cardio-oncology. Other sections cover tyrosine kinase inhibitors, Anthracyclines, and biomarkers in cardiotoxicity induced by chemotherapeutic drugs, noninvasive cardiovascular imaging techniques, radiotherapy induced cardiovascular, and more. [...] Both traditional chemotherapeutic agents and newer therapies have demonstrated profound cardiovascular toxicities. It is important to understand the mechanisms of these toxicities to establish strategies for the prevention and management of complications—arrhythmias, heart failure, and even death.

Cardiovascular toxicology. --- Cardiotoxicity. --- Drug-Related Side Effects and Adverse Reactions. --- Antineoplastic Agents. --- Radiotherapy --- Anticancer Agents --- Antineoplastic Drugs --- Antineoplastics --- Antitumor Agents --- Antitumor Drugs --- Cancer Chemotherapy Agents --- Cancer Chemotherapy Drugs --- Chemotherapeutic Anticancer Agents --- Chemotherapeutic Anticancer Drug --- Anticancer Agent --- Antineoplastic --- Antineoplastic Agent --- Antineoplastic Drug --- Antitumor Agent --- Antitumor Drug --- Cancer Chemotherapy Agent --- Cancer Chemotherapy Drug --- Agent, Anticancer --- Agent, Antineoplastic --- Agent, Antitumor --- Agent, Cancer Chemotherapy --- Agents, Anticancer --- Agents, Antineoplastic --- Agents, Antitumor --- Agents, Cancer Chemotherapy --- Agents, Chemotherapeutic Anticancer --- Chemotherapy Agent, Cancer --- Chemotherapy Agents, Cancer --- Chemotherapy Drug, Cancer --- Chemotherapy Drugs, Cancer --- Drug, Antineoplastic --- Drug, Antitumor --- Drug, Cancer Chemotherapy --- Drug, Chemotherapeutic Anticancer --- Drugs, Antineoplastic --- Drugs, Antitumor --- Drugs, Cancer Chemotherapy --- Cytotoxins --- Interferon Inducers --- Anticarcinogenic Agents --- Adverse Drug Event --- Adverse Drug Reaction --- Drug Side Effects --- Drug Toxicity --- Side Effects of Drugs --- Toxicity, Drug --- Adverse Drug Events --- Adverse Drug Reactions --- Drug Event, Adverse --- Drug Events, Adverse --- Drug Reaction, Adverse --- Drug Reactions, Adverse --- Drug Related Side Effects and Adverse Reactions --- Drug Side Effect --- Drug Toxicities --- Effects, Drug Side --- Reactions, Adverse Drug --- Side Effect, Drug --- Side Effects, Drug --- Toxicities, Drug --- Drug Therapy --- Pharmaceutical Preparations --- Contraindications, Drug --- Drug Interactions --- Clinical Trials, Phase IV as Topic --- Cardiac Toxicity --- Cardiac Toxicities --- Cardiotoxicities --- Toxicity, Cardiac --- Cardiovascular toxicity --- Toxicology --- adverse effects. --- adverse effects --- toxicity --- Heart --- Effect of drugs on. --- Cardiovascular pharmacology --- Drug effects --- Cardiotoxicity --- Drug-Related Side Effects and Adverse Reactions --- Antineoplastic Agents --- adverse effects ǂ0 (DNLM)D011878Q000009

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Treatment Landscape of Targeted Therapies in Oncology: Challenges and Opportunities provides up-to-date knowledge on antitumor-targeted therapies and immunotherapy. The book's chapters are written by researchers dynamically working/focusing on cancer treatment. The content is designed to help those who are new to the field (beginners) and various specialized scientists and researchers involved in cancer research. For decades, the hallmark of cancer treatment has been conventional chemotherapy. But with the rapid increase in our understanding of the immune system, more and more small molecules, peptides, recombinant antibodies, vaccines and cellular therapeutic modalities are being applied to manipulate the immune response for cancer treatment.

Molecular Targeted Therapy. --- Immunotherapy. --- Neoadjuvant Therapy. --- Drug Therapy. --- Antineoplastic Agents. --- Neoplasms --- therapy. --- Anticancer Agents --- Antineoplastic Drugs --- Antineoplastics --- Antitumor Agents --- Antitumor Drugs --- Cancer Chemotherapy Agents --- Cancer Chemotherapy Drugs --- Chemotherapeutic Anticancer Agents --- Chemotherapeutic Anticancer Drug --- Anticancer Agent --- Antineoplastic --- Antineoplastic Agent --- Antineoplastic Drug --- Antitumor Agent --- Antitumor Drug --- Cancer Chemotherapy Agent --- Cancer Chemotherapy Drug --- Agent, Anticancer --- Agent, Antineoplastic --- Agent, Antitumor --- Agent, Cancer Chemotherapy --- Agents, Anticancer --- Agents, Antineoplastic --- Agents, Antitumor --- Agents, Cancer Chemotherapy --- Agents, Chemotherapeutic Anticancer --- Chemotherapy Agent, Cancer --- Chemotherapy Agents, Cancer --- Chemotherapy Drug, Cancer --- Chemotherapy Drugs, Cancer --- Drug, Antineoplastic --- Drug, Antitumor --- Drug, Cancer Chemotherapy --- Drug, Chemotherapeutic Anticancer --- Drugs, Antineoplastic --- Drugs, Antitumor --- Drugs, Cancer Chemotherapy --- Cytotoxins --- Interferon Inducers --- Anticarcinogenic Agents --- Therapy, Drug --- Chemotherapy --- Pharmacotherapy --- Chemotherapies --- Drug Therapies --- Pharmacotherapies --- Therapies, Drug --- Disease --- Pharmaceutical Preparations --- Pharmacologic Actions --- Neoadjuvant Chemoradiation --- Neoadjuvant Chemoradiation Therapy --- Neoadjuvant Chemoradiation Treatment --- Neoadjuvant Chemoradiotherapy --- Neoadjuvant Chemotherapy --- Neoadjuvant Chemotherapy Treatment --- Neoadjuvant Radiation --- Neoadjuvant Radiation Therapy --- Neoadjuvant Radiation Treatment --- Neoadjuvant Radiotherapy --- Neoadjuvant Systemic Therapy --- Neoadjuvant Systemic Treatment --- Neoadjuvant Treatment --- Chemoradiation Therapy, Neoadjuvant --- Chemoradiation Treatment, Neoadjuvant --- Chemoradiation, Neoadjuvant --- Chemoradiotherapy, Neoadjuvant --- Chemotherapy Treatment, Neoadjuvant --- Chemotherapy, Neoadjuvant --- Neoadjuvant Chemoradiation Therapies --- Neoadjuvant Chemoradiation Treatments --- Neoadjuvant Chemoradiations --- Neoadjuvant Chemoradiotherapies --- Neoadjuvant Chemotherapies --- Neoadjuvant Chemotherapy Treatments --- Neoadjuvant Radiation Therapies --- Neoadjuvant Radiation Treatments --- Neoadjuvant Radiations --- Neoadjuvant Radiotherapies --- Neoadjuvant Systemic Therapies --- Neoadjuvant Systemic Treatments --- Neoadjuvant Therapies --- Neoadjuvant Treatments --- Radiation Therapy, Neoadjuvant --- Radiation Treatment, Neoadjuvant --- Radiation, Neoadjuvant --- Radiotherapy, Neoadjuvant --- Systemic Therapy, Neoadjuvant --- Systemic Treatment, Neoadjuvant --- Therapy, Neoadjuvant --- Therapy, Neoadjuvant Chemoradiation --- Therapy, Neoadjuvant Radiation --- Therapy, Neoadjuvant Systemic --- Treatment, Neoadjuvant --- Treatment, Neoadjuvant Chemoradiation --- Treatment, Neoadjuvant Chemotherapy --- Treatment, Neoadjuvant Radiation --- Treatment, Neoadjuvant Systemic --- Immunotherapies --- Combined Antibody Therapeutics --- Immunity, Active --- Immunologic Techniques --- Targeted Molecular Therapy --- Molecular Targeted Therapies --- Molecular Therapy, Targeted --- Targeted Molecular Therapies --- Targeted Therapy, Molecular --- Therapy, Molecular Targeted --- Therapy, Targeted Molecular --- drug therapy --- therapeutic use --- Cancer --- Treatment --- Technological innovations. --- Immunotherapy --- Molecular Targeted Therapy --- therapy

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The book introduces the basic concepts of nanotechnology and the various technologies to characterize nanomaterials. It also covers the nanostructural features of mammalian cells/tissues and related nanomechanical properties. In addition, the book comprehensively describes the current state-of-the-art and future perspectives of nanotechnology in biosensors. It also discusses the potential of nanotechnology for delivering the diverse cancer therapeutics and illustrates its limitation due to the potential toxicity associated with oxidative stress. It also highlights the ethical issues and translational aspects related to nanotechnology. Finally, it summarizes the applications of nanotechnology in animal biotechnology, the recent perspectives and future challenges of nanomedicines. The content of the book are beneficial for the undergraduate, postgraduate and doctoral students as well the professionals working in the area of nanotechnology and nanomedicines.

Professional ethics. Deontology --- Histology. Cytology --- Human biochemistry --- Immunology. Immunopathology --- Electrical engineering --- Biotechnology --- anti-oxidantia --- vrije radicalen --- medische biochemie --- nanotechniek --- biosensoren --- biomedische wetenschappen --- biotechnologie --- cytologie --- bio-ethiek --- medische ethiek --- immunochemie --- enzymen