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One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription. In addition to environmental aspects (including phytoremediation), the book treats the pathophysiology of metal deficiency and overload in relation to disease.

Metalloproteins --- Metals --- Homeostasis --- Molecular Biology --- Metal ions --- Molecular genetics --- Métalloprotéines --- Génétique moléculaire --- Homéostasie --- metabolism --- Metabolism --- Metabolic detoxification --- Physiological Processes --- Proteins --- Biochemistry --- Inorganic Chemicals --- Genetics --- Biological Science Disciplines --- Chemistry --- Biology --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Physiological Phenomena --- Natural Science Disciplines --- Phenomena and Processes --- Disciplines and Occupations --- Biology - General --- Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physical Sciences & Mathematics --- Disorders --- Metal --- Metabolic detoxification. --- Disorders. --- Metabolism. --- Metallic elements --- Life sciences. --- Biochemistry. --- Cell biology. --- Microbiology. --- Plant physiology. --- Life Sciences. --- Biochemistry, general. --- Cell Biology. --- Biomedicine general. --- Plant Physiology. --- Chemical elements --- Ores --- Metallurgy --- Cytology. --- Medicine. --- Botany --- Plants --- Physiology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Microbial biology --- Microorganisms --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Composition --- Health Workforce --- Biomedicine, general. --- Medicine --- Biomedical Research. --- Research. --- Biological research --- Biomedical research

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription. In addition to environmental aspects (including phytoremediation), the book treats the pathophysiology of metal deficiency and overload in relation to disease.

General microbiology --- Histology. Cytology --- General biochemistry --- Plant physiology. Plant biophysics --- Human biochemistry --- systematische plantkunde --- medische biochemie --- biochemie --- microbiologie --- cytologie --- histologie --- moleculaire biologie