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This book constitutes the thoroughly refereed post-workshop proceedings of the International Workshop on Brain Lesion, as well as the challenges on Brain Tumor Segmentation (BRATS), Ischemic Stroke Lesion Image Segmentation (ISLES), and the Mild Traumatic Brain Injury Outcome Prediction (mTOP), held in Athens, October 17, 2016, in conjunction with the International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2016. The 26 papers presented in this volume were carefully reviewed. They present the latest advances in segmentation, disease prognosis and other applications to the clinical context. .

Computer science. --- Health informatics. --- Algorithms. --- Data mining. --- Artificial intelligence. --- Image processing. --- Pattern recognition. --- Computer Science. --- Image Processing and Computer Vision. --- Pattern Recognition. --- Artificial Intelligence (incl. Robotics). --- Algorithm Analysis and Problem Complexity. --- Data Mining and Knowledge Discovery. --- Health Informatics. --- Informatics --- Science --- Pictorial data processing --- Picture processing --- Processing, Image --- Imaging systems --- Optical data processing --- AI (Artificial intelligence) --- Artificial thinking --- Electronic brains --- Intellectronics --- Intelligence, Artificial --- Intelligent machines --- Machine intelligence --- Thinking, Artificial --- Bionics --- Cognitive science --- Digital computer simulation --- Electronic data processing --- Logic machines --- Machine theory --- Self-organizing systems --- Simulation methods --- Fifth generation computers --- Neural computers --- Algorithmic knowledge discovery --- Factual data analysis --- KDD (Information retrieval) --- Knowledge discovery in data --- Knowledge discovery in databases --- Mining, Data --- Database searching --- Algorism --- Algebra --- Arithmetic --- Design perception --- Pattern recognition --- Form perception --- Perception --- Figure-ground perception --- Clinical informatics --- Health informatics --- Medical information science --- Information science --- Medicine --- Foundations --- Data processing --- Computer vision. --- Optical pattern recognition. --- Computer software. --- Medical records --- Artificial Intelligence. --- Data processing. --- EHR systems --- EHR technology --- EHRs (Electronic health records) --- Electronic health records --- Electronic medical records --- EMR systems --- EMRs (Electronic medical records) --- Information storage and retrieval systems --- Software, Computer --- Computer systems --- Pattern perception --- Perceptrons --- Visual discrimination --- Machine vision --- Vision, Computer --- Artificial intelligence --- Image processing --- Pattern recognition systems --- Medical care --- Brain --- Tumors --- Wounds and injuries --- Cerebrum --- Mind --- Central nervous system --- Head --- Optical data processing. --- Optical computing --- Visual data processing --- Integrated optics --- Photonics --- Computers --- Optical equipment --- Pattern recognition systems. --- Medical informatics. --- Computer Vision. --- Automated Pattern Recognition. --- Pattern classification systems --- Pattern recognition computers --- Computer vision