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This handbook has been designed to provide a comprehensive and state-of-the art review and update of the major issues and challenges specific to fine needle aspiration (FNA) and small tissue core biopsies, which have emerged as primary modalities in establishing a definitive cancer diagnosis in the field of anatomic pathology, both in the U.S. and worldwide. Making an accurate diagnosis from a limited sample can be quite challenging yet crucial to patient care. The handbook, using the most current and evidence-based resources, will 1) emphasize a triple test (clinical, radiologic, and cytologic/histologic correlation); 2) stress the importance of cellblock preparation/small tissue core biopsy in modern cytopathology; 3) include over 100 diagnostic immunostaining panels/tables to address the utility and importance of ancillary studies; 4) incorporate relevant FISH and molecular tests into each chapter; and 5) summarize the pearls and pitfalls of FNA/small tissue biopsies at the beginning of each chapter. The book also includes highly practical presentations of typical case scenarios seen in an anatomic pathology laboratory.  These are in the form of case presentations with step-by-step expert analysis.  Sample cases include common but challenging situations, such as work-up of a tumor of unknown origin, evaluation of well-differentiated malignant tumors vs. benign/reactive lesions, identification of newly described tumor entities, and implementation of best practice in immunohistochemistry and molecular testing in a difficult case. Handbook of Practical Fine Needle Aspiration and Small Tissue Biopsies is written by recognized experts in their fields and provides a unique and valuable resource in the field of cytopathology, both for those currently in training and for those already in clinical practice at various skill levels.  It represents a new, comprehensive yet concise resource on these timely and critical topics.

Needle biopsy --- Medicine. --- Pathology. --- Medicine & Public Health. --- Aspiration biopsy --- Biopsy, Needle --- Fine-needle aspiration biopsy --- Needle aspiration biopsy --- Puncture biopsy --- Suction biopsy --- Biopsy --- Cytodiagnosis --- Paracentesis --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive

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As in the second edition, the third edition of Handbook of Practical Immunohistochemistry - Frequently Asked Questions is written in a question and answer (Q&A) format and intended to be a practical, user-friendly, quick reference for information related to using the most up-to-date immunohistochemistry and in situ hybridization in clinical diagnosis. The new edition demonstrates a significant revision and improvement over the second edition. Five new chapters have been added that cover the following: 1) Immunohistochemistry: Leica's perspective; 2) Immunohistochemistry: Maixin perspective; 3) RNA in situ hybridization: Applications in anatomic pathology; 4) Applications of rapid immunohistochemistry on frozen tissue sections during intraoperative pathologic diagnosis; and 5) Cutaneous lymphomas. In addition to extensive additions and changes, over 150 new questions and answers were added throughout this new edition. All chapters have been updated to include relevant new questions, new markers, more refined IHC panels, representative pictures, and current references. An extensive set of high-quality color pictures and diagnostic algorithms, if available, is included in each chapter to illustrate some of the key antibodies, including many recently discovered and substantiated antibodies used in that chapter. Written by experts in the field, Handbook of Practical Immunohistochemistry Third Edition is a comprehensive and practical guide for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.

Pathology --- pathologie --- Immunohistochemistry. --- Immunohistochemistry