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Industrial biotransformations
Authors: --- ---
ISBN: 3527300945 Year: 2000 Publisher: Weinheim Wiley-VCH

Industrial biotransformations
Authors: --- ---
ISBN: 9783527608188 9783527310012 128072336X 3527608184 3527607900 Year: 2006 Publisher: Weinheim Wiley-VCH

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Abstract

The completely revised second edition of this user-friendly and application-oriented overview of one-step biotransformations of industrial importance.Based on extensive literature and patent research, this book is unique in arranging each process in a systematic way to allow for easy comparison. All the chapters have been rewritten, with all the processes updated and more than 30 new processes added. Each set of data is accompanied by key literature citations, supported by flow sheets where available, reduced to their significant elements. In addition, an extensive index classified by substrates, products, enzymes, and companies provides direct access to each process, organized according to enzyme class. Biotechnologists, biochemists, microbiologists, process engineers and those working in the chemical and biotechnological industries will find here all the significant parameters characterizing both the biotransformation and the process.


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Biocatalysis for the pharmaceutical industry : discovery, development, and manufacturing
Authors: --- ---
ISBN: 1282382098 9786612382093 047082316X 0470823151 Year: 2009 Publisher: Singapore ; Hoboken : Wiley,

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Abstract

Biocatalysis is rapidly evolving into a key technology for the discovery and production of chemicals, especially in the pharmaceutical industry, where high yielding chemo-, regio-, and enantioselective reactions are critical. Taking the latest breakthroughs in genomics and proteomics into consideration, Biocatalysis for the Pharmaceutical Industry concisely yet comprehensively discusses the modern application of biocatalysis to drug discovery, development, and manufacturing. Written by a team of leading experts, the book offers deep insight into this cutting edge field. Covers a wide range of topics in a systematic manner with an emphasis on industrial applications Provides a thorough introduction to the latest biocatalysts, modern expression hosts, state-of-the-art directed evolution, high throughput screening, and bioprocess engineering Addresses frontier subjects such as emerging enzymes, metabolite profiling, combinatorial biosynthesis, metabolic engineering, and autonomous enzymes for the synthesis and development of chiral molecules, drug metabolites, and semi-synthetic medicinal compounds and natural product analogs Highlights the impact of biocatalysis on green chemistry Contains numerous graphics to illustrate concepts and techniques Biocatalysis for the Pharmaceutical Industry is an essential resource for scientists, engineers, and R&D policy makers in the fine chemical, pharmaceutical, and biotech industries. It is also an invaluable tool for academic researchers and advanced students of organic and materials synthesis, chemical biology, and medicinal chemistry.

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