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The Handbook of Neurotoxicity is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments – to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners including those 1) afforded by therapeutic agents – clinical and preclinical; or 2) by non-drug means, such as exercise. The amorphous term ‘neurotoxin’ is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction – akin to a neurotoxin’s effect. The Handbook of Neurotoxicity is thus an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience, and is an indispensable tool for laboratory investigators, neuroscientists, and clinical researchers.

Medicine. --- Neurosciences. --- Biomedicine. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system

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This handbook is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments – to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners including those 1) afforded by therapeutic agents – clinical and preclinical; or 2) by non-drug means, such as exercise. The amorphous term ‘neurotoxin’ is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction – akin to a neurotoxin’s effect. This new edition significantly expands on the information provided in the first edition, providing the latest research in neurotoxicity and highlighting the relationship between specific neurotoxins and the neurodegenerative disorders they can cause. It also includes new sections on the neurotoxicity of heavy metals, fungi, and snake venom. The Handbook of Neurotoxicity is thus an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience, and is an indispensable tool for laboratory investigators, neuroscientists, and clinical researchers.

General biochemistry --- Physiology of nerves and sense organs --- Toxicology --- neurochemie --- multimedia --- Neurophysiology. --- Neurons. --- Nervous system --- Toxicology. --- Neurochemistry. --- Cellular Neuroscience. --- Neurological Disorders. --- Diseases. --- Neurotoxicologia

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This book is authored by leading experts who made major discoveries in neuroteratology research focused on modeling human neural developmental disorders. Individual chapters address ADHD (attention-deficit hyperactivity disorder), Lesch-Nyhan disease, psychoses and schizophrenia, autism, and models of Parkinson’s Disease and tardive dyskinesia. The effects of perinatal stress and agonist insults on life-long outcomes are addressed, as well as the overall effects of perinatal neurotoxins on development of specific neural phenotypic systems. The book provides a unique compendium on how perinatal insults of various types can produce effects in brain that persist throughout the life span. Researchers can derive insight into experimental approaches in this research field; clinicians can develop insights into the influences of the many noxious and seemingly innocuous substances that might influence brain development in children.

Medicine. --- Neurosciences. --- Psychopharmacology. --- Neurobiology. --- Biomedicine. --- Nervous system --- Diseases. --- Medical neurology --- Nerves --- Neuropathology --- Diseases --- Neurologic disorders --- Neurological disorders --- Neurology --- Neurosciences --- Behavioral pharmacology --- Drugs --- Chemotherapy --- Pharmacology --- Psychotropic drugs --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Psychotropic effects

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Brain disorders (neurodevelopmental, neurodegenerative, and affective disorders) can be investigated, treated, and prevented using person-centered methods. Because researchers have not reached a clear consensus on whether or not personality is stable or changeable, it has been difficult to outline how to use these methods in the care of people with brain disorders. Thus, the first part aims to identify the ways in which brain disorders and personality are linked. The second part explores different person-centered approaches that can be incorporated in a healthcare or education setting to help people with various brain disorders and to promote physical, mental and social health. The third part focuses on challenges and new venues.

Personality disorders. --- Brain --- Diseases. --- Brain diseases --- Psychology, Pathological --- Disorders of personality --- Personality --- Personality, Disorders of --- Disorders --- Neurosciences. --- Psychology, clinical. --- Neuropsychology. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Neurophysiology --- Psychophysiology

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