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This book is an open access under a CC BY license. The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but “naturally irreversible” complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book.

Medicine. --- Proteins. --- Biology --- Biomedicine. --- Biomedicine general. --- Protein Science. --- Protein-Ligand Interactions. --- Biological Techniques. --- Technique. --- Proteids --- Clinical sciences --- Medical profession --- Biomolecules --- Polypeptides --- Proteomics --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Biochemistry. --- RNA-ligand interactions. --- Cytology --- Research --- Methodology. --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Composition --- Health Workforce --- Biomedicine, general. --- Proteins . --- Biology—Technique.

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This open-access textbook is an excellent introduction to systems biology, which has developed rapidly in recent years. It discusses the processes in living organisms in an integrated way, enabling the reader to understand the fundamental principles and cause-effect relationships in biology and biochemistry. The authors have chosen an original but at the same time clear way of presenting the topics, repeatedly drawing comparisons and models from the macroscopic world and making the reader aware of the unity of the laws of physics, chemistry and biology. The fully updated 2nd edition also contains information that has only become available as a result of the increase in knowledge in recent years. This includes information on tumorigenesis, where significant progress has been made due to the explosive development of genetic knowledge as well as bioengineering with a highly effective technique adopted from the solutions of the bacterial world, such as CRISPR/CAS. This richly illustrated book is essential for postgraduate students and scientists of the following disciplines: biology, biotechnology, medicine, bioinformatics, robotics and automation, biocybernetics, and biomedical engineering. It is also an exciting read for anyone interested in biology.

Bioinformatics. --- Cytology. --- Medicine --- Biology --- Computational and Systems Biology. --- Cell Biology. --- Biomedical Research. --- Research. --- Health Workforce --- Biological research --- Biomedical research --- Cell biology --- Cellular biology --- Cells --- Bio-informatics --- Biological informatics --- Information science --- Computational biology --- Systems biology --- Data processing

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