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Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result in death.Over the last decade, the field of neurotrauma has witnessed significant advances, especially at the molecular, cellular, and behavioral levels. This progress is largely due to the introduction of novel techniques, as well as the development of new animal models of central nervous system (CNS) injury. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects provides a comprehensive

Brain damage --- Brain --- Patients --- Rehabilitation. --- Wounds and injuries --- Complications. --- Diagnosis.

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This second edition volume expands on the previous edition with updates to chapters and new chapters discussing the latest research in neuropsychiatric diseases. The chapters in this book are organized into eleven sections and cover the diversity and utility of animal models of psychiatric disorders, their development, modeling, and pathophysiological and molecular profiles. Part One looks at experimental modeling of neuropsychiatric studies and the usefulness and need of animal models. Parts Two and Three focus on experimental models of neuropsychiatric illnesses, including self-injurious behavior, bipolar disorder, anxiety, and learning and decision-making testing. Parts Four and Five discuss animal models of substance abuse. Part Six describes protocols to examine animal models related to maladaptive eating habits and behaviors. Parts Seven and Eight cover neurodegenerative diseases stemming from natural causes (aging), abnormal genetic backgrounds, or those brought on by trauma. Part Nine talks about inflammatory and metabolic alteration profiles relevant to autism spectrum disorders and depression. Parts Ten and Eleven conclude the book with a discussion on genetics, epigenetics, and system biology in the field of psychiatric disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Psychiatric Disorders: Methods and Protocols, Second Edition is a useful resource for graduates, postdoctoral workers, and established scientists working in the fields of behavioral and molecular neuropsychiatric research. .

Neurosciences. --- Psychiatry. --- Medicine and psychology --- Mental health --- Psychology, Pathological --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Psicopatologia --- Neuropsiquiatria --- Investigació mèdica --- Manuals de laboratori --- Tècniques de laboratori --- Investigació biomèdica --- Investigació --- Investigació farmacèutica --- Experimentació humana en medicina --- Ressenyes sistemàtiques (Investigació mèdica) --- Animals de laboratori --- Neurologia conductual --- Neurologia de la conducta --- Cervell --- Neuropsiquiatria geriàtrica --- Neuropsiquiatria pediàtrica --- Psiquiatria --- Aberracions mentals --- Patologia mental --- Psicologia patològica --- Trastorns mentals --- Neurologia --- Salut mental --- Abús de substàncies --- Afàsia --- Complex d'Èdip --- Complexos (Psicologia) --- Conducta compulsiva --- Conducta estereotipada (Psiquiatria) --- Deficiència mental --- Depressió psíquica --- Estupidesa --- Estupor (Patologia) --- Fatiga mental --- Grafomania --- Hipocòndria --- Histèria --- Lesions cerebrals --- Malalties mentals --- Medicina psicosomàtica --- Narcisisme --- Neurosi --- Paranoia --- Psicologia forense --- Psicopatologia de l'adolescència --- Psicopatologia infantil --- Psicosi --- Trastorns afectius --- Trastorns de la cognició --- Trastorns de la conducta --- Trastorns de la conducta alimentària --- Trastorns de la gana --- Trastorns de la percepció --- Trastorns de la personalitat --- Trastorns de pànic --- Trastorns psiquiàtrics postpart --- Traumes psíquics --- Malalties cerebrals --- Psicoanàlisi --- Psicologia criminal --- Psicologia mèdica

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Mental health. --- Nutrition --- Psychological aspects. --- Appetite --- Food preferences --- Emotional health --- Mental hygiene --- Mental physiology and hygiene --- Happiness --- Health --- Public health --- Mental illness --- Psychiatry --- Psychology --- Psychology, Pathological --- Salut mental --- Nutrició --- Aspectes psicològics

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This new edition provides updated and novel protocols of neuroproteomics methods that encompass both global-scale as well as targeted and specialized topics, which are timely additions for the molecular and phenotypic analysis of the central nervous system and CNS-related disorders. The detailed contents of this book include the exploration of several exciting areas of advanced methods used for neuroproteomics research including relative and absolute protein quantitation by mass spectrometry, characterization of post-translational modifications, as well as bioinformatics and computational approaches. Written for the highly successful Methods in Molecular Biology series, methodology chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Updated and accessible, Neuroproteomics: Methods and Protocols, Second Edition serves researchers and clinical scientists involved in the area of biomarker research and protein biochemistry, as well as molecular biologists and biochemists who have been involved in proteomics research already or even for those new to the field.

Neurosciences. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system

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