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This book focuses on data describing the roles of free radicals and related reactive species, and antioxidants, in the causes and treatments of diseases, examining both clinical and pre-clinical trials, as well as basic research. The book is divided into sub-sections with chapters on toxicological mechanisms, agents that produce toxicity, and special topics including areas such as antioxidant supplements, oxygen toxicity, toxicogenomics, and marine biology. Studies on Experimental Toxicology and Pharmacology promotes the concept of using biomarkers of free radical- and reactive species-induced injury as adjuncts to classical laboratory testing and the ability of antioxidants to provide cellular protection. There is increasing evidence that free radicals and other reactive species are causative, or at least supporting factors, that impact organisms and cause numerous tissue disorders. With contributions from international experts in the field, this volume is a valuable resource for researchers and postgraduate students in toxicology and related fields, as well as clinicians and clinical researchers.

Cytology --- Biology --- Health & Biological Sciences --- Toxicology. --- Pharmacology. --- Drug effects --- Medical pharmacology --- Chemicals --- Toxicology --- Life sciences. --- Apoptosis. --- Oxidative stress. --- Environmental health. --- Life Sciences. --- Oxidative Stress. --- Pharmacology/Toxicology. --- Environmental Health. --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Physiological effect --- Cytology. --- Environmental Medicine. --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Toxicological Phenomena. --- Pharmacological Phenomena. --- Pharmacologic Phenomena --- Pharmacologic Phenomenon --- Pharmacologic Process --- Pharmacological Concepts --- Pharmacological Phenomenon --- Pharmacologic Processes --- Pharmacological Processes --- Concept, Pharmacological --- Concepts, Pharmacological --- Pharmacological Concept --- Phenomena, Pharmacologic --- Phenomena, Pharmacological --- Phenomenon, Pharmacologic --- Phenomenon, Pharmacological --- Process, Pharmacologic --- Processes, Pharmacologic --- Processes, Pharmacological --- Stress, Oxidative --- Oxidative Stresses --- Stresses, Oxidative --- Nitrosative Stress --- Antioxidants --- Reactive Oxygen Species --- Toxicologic Phenomena --- Toxicologic Phenomenon --- Toxicological Concepts --- Toxicological Phenomenon --- Concept, Toxicological --- Concepts, Toxicological --- Phenomena, Toxicologic --- Phenomena, Toxicological --- Phenomenon, Toxicologic --- Phenomenon, Toxicological --- Toxicological Concept --- Environmental quality --- Health --- Health ecology --- Public health --- Environmental engineering --- Health risk assessment --- Cell death --- Oxidation-reduction reaction --- Stress (Physiology) --- Health aspects --- Environmental aspects --- Anti-oxidative Stress --- Antioxidative Stress --- DNA Oxidative Damage --- Nitro-Oxidative Stress --- Oxidative Cleavage --- Oxidative DNA Damage --- Oxidative Damage --- Oxidative Injury --- Oxidative Nitrative Stress --- Oxidative Stress Injury --- Oxidative and Nitrosative Stress --- Anti oxidative Stress --- Anti-oxidative Stresses --- Antioxidative Stresses --- Cleavage, Oxidative --- DNA Damage, Oxidative --- DNA Oxidative Damages --- Damage, DNA Oxidative --- Damage, Oxidative --- Damage, Oxidative DNA --- Injury, Oxidative --- Injury, Oxidative Stress --- Nitrative Stress, Oxidative --- Nitro Oxidative Stress --- Nitro-Oxidative Stresses --- Oxidative Cleavages --- Oxidative DNA Damages --- Oxidative Damage, DNA --- Oxidative Damages --- Oxidative Injuries --- Oxidative Nitrative Stresses --- Oxidative Stress Injuries --- Stress Injury, Oxidative --- Stress, Anti-oxidative --- Stress, Antioxidative --- Stress, Nitro-Oxidative --- Stress, Oxidative Nitrative --- Stresses, Nitro-Oxidative