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This book gives an updated review of the state of the art in regenerative cell therapy in the fields of cardiology, hematology, pediatrics, neurology, orthopedics and infectious diseases. The book emphasizes clinical advances as proof of concept in cell therapy based on the revolutionizing observation that regeneration can occur throughout the body even in highly differentiated organs like the heart and the neuronal system. It provides examples of breakthroughs in the clinical implementation of adult stem cell therapy.

Cellular therapy. --- Regeneration (Biology). --- Stem cells -- Transplantation. --- Cellular therapy --- Regeneration (Biology) --- Stem cells --- Immunotherapy, Adoptive --- Tissue Engineering --- Regeneration --- Hematopoietic Stem Cell Transplantation --- Stem Cell Transplantation --- Regenerative Medicine --- Adoptive Transfer --- Cell Transplantation --- Medicine --- Biological Processes --- Culture Techniques --- Immunization, Passive --- Biological Phenomena --- Health Occupations --- Transplantation --- Clinical Laboratory Techniques --- Immunization --- Investigative Techniques --- Disciplines and Occupations --- Phenomena and Processes --- Surgical Procedures, Operative --- Immunotherapy --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Immunologic Techniques --- Immunomodulation --- Biological Therapy --- Therapeutics --- Pharmacy, Therapeutics, & Pharmacology --- Oncology --- Health & Biological Sciences --- Transplantation. --- Stem cell transplantation --- Regenerative biology --- Regrowth (Biology) --- Medicine. --- Hematology. --- Oncology. --- Orthopedics. --- Pediatrics. --- Medicine & Public Health. --- Developmental biology --- Autotomy --- Wound healing --- Cell therapy --- Cells --- Therapy, Cellular --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Therapeutic use --- Oncology  . --- Paediatrics --- Pediatric medicine --- Children --- Orthopaedics --- Orthopedia --- Surgery --- Haematology --- Internal medicine --- Blood --- Tumors --- Diseases --- Health and hygiene --- Tissue therapy

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Mesenchymal Stromal Cell (MSC) biology has been studied for more than 4 decades and the cells have been investigated for potential clinical applications for more than 15 years. Progress has become exponential over the past decade due mainly to the broad therapeutic potential of these cells.   However, MSC studies have also been subject to controversy and increasing scrutiny as new mechanisms of action are reported and ever-expanding therapeutic applications pursued. In this book, leading authorities from all over the world, who are actively involved in this field, provide state-of-the-art knowledge of the basic biology, translational requirements and latest clinical experience with MSCs.  This cutting edge book is the ideal resource for scientists and clinicians interested in pursuing an important and rapidly developing field of research that will eventually help patients and address urgent unmet medical needs. Features include: Coverage of the biology of MSCs, latest understanding of  mechanisms of action, and role in tissue homeostasis and regeneration Identifying the potential of MSCs in proceeding from bench to bedside from regulatory , GMP production, ethical and safety aspects Critical analysis of clinical studies and the potential of MSCs to treat a wide variety of human diseases and tissues.   .

Histology. Cytology --- Biology --- Biotechnology --- klinische chemie --- stamcellen --- biologie --- biotechnologie --- cytologie --- stamceltransplantatie --- histologie