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This book is an in-depth and user-friendly reference for better understanding immune-mediated skin diseases and their therapies. The focus is on the needs of the physician, resident, or student to understand the pathophysiology of the disease as well as the mechanisms of action of the therapies. Clinical and Basic Immunodermatology, Second Edition is an effective teaching tool that has practical applications for use on a daily basis. It is a valuable resource for practicing dermatologists, dermatology residents and students, and healthcare workers in related fields.

Medicine. --- Immunology. --- Allergy. --- Dermatology. --- Infectious diseases. --- Medicine & Public Health. --- Infectious Diseases. --- Allergology. --- Allergic diseases --- Allergies --- Hypersensitivity --- Hypersensitivity, Immediate --- Immediate allergy --- Immediate hypersensitivity --- Immunobiology --- Clinical sciences --- Medical profession --- Communicable diseases --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Emerging infectious diseases. --- Medicine --- Skin --- Immunologic diseases --- Immunoglobulin E --- Life sciences --- Serology --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Diseases --- Immunological aspects. --- Immunodermatology

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This review emphasizes the pathologic features of psoriatic lesions, recent genetic studies of psoriasis, and immunologic factors in the disease. The evolution of a psoriatic lesion entails a complex interplay between environmental and genetic factors, which sets the scene for a cascade of events that activate dendritic cells and T cells. Cross-talk between epithelial cells and immune cells shapes and maintains the inflammatory milieu.

Skin --- Medicine --- Surgery