Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The subject of optogenetics is comprehensively covered in this book, including physical, chemical, and biological topics of light-sensing proteins and their application in biological systems, particularly in neuroscience and medicine and the related opto-electronics. Optogenetics is a new technology that combines genetics and optics. It enables one to manipulate or measure the function of identified cells or neurons in a tissue by light with an accuracy in the range of milliseconds, even in a freely moving animal. Optogenetics has already become a powerful tool for revealing the neural mechanisms underlying behavior and analyzing various physiological phenomena. It is also expected to become useful for treating neural dysfunctions such as Parkinson disease and for the development of a brain–machine interface. This book should be read by any scientist or student performing research in any way related to optogenetics. As a milestone publication on optogenetics, this book will serve as a compass for any researcher, from beginners to experts, to explore this uncharted world.

Biomedicine. --- Neurosciences. --- Cell Biology. --- Protein Science. --- Medicine. --- Biochemistry. --- Cytology. --- Médecine --- Neurosciences --- Biochimie --- Cytologie --- Medicine --- Health & Biological Sciences --- Neurology --- Optogenetics. --- Proteins. --- Cell biology. --- Genetic engineering --- Optical engineering --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Neural sciences --- Neurological sciences --- Neuroscience --- Nervous system --- Composition --- Proteins . --- Proteids --- Biomolecules --- Polypeptides --- Proteomics

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book presents the most advanced review available of all aspects of π-electron systems, including novel structures, new synthetic protocols, chemical and physical properties, spectroscopic and computational insights, molecular engineering, device properties, and physiological properties. π-Electron systems are ubiquitous in nature. Plants convert light energy into chemical energy by photosynthetic processes, in which chlorophylls and other porphyrinoids play an important role. On the one hand, research to learn about photosynthesis from nature has led to understanding of electron and energy transfer processes and to achieving artificial energy conversion systems inspired by nature. On the other hand, recent advances in organic and inorganic chemistry make it possible to construct novel π-electron systems that had never existed in nature. The authors of this book are from a variety of research fields including organic chemistry, inorganic chemistry, physical chemistry, materials science, and biology, providing a comprehensive overview of π-electron systems for a broad readership. Not only specialists but also graduate students working in π-electron systems will find the book of great interest. Throughout, the diverse potential for future fruitful applications of π-electron systems is revealed to the reader.

Biochemistry --- Chemistry --- Physical Sciences & Mathematics --- Electrons. --- Corpuscular theory of matter --- Chemistry. --- Organic chemistry. --- Physical chemistry. --- Nanochemistry. --- Biochemistry. --- Nanotechnology. --- Organic Chemistry. --- Nanotechnology and Microengineering. --- Physical Chemistry. --- Biochemistry, general. --- Molecular technology --- Nanoscale technology --- High technology --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Nanoscale chemistry --- Chemistry, Analytic --- Nanoscience --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Organic chemistry --- Physical sciences --- Composition --- Atoms --- Leptons (Nuclear physics) --- Matter --- Particles (Nuclear physics) --- Cathode rays --- Ions --- Positrons --- Constitution --- Chemistry, Organic. --- Engineering. --- Chemistry, Physical organic. --- Chemistry, Physical organic --- Chemistry, Organic --- Chemistry, Physical and theoretical --- Construction --- Industrial arts --- Technology --- Analytical chemistry

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book, now in a thoroughly revised second edition, offers a comprehensive review of the rapidly growing field of optogenetics, in which light-sensing proteins are genetically engineered into cells in order to acquire information on cellular physiology in optical form or to enable control of specific network in the brain upon activation by light. Light-sensing proteins of various living organisms are now available to be exogenously expressed in neurons and other target cells both in vivo and in vitro. Cellular functions can thus be manipulated or probed by light. The new edition documents fully the extensive progress since publication of the first edition to provide an up-to-date overview of the physical, chemical, and biological properties of light-sensing proteins and their application in biological systems, particularly in neuroscience but also in medicine and the optical sciences. Underlying principles are explained and detailed information provided on a wide range of optogenetic tools for the observation and control of cellular signaling and physiology, gene targeting technologies, and optical methods for biological applications. In presenting the current status of optogenetics and emerging directions, this milestone publication will be a "must read" for all involved in research in any way related to optogenetics.

Psychology --- Histology. Cytology --- Neuropathology --- Biotechnology --- neurologie --- hersenen --- biotechnologie --- cytologie --- neuropsychologie --- histologie