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This book discusses approaches based on multifunctional and targeted theranostic nanomedicines for improving diagnosis and drug delivery. It explores nanomedicines based on nanocarriers like liposomes, ethosomes, niosomes, polymeric nanoparticles, lipidic nanoparticles, metallic nanoparticles, micelles, dendrimers, quantum dots, carbon-based nanomaterials including carbon nanotubes, carbon dots, carbon quantum dots, graphene oxide, and fullerene. This book reviews designing, conjugation, optimization, formulation and development, and scale-up of multifunctional and targeted theranostic nanomedicines. It examines major challenges in developing nanomaterials that can be applied to nanomedicine with high biocompatibility and biodegradability for diagnostic and therapeutic purposes. Lastly, it addresses the most promising approaches at both commercialization and regulatory steps for bringing theranostic nanomedicine from research laboratories to clinics for patient use.

Nanomedicine. --- Medicine --- Nanotechnology --- Pharmaceutical chemistry. --- Therapeutics. --- Drug delivery systems. --- Pharmaceutics. --- Nanomedicine and Nanotoxicology. --- Drug Delivery. --- Delivery systems, Drug --- Drug administration technology --- Drug delivery technology --- Drugs --- Pharmaceutical technology --- Medical treatment --- Therapy --- Treatment of diseases --- Treatments for diseases --- Clinical medicine --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Delivery systems

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Pharmacology. Therapy --- farmacologie

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Knowledge Engineering (KE) is a fi eld within artifi cial intelligence that develops knowledgebased systems. KE is the process of imitating how a human expert in a specifi c domain would act and take decisions. It contains large amounts of knowledge, like metadata and information about a data object that describes characteristics such as content, quality, and format, structure and processes. Such systems are computer programs that are the basis of how a decision is made or a conclusion is reached. It is having all the rules and reasoning mechanisms to provide solutions to real-world problems. This book presents an extensive collection of the recent fi ndings and innovative research in the information system and KE domain. Highlighting the challenges and diffi culties in implementing these approaches, this book is a critical reference source for academicians, professionals, engineers, technology designers, analysts, undergraduate and postgraduate students in computing science and related disciplines such as Information systems, Knowledge Engineering, Intelligent Systems, Artifi cial Intelligence, Cognitive Neuro - science, and Robotics. In addition, anyone who is interested or involved in sophisticated information systems and knowledge engineering developments will fi nd this book a valuable source of ideas and guidance.

Information resources management. --- Information resources management --- Corporations --- Information resource management --- Information systems management --- IRM (Information resources management) --- Management --- Management information systems --- Security measures.