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Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer  and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs. The last decades were characterized by substantial progress in the understanding of the role of the immune system in tumor progression. Researchers have learned how to manipulate the immune system to generate tumor specific immune response, which raises high expectations for immunotherapy  to provide breakthroughs in cancer treatment.  It is increasingly clear that tumor-induced abnormalities in the immune system not only hampers natural tumor immune surveillance,  but also limits the effect of cancer immunotherapy. Therefore, it is critically important to understand the mechanisms of tumor-induced immune  suppression to make any progress in the field and this monograph provides these important insights.

Cytology. --- Developmental biology. --- Human genetics. --- Immunology. --- Immunosuppression. --- Immunotherapy -- Methods. --- Medicine. --- Microbiology. --- Tumors --- Immunosuppression --- Diseases --- Lymphocytes --- Immunomodulation --- CD4-Positive T-Lymphocytes --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biological Therapy --- Leukocytes, Mononuclear --- Leukocytes --- Therapeutics --- Blood Cells --- Immune System --- Blood --- Hemic and Immune Systems --- Cells --- Anatomy --- T-Lymphocytes, Regulatory --- T-Lymphocytes --- Neoplasms --- Methods --- Immunotherapy --- Medicine --- Biology --- Health & Biological Sciences --- Oncology --- Microbiology & Immunology --- Immunological aspects --- Immunological aspects. --- Depression, Immune --- Immune depression --- Immune suppression --- Immunodepression --- Suppression, Immune --- Tumor immunology --- Cancer research. --- Medical microbiology. --- Cell biology. --- Biomedicine. --- Cancer Research. --- Medical Microbiology. --- Cell Biology. --- Human Genetics. --- Developmental Biology. --- Immune response --- Immunological tolerance --- Immunodeficiency --- Regulation --- Oncology. --- Development (Biology) --- Growth --- Ontogeny --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Cell biology --- Cellular biology --- Cytologists --- Microbial biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Cancer research