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Outside cover back : "Every trainee in anaesthesia requires a thorough understanding of basic physiology and its application to clinical practice. Now in its second edition, this comprehensively illustrated textbook bridges the gap between medical school and reference scientific texts. It covers the physiology requirements of the Primary FRCA examination syllabus. Chapters are organised by organ system, with particular emphasis given to the respiratory, cardiovascular and nervous systems. The practical question-and-answer format helps the reader prepare for oral examinations, while 'clinical reference' boxes translate the physiological concepts to clinical practice. This new edition has been thoroughly updated and revised throughout, and includes six new chapters including the physiology of the eye, upper airway and exercise testing. It provides junior anaesthetists with an essential 'one stop' physiology resource."

Physiological Phenomena --- Anesthesiology --- methods --- Anesthesiology - methods

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Doctors and other health professionals are increasingly drawn towards research in the course of their training, often with little guidance on the skills, techniques and personal qualities required of a medical research worker. This short and helpful book has been written by three authors with long experience of performing and evaluating research in medicine. It provides essential advice for the beginner, covering in a practical and accessible fashion all the steps involved from choosing a research project to preparing and submitting a thesis. Now in its second edition, many important revisions have been made including updates on the use of computers, career implications, degree structures and ethical issues in human and animal experimentation. The illustrations by David Langdon provide a wry commentary on the ups and downs of life in research.

Dissertations, Academic. --- Education, Medical, Graduate. --- Medical writing. --- Medicine --- Research. --- Writing.

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Every trainee in anaesthesia requires a thorough understanding of basic physiology and its application to clinical practice. This comprehensively illustrated textbook bridges the gap between medical school and reference scientific texts. It covers the physiology requirements of the Primary FRCA examination syllabus. Chapters are organised by organ system, with particular emphasis given to the respiratory, cardiovascular and nervous systems. The practical question-and-answer format helps the reader prepare for the oral examination, while 'clinical relevance' boxes translate the physiological concepts to clinical practice. The authors include two medical physiologists and a Specialty Registrar in anaesthesia, and thereby bring a unique blend of expertise. This ensures that the book is up-to-date, accessible, and pitched appropriately for the trainee anaesthetist. Packed with easily understood, up-to-date and clinically relevant material, this convenient volume provides an essential 'one-stop' resource in physiology for junior anaesthetists.

Human physiology. --- Anesthetics --- Physiological effect.

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With upwards of 4.5 million deaths worldwide each year, and more than one tenth of these occurring in those with no previously documented heart disease, sudden arrhythmic death (SAD) is both a major public health burden and a highly emotive issue for society at large. Recent years have witnessed a marked expansion in our knowledge of the physiology underlying SAD, both in the context of hereditary and acquired cardiac disorders. Thanks largely to work in genetically modified animals, the growth in our understanding of mechanisms underlying arrhythmia in the hereditary channelopathies has been particularly marked. Our growing knowledge of the fundamental mechanisms underlying SAD has so far failed to spur substantial developments in clinical practice. Despite a large body of work in both humans and animals, it remains impossible to confidently identify those at high risk of SAD, making pre-emptive therapy a challenge. What is more, with the thankful exception of the implantable cardioverter-defibrillators and pharmacological agents in very specific situations, there has been depressingly little progress in finding new and effective therapies. This Research Topic aims to go some way towards bridging the gap between advances in basic science and the development and delivery of new therapies. It brings together original research contributions and review articles from key opinion leaders in the field, focusing on the direct clinical implications of the basic science research now and in the future.

Sudden death. --- Sudden death --- Cardiac arrest --- Prevention. --- Pathophysiology. --- Death --- Mortality --- Causes --- Arrest, Cardiac --- Cardiopulmonary arrest --- Heart arrest --- Sudden cardiac death --- Heart --- Heart failure --- Diseases --- ventricular arrhythmia --- Inherited arrhythmia syndromes --- sudden death --- arrhythmia mechanisms --- Channelopathies --- ventricular tachycardia --- cardiac modelling --- Ventricular Fibrillation --- Atrial Fibrillation --- Brugada Syndrome