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Drug development. --- Drug delivery systems. --- Delivery systems, Drug --- Drug administration technology --- Drug delivery technology --- Drugs --- Pharmaceutical technology --- Development of drugs --- New drug development --- Pharmacology --- Pharmacy --- Delivery systems --- Development

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Aerosols --- Aerosols --- Nebulizers and Vaporizers. --- Pulmonary Ventilation --- Aerosol therapy. --- Aérosolthérapie --- therapeutic use. --- pharmacology. --- physiology.

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With the goal of improving communication among diverse professionals involved in the manufacture of therapeutic agents-- from pharmaceutical researchers to chemical and industrial engineers, this volume summarizes the fundamental engineering principles and operations critical to converting bulk pharmaceutical products to patient-ready drug dosage delivery forms. The 15 chapters updating the out-of-print late 1960s text, Unit Processes in Pharmacy, cover such topics as heat and mass transfer, crystallization, size reduction and classification, sterilization, and bioprocessing. Hickey teaches at the School of Pharmacy at the U. of North Carolina at Chapel Hill, and is the president and CEO of a pharmaceutical company. Ganderton, with a Ph.D. from the U. of London, directs a pharmaceutical company in Bath. c. Book News Inc.

Biomedical Technology. --- Biomedical engineering. --- Chemical processes --- Chemical processes. --- Drugs. --- Mass production. --- Pharmaceutical Preparations. --- Pharmaceutical technology. --- Production engineering. --- Mathematical models.

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This distinctive text provides a toolbox for pharmaceutical scientists and those involved in product development utilizing pulmonary drug delivery systems. Uniquely focusing on aspects of control, both temporal and spatial, the text collects a broad range of interlinked chapters that provide both theoretical and practical insight.   Controlled Pulmonary Drug Delivery begins by examination of the foundations for pulmonary drug delivery: the macro and microstructure of the airways, lung clearance, airway absorption and transport, aerosol physics, and a historical overview of the field. Unlike other texts, these chapters are written specifically with drug delivery in mind. The science and technology of inhaler devices, technologies, materials, and particles systems are covered. Testing methods and techniques are discussed before regulatory perspectives and performance specifications conclude the text. The twenty two novel chapters in this volume each provide a theoretical and practical set of tools that comprise a comprehensive toolbox.   This volume will be of interest to scientists and engineers developing pulmonary drug delivery systems. The unique themes of controlled release science and technology that run through the book ensure that experienced and newcomers will greatly benefit from this book. As the importance for control over therapeutic performance is better recognized and demanded, this text will be essential for those delivering bioactives to the lung. Dr. Hugh Smyth is Assistant Professor of Pharmaceutics at the University of Texas, Austin. He is a recipient of the Young Investigator in Pharmaceutics and Pharmaceutical Technology Award of the American Association of Pharmaceutical Scientists and has edited a volume on pulmonary drug delivery. Drs. Hickey and Smyth share a research interest in the delivery of drugs to the lungs for the treatment and prevention of a number of diseases. Dr. Anthony Hickey is Professor of Molecular Pharmaceutics and Biomedical Engineering at the University of North Carolina at Chapel Hill. He is a fellow of the Institute of Biology, American Association of Pharmaceutical Scientists and the American Association for the Advancement of Science. He has published several edited and authored volumes in the fields of pharmaceutical aerosols, process engineering and particulate science.

Drug delivery systems. --- Drug targeting. --- Technology, Pharmaceutical. --- Aerosol therapy --- Drug delivery systems --- Drug Administration Routes --- Colloids --- Biological Science Disciplines --- Respiratory System --- Respiratory Tract Diseases --- Chemicals and Drugs --- Therapeutics --- Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Dosage Forms --- Anatomy --- Natural Science Disciplines --- Complex Mixtures --- Specialty Uses of Chemicals --- Disciplines and Occupations --- Chemical Actions and Uses --- Aerosols --- Lung --- Physiology --- Administration, Inhalation --- Drug Delivery Systems --- Lung Diseases --- Pharmaceutical Preparations --- Drug Therapy --- Medicine --- Health & Biological Sciences --- Respiratory System Diseases --- Pharmacy, Therapeutics, & Pharmacology --- Lungs --- Diseases. --- Delivery systems, Drug --- Drug administration technology --- Drug delivery technology --- Drugs --- Pulmonary diseases --- Delivery systems --- Medicine. --- Pharmaceutical technology. --- Biomedicine. --- Biomedicine general. --- Pharmaceutical Sciences/Technology. --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Pharmaceutical technology --- Health Workforce --- Biomedicine, general.

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Non-linear phenomena pervade the pharmaceutical sciences. Understanding the interface between each of these phenomena and the way in which they contribute to overarching processes such as pharmaceutical product development may ultimately result in more efficient, less costly and rapid implementation. The benefit to Society is self-evident in that affordable treatments would be rapidly forthcoming. We have aggregated these phenomena into one topic “Pharmaco-complexity: Non-linear Phenomena and Drug Product Development”.

Drug development. --- Drugs --- Chemotherapy. --- Design. --- Drug therapy --- Pharmacotherapy --- Therapeutics --- Pharmacology --- Development of drugs --- New drug development --- Pharmacy --- Drug design --- Pharmaceutical design --- Drug development --- Development --- Pharmaceutical technology. --- Pharmacotherapy. --- Pharmacy. --- Pharmaceutical Sciences/Technology. --- Chemistry --- Medicine --- Materia medica --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Farmacologia --- Medicina --- Biofarmàcia --- Biotransformació (Metabolisme) --- Dermofarmacologia --- Desenvolupament de medicaments --- Estabilitat dels medicaments --- Farmacocinètica --- Farmacogenètica --- Farmacologia cardiovascular --- Farmacologia clínica --- Farmacologia dental --- Farmacologia geriàtrica --- Farmacologia molecular --- Farmacologia obstètrica --- Farmacologia ocular --- Farmacologia pediàtrica --- Farmacologia respiratòria --- Farmacologia renal --- Farmacologia veterinària --- Immunofarmacologia --- Isòtops radioactius en farmacologia --- Neurofarmacologia --- Psicofarmacologia --- Química farmacèutica --- Radiofàrmacs --- Resistència als medicaments --- Toxicologia --- Medicaments --- Quimioteràpia --- Fotofarmacologia