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This text focuses on the American Cherokee people and the South Carolina settlers in the years 1680, when Charleston was established as the main town in the region, until 1785, when a treaty effectively removed the Cherokees from the region.

Cherokee Indians -- History. --- South Carolina -- History -- Colonial period, ca. 1600-1775. --- South Carolina -- History -- Revolution, 1775-1783. --- Cherokee Indians --- Gender & Ethnic Studies --- Ethnic & Race Studies --- Social Sciences --- History --- South Carolina --- Colonial period, ca. 1600-1775 --- Revolution, 1775-1783 --- History.