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The book comprehensively discusses the mechanisms of pathogenesis and drug resistance; current diagnostics landscape of four key human pathogens; bacterial, fungal, protozoans and viral which are the causes of major infectious diseases. It also assesses the emerging technologies for the detection and quantification of these pathogens. Further, it discusses the novel opportunities to fight against these infectious diseases and to identify pertinent drug targets with novel methodologies. It also reviews the current and future insights into the control, elimination, and eradication of these infectious diseases. Importantly, the book discusses the epidemiological characteristics and various challenges in combating Ebola and Influenza diseases. Finally, the book highlights the growing role of nanotechnology and bioinformatics resources for combating the infectious diseases. In summary, the book provides the mechanistic insight of the pathogenicity, drug-resistance, therapeutic strategies and identification of the novel drug targets of Mycobacterium tuberculosis, Plasmodium, Candida, Hepatitis C and emerging viral infections.
Parasitology. --- Infectious diseases. --- Drug resistance. --- Bioinformatics. --- Virology. --- Infectious Diseases. --- Drug Resistance. --- Microbiology --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Resistance to drugs --- Pharmacology --- Data processing --- Drug resistance in microorganisms. --- Communicable Diseases. --- Antimalarials. --- Antibiotic resistance in microorganisms --- Antibiotics resistance in microorganisms --- Bacterial resistance to antibiotics --- Drug resistance in micro-organisms --- Microbial drug resistance --- Resistance to drugs in microorganisms --- Microorganisms --- Anti-Malarials --- Antimalarial Agents --- Antimalarial Drugs --- Agents, Antimalarial --- Anti Malarials --- Drugs, Antimalarial --- Malaria --- Plasmodium --- Antirheumatic Agents --- Infectious Diseases --- Communicable Disease --- Disease, Communicable --- Disease, Infectious --- Diseases, Communicable --- Diseases, Infectious --- Infectious Disease --- Disease Outbreaks --- Disease Transmission, Infectious --- Resistance, Drug --- Pharmacogenetics --- Effect of drugs on --- Anti-Malarial --- Antimalarial --- Antimalarial Agent --- Antimalarial Drug --- Agent, Antimalarial --- Anti Malarial --- Drug, Antimalarial --- Resistència als medicaments --- Patologia --- Patologia humana --- Medicina --- Bacteriologia --- Càlculs --- Degeneració (Patologia) --- Diagnòstic de laboratori --- Estenosi --- Etiologia --- Genètica mèdica --- Glucòlisi --- Hipertròfia --- Histopatologia --- Hèrnia --- Immunopatologia --- Inflamació --- Insuficiència sistèmica --- Malformacions --- Metàstasi --- Paleopatologia --- Patologia cel·lular --- Patologia veterinària --- Teratologia --- Tumors --- Xoc --- Anatomia patològica --- Diagnòstic --- Farmacoresistència --- Farmacologia --- Resistència a la insulina --- Efecte dels medicaments sobre els microorganismes
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Parasitology. --- Communicable diseases --- Etiology. --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics --- Biology --- Malalties infeccioses --- Etiologia --- Biologia molecular --- Nanomedicina --- Medicina --- Nanotecnologia --- Biofísica molecular --- Bioquímica molecular --- Biofísica --- Bioquímica --- Histoquímica --- Biologia molecular vegetal --- Codi genètic --- Diagnòstic molecular --- Endocrinologia molecular --- Evolució molecular --- Farmacologia molecular --- Genètica molecular --- Glicòmica --- Metabolòmica --- Microbiologia molecular --- Neurobiologia molecular --- Patologia molecular --- Proteòmica --- Reconeixement molecular --- Biomolècules --- Causes de les malalties --- Diagnòstics etiològics --- Etiologia mèdica --- Patogènesi --- Patologia --- Accidents --- Infeccions --- Traumatisme --- Factors de risc en les malalties --- Contagi --- Malalties contagioses --- Malalties encomanadisses --- Malalties transmissibles --- Microbiologia mèdica --- Salut pública --- Abscessos --- Desinfecció --- Malalties bacterianes --- Malalties emergents --- Malalties infeccioses en els infants --- Malalties d'origen alimentari --- Malalties parasitàries --- Malalties per prions --- Malalties víriques --- Micosi --- Zoonosi
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Nanomedicine. --- Medicine --- Nanotechnology
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This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology.
General parasitology --- Medical microbiology, virology, parasitology --- medische microbiologie --- parasitologie --- virologie
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General parasitology --- Medical microbiology, virology, parasitology --- medische microbiologie --- parasitologie --- virologie
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This book aims to cover the applications of nanotechnology against human infectious diseases. The chapters of the book discuss the role of nanotechnology in the efficient diagnosis and treatment of these diseases. It explicitly provides an overview of nanodiagnostics for infectious diseases from nanoparticles-based, nanodevice-based, and point-of-care platforms. The book also covers the state-of-the-art review of recent progress in biomimetic and bioengineered nanotherapies to treat infectious diseases. It also presents a nano carrier-based CRISPR/Cas9 delivery system for gene editing and its applications for developing interventional approaches against communicable diseases. Further, it reviews the recent developments in nanotechnology to engineer nanoparticles with desired physicochemical properties as a line of defense against multi-drug resistance micro-organisms. Cutting across the disciplines, this book serves as a guide for researchers in biotechnology, parasitology, and nanotechnology.
General parasitology --- Histology. Cytology --- Medical microbiology, virology, parasitology --- parasitologie --- virologie --- bacteriologie
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The book explores Candida and candidiasis, and Aspergillus and aspergillosis, two significant fungal infectious diseases. In the first section, various aspects of Candida infection are covered. The book delves into the epidemiology of Candida infections, highlighting their prevalence and distribution. It thoroughly discusses diagnostics and pathogenesis of candidiasis, providing valuable insights into the identification, and understanding of the disease. Additionally, the book addresses the growing concern of drug resistance and provides an overview of current therapeutics for candidiasis. Chapters in the second section examine the epidemiology of Aspergillus infections, providing a comprehensive understanding of their occurrence and impact. It discusses the diagnostics and pathogenesis of aspergillosis, shedding light on the methods for accurate diagnosis and the mechanisms by which the infection develops. It explores the host-pathogen interaction and the role of biofilms in these infections. Furthermore, the book addresses the pressing issue of drug resistance in aspergillosis and presents an overview of therapeutic approaches available for managing the disease. This book serves as a valuable resource for researchers, clinicians, and healthcare professionals seeking in-depth knowledge of these fungal infectious diseases.
Microbiology. --- Fungi. --- Mycology. --- Biology. --- Oncogenic viruses. --- Drug delivery systems. --- Pharmacovigilance. --- Biological Sciences. --- Tumour Virus Infections. --- Drug Delivery. --- Drug Safety and Pharmacovigilance.
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